(Q28592055)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112346%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

Mice lacking the ITIM-containing receptor G6b-B exhibit macrothrombocytopenia and aberrant platelet function (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112346%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

main subject

Giant platelet disorder

1 reference

Protein tyrosine phosphatase, non-receptor type 6

inferred from title

1 reference

Megakaryocyte and platelet inhibitory receptor G6b

1 reference

Protein tyrosine phosphatase, non-receptor type 11

1 reference

C-type lectin domain family 1, member b

1 reference

author

Alexandra Mazharian

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112346%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Paul Gissen

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112346%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Elizabeth Gardiner

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112346%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Steve P. Watson

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112346%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Yotis A Senis

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112346%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

author name string

Ying-Jie Wang

2

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112346%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Jun Mori

3

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112346%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Danai Bem

4

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112346%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Brenda Finney

5

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112346%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Silke Heising

6

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112346%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Bernhard Nieswandt

11

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112346%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

James G White

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112346%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Michael C Berndt

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112346%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Michael R Douglas

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112346%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Robert D Campbell

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112346%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

publication date

30 October 2012

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112346%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112346%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

volume

5

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112346%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

page(s)

ra78

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112346%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

issue

248

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112346%20AND%20SRC:MED&resulttype=core&format=json

Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases

16 February 2020

cites work

1 reference

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The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis

17 March 2017

1 reference

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PKCalpha regulates platelet granule secretion and thrombus formation in mice

17 March 2017

1 reference

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CEACAM1 negatively regulates platelet-collagen interactions and thrombus growth in vitro and in vivo

17 March 2017

1 reference

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Immunoreceptor tyrosine-based inhibition motifs: a quest in the past and future

17 March 2017

1 reference

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The novel inhibitory receptor G6B is expressed on the surface of platelets and attenuates platelet function in vitro

17 March 2017

1 reference

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Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins

17 March 2017

1 reference

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A critical role for the transcription factor Scl in platelet production during stress thrombopoiesis

17 March 2017

1 reference

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The molecular mechanisms that control thrombopoiesis

17 March 2017

1 reference

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GPVI and integrin alphaIIb beta3 signaling in platelets

17 March 2017

1 reference

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Src kinase regulation by phosphorylation and dephosphorylation

17 March 2017

1 reference

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Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse

17 March 2017

1 reference

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Platelet-collagen interaction: is GPVI the central receptor?

17 March 2017

1 reference

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Crystal structure of human protein-tyrosine phosphatase SHP-1

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

G6b, a novel immunoglobulin superfamily member encoded in the human major histocompatibility complex, interacts with SHP-1 and SHP-2

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

Expression and function of the mouse collagen receptor glycoprotein VI is strictly dependent on its association with the FcRgamma chain

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

Structural basis for substrate specificity of protein-tyrosine phosphatase SHP-1

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

Crystal structure of the tyrosine phosphatase SHP-2

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

Spatial constraints on the recognition of phosphoproteins by the tandem SH2 domains of the phosphatase SH-PTP2

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

G6b-B inhibits constitutive and agonist-induced signaling by glycoprotein VI and CLEC-2

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

Leukocyte-associated Ig-like receptor-1-deficient mice have an altered immune cell phenotype

7 April 2017

1 reference

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Dasatinib enhances megakaryocyte differentiation but inhibits platelet formation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

Leukocyte-associated immunoglobulin-like receptor-1 is expressed on human megakaryocytes and negatively regulates the maturation of primary megakaryocytic progenitors and cell line

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

Cytoskeletal mechanics of proplatelet maturation and platelet release.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

Novel clearance mechanisms of platelets

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

Co-expression of the collagen receptors leukocyte-associated immunoglobulin-like receptor-1 and glycoprotein VI on a subset of megakaryoblasts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

Critical role of Src-Syk-PLC{gamma}2 signaling in megakaryocyte migration and thrombopoiesis.

29 September 2017

1 reference

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Pathological interactions between hematopoietic stem cells and their niche revealed by mouse models of primary myelofibrosis

29 September 2017

1 reference

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Platelet-associated IgAs and impaired GPVI responses in platelets lacking WIP.

