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The protein kinase B/Akt signalling pathway in human malignancy
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scholarly article
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stated in
PubMed
PubMed ID
11882383
retrieved
3 February 2017
review article
1 reference
stated in
Europe PubMed Central
title
The protein kinase B/Akt signalling pathway in human malignancy
(English)
1 reference
stated in
PubMed
PubMed ID
11882383
retrieved
3 February 2017
author name string
Karleen M. Nicholson
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
11882383
retrieved
3 February 2017
Neil G. Anderson
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
11882383
retrieved
3 February 2017
publication date
1 May 2002
1 reference
stated in
PubMed
PubMed ID
11882383
retrieved
3 February 2017
published in
Cellular Signalling
1 reference
stated in
PubMed
PubMed ID
11882383
retrieved
3 February 2017
volume
14
1 reference
stated in
PubMed
PubMed ID
11882383
retrieved
3 February 2017
page(s)
381–395
1 reference
stated in
PubMed
PubMed ID
11882383
retrieved
3 February 2017
issue
5
1 reference
stated in
PubMed
PubMed ID
11882383
retrieved
3 February 2017
cites work
The Hallmarks of Cancer
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Crossref
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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
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7 January 2021
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Cellular survival: a play in three Akts
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https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
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7 January 2021
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Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
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7 January 2021
based on heuristic
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Molecular cloning and characterisation of a novel putative protein-serine kinase related to the cAMP-dependent and protein kinase C families
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
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7 January 2021
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Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Structural basis of 3-phosphoinositide recognition by pleckstrin homology domains
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reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular cloning of a second form of rac protein kinase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Developmental regulation of expression and activity of multiple forms of the Drosophila RAC protein kinase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of activation of protein kinase B by insulin and IGF-1
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular cloning and characterization of a new member of the RAC protein kinase family: association of the pleckstrin homology domain of three types of RAC protein kinase with protein kinase C subspecies and beta gamma subunits of G proteins
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two splice variants of protein kinase B gamma have different regulatory capacity depending on the presence or absence of the regulatory phosphorylation site serine 472 in the carboxyl-terminal hydrophobic domain
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dual regulation of platelet protein kinase B
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Integrin-linked kinase regulates phosphorylation of serine 473 of protein kinase B by an indirect mechanism.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of Akt/PKB activation by tyrosine phosphorylation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of Akt kinase activity by binding to Hsp90
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Domain swapping used to investigate the mechanism of protein kinase B regulation by 3-phosphoinositide-dependent protein kinase 1 and Ser473 kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Osmotic shock inhibits insulin signaling by maintaining Akt/protein kinase B in an inactive dephosphorylated state
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inactivation and dephosphorylation of protein kinase Balpha (PKBalpha) promoted by hyperosmotic stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
3-phosphoinositide-dependent protein kinase 1, an Akt1 kinase, is involved in dephosphorylation of Thr-308 of Akt1 in Chinese hamster ovary cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amplification of 19q13.1–q13.2 sequences in ovarian cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amplification and overexpression of the AKT2 oncogene in a subset of human pancreatic ductal adenocarcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PIK3CA is implicated as an oncogene in ovarian cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PIK3CA as an oncogene in cervical cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogenic kinase signalling
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular mechanisms underlying ErbB2/HER2 action in breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The ErbB signaling network: receptor heterodimerization in development and cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-kappaB pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PTEN: life as a tumor suppressor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanismsin haematological malignancies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The MMAC1 tumor suppressor phosphatase inhibits phospholipase C and integrin-linked kinase activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PTEN induces apoptosis and cell cycle arrest through phosphoinositol-3-kinase/Akt-dependent and -independent pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The inositol phosphatase SHIP inhibits Akt/PKB activation in B cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SHIP is a negative regulator of growth factor receptor-mediated PKB/Akt activation and myeloid cell survival
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
5' phospholipid phosphatase SHIP-2 causes protein kinase B inactivation and cell cycle arrest in glioblastoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peptide and protein library screening defines optimal substrate motifs for AKT/PKB.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of translocation in the activation and function of protein kinase B
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase B localization and activation differentially affect S6 kinase 1 activity and eukaryotic translation initiation factor 4E-binding protein 1 phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of phosphoinositide-dependent kinase 1 on protein kinase B translocation and its subsequent activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Translocation of Akt/PKB to the nucleus of osteoblast-like MC3T3-E1 cells exposed to proliferative growth factors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin-like growth factor-1-induced phosphorylation of the forkhead family transcription factor FKHRL1 is mediated by Akt kinase in PC12 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Forkhead homologue in rhabdomyosarcoma functions as a bifunctional nuclear receptor-interacting protein with both coactivator and corepressor functions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt/protein kinase B up-regulates Bcl-2 expression through cAMP-response element-binding protein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CREB is a regulatory target for the protein kinase Akt/PKB
