(Q28771733)

14 February 2017

title

NEDD8 ultimate buster-1 regulates the abundance of TRF1 at telomeres by promoting its proteasomal degradation (English)

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14 February 2017

Yu Young Jeong

1

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14 February 2017

Joonyoung Her

series ordinal

2

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14 February 2017

In Kwon Chung

series ordinal

3

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14 February 2017

language of work or name

English

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publication date

1 June 2016

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14 February 2017

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14 February 2017

volume

590

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14 February 2017

issue

12

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14 February 2017

page(s)

1776–1790

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Regulation of telomerase by telomeric proteins

14 February 2017

cites work

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Control of telomere length by the human telomeric protein TRF1

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Post-translational modifications of TRF1 and TRF2 and their roles in telomere maintenance.

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The role of the poly(ADP-ribose) polymerase tankyrase1 in telomere length control by the TRF1 component of the shelterin complex

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The F-box protein FBX4 targets PIN2/TRF1 for ubiquitin-mediated degradation and regulates telomere maintenance

21 January 2018

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Ubiquitin Ligase RLIM Modulates Telomere Length Homeostasis through a Proteolysis of TRF1.

21 January 2018

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Regulation of telomeric repeat binding factor 1 binding to telomeres by casein kinase 2-mediated phosphorylation

21 January 2018

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Plk1 phosphorylation of TRF1 is essential for its binding to telomeres

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The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins

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Ubiquitin-like proteins

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Targeting Neddylation pathways to inactivate cullin-RING ligases for anticancer therapy

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A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8

21 January 2018

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Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1

21 January 2018

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Protein neddylation: beyond cullin-RING ligases

21 January 2018

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Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation

21 January 2018

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Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity

21 January 2018

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Regulation of parkin and PINK1 by neddylation

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The covalent modifier Nedd8 is critical for the activation of Smurf1 ubiquitin ligase in tumorigenesis

21 January 2018

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NEDDylation regulates E2F-1-dependent transcription

21 January 2018

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Conjugation to Nedd8 instigates ubiquitylation and down-regulation of activated receptor tyrosine kinases

21 January 2018

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pVHL modification by NEDD8 is required for fibronectin matrix assembly and suppression of tumor development

21 January 2018

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The ubiquitin E1 enzyme Ube1 mediates NEDD8 activation under diverse stress conditions

21 January 2018

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Changes in the ratio of free NEDD8 to ubiquitin triggers NEDDylation by ubiquitin enzymes

21 January 2018

1 reference

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Targeting of NEDD8 and its conjugates for proteasomal degradation by NUB1

21 January 2018

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NUB1, a NEDD8-interacting protein, is induced by interferon and down-regulates the NEDD8 expression

21 January 2018

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Interaction of NUB1 with the proteasome subunit S5a.

21 January 2018

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The UBA domains of NUB1L are required for binding but not for accelerated degradation of the ubiquitin-like modifier FAT10

21 January 2018

1 reference

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FAT10 and NUB1L bind to the VWA domain of Rpn10 and Rpn1 to enable proteasome-mediated proteolysis.

21 January 2018

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DNA-protein kinase catalytic subunit-interacting protein KIP binds telomerase by interacting with human telomerase reverse transcriptase

21 January 2018

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Structural basis of selective ubiquitination of TRF1 by SCFFbx4

21 January 2018

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Phosphorylation and ubiquitination-dependent degradation of CABIN1 releases p53 for transactivation upon genotoxic stress

21 January 2018

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The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor

21 January 2018

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Identification of human Rap1: implications for telomere evolution

21 January 2018

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An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

21 January 2018

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Crystal structure of the human ubiquitin-like protein NEDD8 and interactions with ubiquitin pathway enzymes

21 January 2018

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A targeted proteomic analysis of the ubiquitin-like modifier nedd8 and associated proteins.

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1002/1873-3468.12221

1 reference

14 February 2017

1 reference