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Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway
scientific journal article
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instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
15452145
retrieved
31 January 2017
title
Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway
(English)
1 reference
stated in
PubMed
PubMed ID
15452145
retrieved
31 January 2017
main subject
Presenilin 1
1 reference
stated in
GOA release 2020-03-11
Intercellular adhesion molecule 5, telencephalin
1 reference
stated in
GOA release 2020-03-11
Golgi autoantigen, golgin subfamily a, 2
1 reference
stated in
GOA release 2020-03-11
Heat shock protein 5
1 reference
stated in
GOA release 2020-03-11
Cathepsin D
1 reference
stated in
GOA release 2020-03-11
Calnexin
1 reference
stated in
GOA release 2020-03-11
Lectin, mannose-binding, 1
1 reference
stated in
GOA release 2020-03-11
author
Viola Oorschot
series ordinal
2
object named as
Viola Oorschot
0 references
Judith Klumperman
series ordinal
10
object named as
Judith Klumperman
0 references
Bart De Strooper
series ordinal
9
object named as
Bart De Strooper
1 reference
stated in
PubMed
PubMed ID
15452145
retrieved
31 January 2017
Lutgarde Serneels
object named as
Lutgarde Serneels
series ordinal
6
1 reference
stated in
ORCID Public Data File 2021
author name string
Cary Esselens
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
15452145
retrieved
31 January 2017
Veerle Baert
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
15452145
retrieved
31 January 2017
Tim Raemaekers
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
15452145
retrieved
31 January 2017
Kurt Spittaels
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
15452145
retrieved
31 January 2017
Hui Zheng
series ordinal
7
1 reference
stated in
PubMed
PubMed ID
15452145
retrieved
31 January 2017
Paul Saftig
series ordinal
8
1 reference
stated in
PubMed
PubMed ID
15452145
retrieved
31 January 2017
Wim Annaert
series ordinal
11
1 reference
stated in
PubMed
PubMed ID
15452145
retrieved
31 January 2017
language of work or name
English
0 references
publication date
27 September 2004
1 reference
stated in
PubMed
PubMed ID
15452145
retrieved
31 January 2017
published in
Journal of Cell Biology
1 reference
stated in
PubMed
PubMed ID
15452145
retrieved
31 January 2017
volume
166
1 reference
stated in
PubMed
PubMed ID
15452145
retrieved
31 January 2017
page(s)
1041–1054
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stated in
PubMed
PubMed ID
15452145
retrieved
31 January 2017
issue
7
1 reference
stated in
PubMed
PubMed ID
15452145
retrieved
31 January 2017
cites work
Degradative organelles containing mislocalized alpha-and beta-synuclein proliferate in presenilin-1 null neurons
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PubMed Central
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Presenilin-1, Nicastrin, Amyloid Precursor Protein, and γ-Secretase Activity Are Co-localized in the Lysosomal Membrane
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PubMed Central
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17 March 2017
Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis
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PubMed Central
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17 March 2017
Interaction with telencephalin and the amyloid precursor protein predicts a ring structure for presenilins
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PubMed Central
reference URL
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17 March 2017
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Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein
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Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity
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Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration.
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29 September 2017
Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex
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PubMed Central
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29 September 2017
Autophagosome formation in mammalian cells
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29 September 2017
Arrayed adenoviral expression libraries for functional screening
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Alzheimer's disease-related overexpression of the cation-dependent mannose 6-phosphate receptor increases Abeta secretion: role for altered lysosomal hydrolase distribution in beta-amyloidogenesis
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29 September 2017
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Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells
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29 September 2017
Presenilin-1 exists in both pre- and post-Golgi compartments and recycles via COPI-coated membranes
1 reference
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PubMed Central
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3 June 2018
Presenilin-1 affects trafficking and processing of betaAPP and is targeted in a complex with nicastrin to the plasma membrane
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PubMed Central
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3 June 2018
Presenilin 1 controls gamma-secretase processing of amyloid precursor protein in pre-golgi compartments of hippocampal neurons
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3 June 2018
Presenilins mutated at Asp-257 or Asp-385 restore Pen-2 expression and Nicastrin glycosylation but remain catalytically inactive in the absence of wild type Presenilin
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27 November 2018
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Enhancement of hippocampal LTP, reference memory and sensorimotor gating in mutant mice lacking a telencephalon-specific cell adhesion molecule.
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27 November 2018
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27 November 2018
Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy.
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27 November 2018
Cathepsin D deficiency induces lysosomal storage with ceroid lipofuscin in mouse CNS neurons
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27 November 2018
Effects of PS1 deficiency on membrane protein trafficking in neurons.
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27 November 2018
Mutant human presenilin 1 protects presenilin 1 null mouse against embryonic lethality and elevates Abeta1-42/43 expression.
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27 November 2018
An ICAM-related neuronal glycoprotein, telencephalin, with brain segment-specific expression.
1 reference
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PubMed Central
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27 November 2018
Presenilin-mediated modulation of capacitative calcium entry
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15452145
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Presenilin-1 regulates intracellular trafficking and cell surface delivery of beta-amyloid precursor protein
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15452145
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1083/JCB.200406060
1 reference
stated in
PubMed
PubMed ID
15452145
retrieved
31 January 2017
PMCID
2172014
0 references
PubMed ID
15452145
1 reference
stated in
PubMed
PubMed ID
15452145
retrieved
31 January 2017
ResearchGate publication ID
8263518
0 references
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