(Q28646376)

3 February 2017

title

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B (English)

1 reference

3 February 2017

Dual Role of Phosphatidylinositol-3,4,5-trisphosphate in the Activation of Protein Kinase B (English)

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.277.5325.567

8 November 2024

2

L. R. Stephens

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9228007

8 November 2024

Phillip Thomas Hawkins

9

object named as

P. T. Hawkins

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9228007

8 November 2024

author name string

D. Stokoe

1

1 reference

3 February 2017

T. Copeland

3

1 reference

3 February 2017

P. R. Gaffney

4

1 reference

3 February 2017

C. B. Reese

5

1 reference

3 February 2017

G. F. Painter

6

1 reference

3 February 2017

A. B. Holmes

7

1 reference

3 February 2017

F. McCormick

8

1 reference

3 February 2017

publication date

25 July 1997

1 reference

full work available at URL

3 February 2017

language of work or name

English

0 references

https://www.science.org/doi/pdf/10.1126/science.277.5325.567

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.277.5325.567

8 November 2024

1 reference

3 February 2017

volume

277

1 reference

3 February 2017

issue

5325

1 reference

3 February 2017

page(s)

567–570

1 reference

Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma

3 February 2017

cites work

1

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.277.5325.567

Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation

8 November 2024

4

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.277.5325.567

PH domains: diverse sequences with a common fold recruit signaling molecules to the cell surface

8 November 2024

5

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.277.5325.567

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

8 November 2024

6

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.277.5325.567

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

8 November 2024

7

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.277.5325.567

Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways

8 November 2024

9

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.277.5325.567

Constitutive activation of protein kinase B and phosphorylation of p47phox by a membrane-targeted phosphoinositide 3-kinase

8 November 2024

10

1 reference

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

8 November 2024

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1 reference

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PI3K: downstream AKTion blocks apoptosis

8 November 2024

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1 reference

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Mechanism of activation of protein kinase B by insulin and IGF-1

8 November 2024

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1 reference

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Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation

8 November 2024

14

1 reference

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A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain.

8 November 2024

15

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.277.5325.567

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

8 November 2024

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1 reference

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Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphosphate: a new intracellular signalling system?

8 November 2024

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1 reference

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Akt is a direct target of the phosphatidylinositol 3-kinase. Activation by growth factors, v-src and v-Ha-ras, in Sf9 and mammalian cells

8 November 2024

24

1 reference

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

8 November 2024

26

1 reference

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Complexes of polyoma virus medium T antigen and cellular proteins

8 November 2024

27

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.277.5325.567

The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101

8 November 2024

28

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.277.5325.567