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The antiapoptotic gene mcl-1 is up-regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through a transcription factor complex containing CREB
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NF-kappaB signals induce the expression of c-FLIP.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p21-activated kinase 1 phosphorylates the death agonist bad and protects cells from apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Akt proto-oncogene links Ras to Pak and cell survival signals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: involvement of MEK upstream of Bad phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dissociation of apoptosis from proliferation, protein kinase B activation, and BAD phosphorylation in interleukin-3-mediated phosphoinositide 3-kinase signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of bad phosphorylation and association with Bcl-x(L) by the MAPK/Erk kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p90(RSK) blocks bad-mediated cell death via a protein kinase C-dependent pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of BAD phosphorylation at serine 112 by the Ras-mitogen-activated protein kinase pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signal transduction by the JNK group of MAP kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of cell death protease caspase-9 by phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt regulates cell survival and apoptosis at a postmitochondrial level
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming activity and mitosis-related expression of the AKT2 oncogene: evidence suggesting a link between cell cycle regulation and oncogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Coordinate signaling by integrins and receptor tyrosine kinases in the regulation of G1 phase cell-cycle progression.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin D1 protein expression and function in human breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple ras effector pathways contribute to G(1) cell cycle progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin D1 expression mediated by phosphatidylinositol 3-kinase through mTOR-p70(S6K)-independent signaling in growth factor-stimulated NIH 3T3 fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin D Expression Is Controlled Post-transcriptionally via a Phosphatidylinositol 3-Kinase/Akt-dependent Pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glycogen Synthase Kinase-3 from Rabbit Skeletal Muscle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation. Characterization of dominant-negative mutant of PKB.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
GSK-3: new thoughts on an old enzyme
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
GSK3, a master switch regulating cell-fate specification and tumorigenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
beta-catenin is a target for the ubiquitin-proteasome pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt participation in the Wnt signaling pathway through Dishevelled
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of glycogen synthase kinase activity is not sufficient for leukemia enhancer factor-1 activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor suppressor PTEN inhibits nuclear accumulation of beta-catenin and T cell/lymphoid enhancer factor 1-mediated transcriptional activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TOR, a central controller of cell growth
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding protein-dependent pathways.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt-dependent phosphorylation of p21(Cip1) regulates PCNA binding and proliferation of endothelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased AKT activity contributes to prostate cancer progression by dramatically accelerating prostate tumor growth and diminishing p27Kip1 expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Angiopoietin-1 regulates endothelial cell survival through the phosphatidylinositol 3'-Kinase/Akt signal transduction pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of endothelium-derived nitric oxide production by the protein kinase Akt
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Akt kinase signals directly to endothelial nitric oxide synthase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt takes center stage in angiogenesis signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PTEN controls tumor-induced angiogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase B (PKB/Akt)--a key regulator of glucose transport?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role for Akt in mediating the estrogenic functions of epidermal growth factor and insulin-like growth factor I
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A survey of telomerase activity in human cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomerase is controlled by protein kinase Calpha in human breast cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of the hTERT telomerase catalytic subunit by the c-Abl tyrosine kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt protein kinase enhances human telomerase activity through phosphorylation of telomerase reverse transcriptase subunit
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Growth retardation and tumour inhibition by BRCA1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Location of BRCA1 in human breast and ovarian cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of BRCA1 with Rad51 in mitotic and meiotic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Heregulin induces phosphorylation of BRCA1 through phosphatidylinositol 3-Kinase/AKT in breast cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The akt kinase: molecular determinants of oncogenicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogenic transformation induced by membrane-targeted Akt2 and Akt3.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of Akt (protein kinase B) in mammary epithelium provides a critical cell survival signal required for tumor progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation and nuclear exclusion of the forkhead transcription factor FKHR after epidermal growth factor treatment in human breast cancer cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Forkhead transcription factors are targets of signalling by the proto-oncogene PKB (C-AKT).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt phosphorylates and regulates the orphan nuclear receptor Nur77
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation and regulation of Raf by Akt (protein kinase B)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900271-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0898-6568(01)00271-6
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2334391
OpenCitations bibliographic resource ID
2334391
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2334391
PubMed ID
11882383
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2334391
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