(Q28705237)

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The long-term safety and efficacy of bilateral transplantation of human fetal striatal tissue in patients with mild to moderate Huntington's disease

scientific article (publication date: June 2013)

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22 February 2020

The long-term safety and efficacy of bilateral transplantation of human fetal striatal tissue in patients with mild to moderate Huntington's disease (English)

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22 February 2020

Huntington's disease

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Roger A. Barker

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22 February 2020

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22 February 2020

Barbara J. Sahakian

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22 February 2020

David J. Brooks

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22 February 2020

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22 February 2020

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22 February 2020

Stephen Dunnett

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22 February 2020

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Paola Piccini

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Sarah L Mason

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22 February 2020

Timothy P Harrower

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22 February 2020

Rachel A Swain

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22 February 2020

Raj Mathur

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22 February 2020

Sohier Elneil

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22 February 2020

Steven Thornton

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22 February 2020

Carrie Hurrelbrink

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22 February 2020

Richard J Armstrong

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22 February 2020

Pam Tyers

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22 February 2020

Emma Smith

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22 February 2020

Adrian Carpenter

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22 February 2020

Yen F Tai

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22 February 2020

Colin Watts

19

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22 February 2020

John D Pickard

20

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22 February 2020

NEST-UK collaboration

23

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22 February 2020

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23 January 2013

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22 February 2020

Journal of Neurology, Neurosurgery and Psychiatry

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22 February 2020

84

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22 February 2020

6

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22 February 2020

657-665

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22 February 2020

Core assessment program for intracerebral transplantations (CAPIT)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

17 March 2017

The Current Status of Neural Grafting in the Treatment of Huntington's Disease. A Review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

3 June 2018

Huntington's disease: from molecular pathogenesis to clinical treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

3 June 2018

Biological and clinical changes in premanifest and early stage Huntington's disease in the TRACK-HD study: the 12-month longitudinal analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

3 June 2018

Human striatal neuroblasts develop and build a striatal-like structure into the brain of Huntington's disease patients after transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

3 June 2018

Neural transplants in patients with Huntington's disease undergo disease-like neuronal degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

3 June 2018

A patient with Huntington's disease and long-surviving fetal neural transplants that developed mass lesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

3 June 2018

Neural transplantation in Huntington's disease: the NEST-UK donor tissue microbiological screening program and review of the literature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

3 June 2018

Effect of fetal neural transplants in patients with Huntington's disease 6 years after surgery: a long-term follow-up study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

3 June 2018

The paradigm of Huntington's disease: therapeutic opportunities in neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

3 June 2018

Profile of cognitive progression in early Huntington's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

3 June 2018

Staging and preparation of human fetal striatal tissue for neural transplantation in Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

3 June 2018

Unilateral transplantation of human primary fetal tissue in four patients with Huntington's disease: NEST-UK safety report ISRCTN no 36485475.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

3 June 2018

Clinical neurotransplantation: core assessment protocol rather than sham surgery as control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

3 June 2018

Loss of normal huntingtin function: new developments in Huntington's disease research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

3 June 2018

The integration and function of striatal grafts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

3 June 2018

Towards a protocol for the preparation and delivery of striatal tissue for clinical trials of transplantation in Huntington's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

3 June 2018

Differences in duration of Huntington's disease based on age at onset

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

3 June 2018

Executive and mnemonic functions in early Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

3 June 2018

What is needed versus what would be interesting to know before undertaking neural transplantation in patients with Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

3 June 2018

Survival and proliferation of nonneural tissues, with obstruction of cerebral ventricles, in a parkinsonian patient treated with fetal allografts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

3 June 2018

Rationale for intrastriatal grafting of striatal neuroblasts in patients with Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

3 June 2018

Technical factors that influence neural transplant safety in Huntington's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

27 November 2018

Hand tapping: a simple, reproducible, objective marker of motor dysfunction in Huntington's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

27 November 2018

Long-term clinical and positron emission tomography outcome of fetal striatal transplantation in Huntington's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

27 November 2018

Adjunctive use of the non-ionic surfactant Poloxamer 188 improves fetal dopaminergic cell survival and reinnervation in a neural transplantation strategy for Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

27 November 2018

Positron emission tomography after fetal transplantation in Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

27 November 2018

Evaluation of an MRI-based protocol for cell implantation in four patients with Huntington's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

27 November 2018

Striatal neural grafting improves cortical metabolism in Huntington's disease patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

27 November 2018

Progressive striatal and cortical dopamine receptor dysfunction in Huntington's disease: a PET study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

27 November 2018

Bilateral human fetal striatal transplantation in Huntington's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

27 November 2018

Motor and cognitive improvements in patients with Huntington's disease after neural transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

27 November 2018

Volume and differentiation of striatal grafts in rats: relationship to the number of cells implanted.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

27 November 2018

Unified Huntington's disease rating scale: Reliability and consistency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646287

27 November 2018

Assessment of striatal graft viability in the rat in vivo using a small diameter PET scanner

1 reference

https://pubmed.ncbi.nlm.nih.gov/23345280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Computerized assessment in neuropsychiatry using CANTAB: discussion paper

1 reference

https://pubmed.ncbi.nlm.nih.gov/23345280

12 December 2020

based on heuristic

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10.1136/JNNP-2012-302441

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22 February 2020

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22 February 2020

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22 February 2020

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