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Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine
scientific journal article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
7903454
retrieved
3 February 2017
title
Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine
(English)
1 reference
stated in
PubMed
PubMed ID
7903454
retrieved
3 February 2017
author name string
I. Johansson
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
7903454
retrieved
3 February 2017
E. Lundqvist
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
7903454
retrieved
3 February 2017
L. Bertilsson
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
7903454
retrieved
3 February 2017
M. L. Dahl
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
7903454
retrieved
3 February 2017
F. Sjöqvist
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
7903454
retrieved
3 February 2017
M. Ingelman-Sundberg
series ordinal
6
1 reference
stated in
PubMed
PubMed ID
7903454
retrieved
3 February 2017
language of work or name
English
0 references
publication date
15 December 1993
1 reference
stated in
PubMed
PubMed ID
7903454
retrieved
3 February 2017
published in
Proceedings of the National Academy of Sciences of the United States of America
1 reference
stated in
PubMed
PubMed ID
7903454
retrieved
3 February 2017
volume
90
1 reference
stated in
PubMed
PubMed ID
7903454
retrieved
3 February 2017
page(s)
11825–11829
1 reference
stated in
PubMed
PubMed ID
7903454
retrieved
3 February 2017
issue
24
1 reference
stated in
PubMed
PubMed ID
7903454
retrieved
3 February 2017
cites work
Gene amplification
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=48077
retrieved
29 September 2017
Gene amplification in cultured animal cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=48077
retrieved
29 September 2017
Human debrisoquine 4-hydroxylase (P450IID1): cDNA and deduced amino acid sequence and assignment of the CYP2D locus to chromosome 22.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=48077
retrieved
29 September 2017
Human cancer and cellular oncogenes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=48077
retrieved
29 September 2017
DNA amplification in drug resistant cells and in tumours
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=48077
retrieved
29 September 2017
The molecular biology of cytochrome P450s.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=48077
retrieved
29 September 2017
De novo amplification within a "silent" human cholinesterase gene in a family subjected to prolonged exposure to organophosphorous insecticides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=48077
retrieved
29 September 2017
The human debrisoquine 4-hydroxylase (CYP2D) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=48077
retrieved
29 September 2017
DNA amplification is rare in normal human cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=48077
retrieved
29 September 2017
Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. Study of the functional significance of individual mutations by expression of chimeric genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=48077
retrieved
29 September 2017
Interethnic variation of drug metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=48077
retrieved
29 September 2017
Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolizers of the debrisoquine/sparteine polymorphism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=48077
retrieved
29 September 2017
Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquin and S-mephenytoin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=48077
retrieved
29 September 2017
Gene amplification causes overproduction of the first three enzymes of UMP synthesis in N-(phosphonacetyl)-L-aspartate-resistant hamster cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=48077
retrieved
29 September 2017
Extremely rapid hydroxylation of debrisoquine: a case report with implication for treatment with nortriptyline and other tricyclic antidepressants.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=48077
retrieved
3 June 2018
In vivo somatic mutations in human lymphocytes frequently result from major gene alterations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=48077
retrieved
3 June 2018
Evolution of a highly polymorphic human cytochrome P450 gene cluster: CYP2D6.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=48077
retrieved
3 June 2018
Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=48077
retrieved
3 June 2018
Molecular basis for rational megaprescribing in ultrarapid hydroxylators of debrisoquine
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/7903454
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
c-Ha-ras-1 proto-oncogene amplification and overexpression during the limited replicative life span of normal human fibroblasts
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/7903454
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/7903454
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Analysis of the CYP2D6 gene in relation to debrisoquin and desipramine hydroxylation in a Swedish population
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/7903454
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1073/PNAS.90.24.11825
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1539314
ADS bibcode
1993PNAS...9011825J
0 references
OpenCitations bibliographic resource ID
1539314
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1539314
PMCID
48077
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1539314
PubMed ID
7903454
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1539314
ResearchGate publication ID
15296686
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