29 September 2017

1 reference

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Selective sorting of alpha-granule proteins

29 September 2017

1 reference

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TREM-like transcript-1 protects against inflammation-associated hemorrhage by facilitating platelet aggregation in mice and humans

29 September 2017

1 reference

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Platelet membrane proteomics: a novel repository for functional research

29 September 2017

1 reference

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The thrombocytopenia of WAS: a familial form of ITP?

29 September 2017

1 reference

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A nonsynonymous SNP in the ITGB3 gene disrupts the conserved membrane-proximal cytoplasmic salt bridge in the alphaIIbbeta3 integrin and cosegregates dominantly with abnormal proplatelet formation and macrothrombocytopenia

29 September 2017

1 reference

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Controlled shedding of platelet glycoprotein (GP)VI and GPIb-IX-V by ADAM family metalloproteinases.

29 September 2017

1 reference

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Minimal regulation of platelet activity by PECAM-1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

The C-type lectin receptors CLEC-2 and Dectin-1, but not DC-SIGN, signal via a novel YXXL-dependent signaling cascade

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

A novel role for PECAM-1 in megakaryocytokinesis and recovery of platelet counts in thrombocytopenic mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

A comprehensive proteomics and genomics analysis reveals novel transmembrane proteins in human platelets and mouse megakaryocytes including G6b-B, a novel immunoreceptor tyrosine-based inhibitory motif protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

Regulation of proplatelet formation and platelet release by integrin alpha IIb beta3.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

The platelet: form and function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

Rac1 is essential for platelet lamellipodia formation and aggregate stability under flow.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

Platelet PECAM-1 inhibits thrombus formation in vivo.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

Vav1 and vav3 have critical but redundant roles in mediating platelet activation by collagen.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

Megakaryocytes and beyond: the birth of platelets

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

A lineage-restricted and divergent beta-tubulin isoform is essential for the biogenesis, structure and function of blood platelets

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

Characterization of the hematopoietic transcription factor NF-E2 in primary murine megakaryocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

Differentially regulated GPVI ectodomain shedding by multiple platelet-expressed proteinases.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

Critical role for ERK1/2 in bone marrow and fetal liver-derived primary megakaryocyte differentiation, motility, and proplatelet formation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

Differential effects of reduced glycoprotein VI levels on activation of murine platelets by glycoprotein VI ligands

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

Revealing mechanisms for SH2 domain mediated regulation of the protein tyrosine phosphatase SHP-2.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4973664

Proteomic analysis of integrin alphaIIbbeta3 outside-in signaling reveals Src-kinase-independent phosphorylation of Dok-1 and Dok-3 leading to SHIP-1 interactions

3 June 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002936

Integrin alpha2beta1 mediates outside-in regulation of platelet spreading on collagen through activation of Src kinases and PLCgamma2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002936

The contribution of glycoprotein VI to stable platelet adhesion and thrombus formation illustrated by targeted gene deletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002936

Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates GPIbalpha shedding from platelets in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002936

Differentiation of murine committed megakaryocytic progenitors isolated by a novel strategy reveals the complexity of GATA and Ets factor involvement in megakaryocytopoiesis and an unexpected potential role for GATA-6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002936

Of mice and men: comparison of the ultrastructure of megakaryocytes and platelets

21 January 2018

1 reference

12 December 2020

CLEC-2 is an essential platelet-activating receptor in hemostasis and thrombosis

1 reference

12 December 2020

Potent stimulation of SH-PTP2 phosphatase activity by simultaneous occupancy of both SH2 domains

1 reference

12 December 2020

Visualization and manipulation of the platelet and megakaryocyte cytoskeleton

1 reference

12 December 2020

1 reference

12 December 2020

In vivo biotinylation demonstrates that reticulated platelets are the youngest platelets in circulation

1 reference

12 December 2020

ADP induces partial platelet aggregation without shape change and potentiates collagen-induced aggregation in the absence of Galphaq

1 reference

12 December 2020

Differential regulation of actin stress fiber assembly and proplatelet formation by alpha2beta1 integrin and GPVI in human megakaryocytes

1 reference

12 December 2020

10.1126/SCISIGNAL.2002936

Identifiers

DOI

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112346%20AND%20SRC:MED&resulttype=core&format=json

release_6mqdsuotfbagzczvkx2viht5ye

16 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/6mqdsuotfbagzczvkx2viht5ye

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112346%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112346%20AND%20SRC:MED&resulttype=core&format=json