(Q29013238)

2 August 2017

1 reference

title

Mammalian G1- and S-phase checkpoints in response to DNA damage (English)

2 references

https://doi.org/10.1016%2FS0955-0674%2800%2900280-5

23 March 2017

2 August 2017

0 references

2

Jiri Lukas

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Jiří Bártek

series ordinal

1

object named as

Jiri Bartek

0 references

language of work or name

1 reference

1 December 2001

1 reference

Current Opinion in Cell Biology

2 August 2017

2 references

https://doi.org/10.1016%2FS0955-0674%2800%2900280-5

23 March 2017

2 August 2017

13

2 references

https://doi.org/10.1016%2FS0955-0674%2800%2900280-5

23 March 2017

2 August 2017

738-747

2 references

https://doi.org/10.1016%2FS0955-0674%2800%2900280-5

23 March 2017

2 August 2017

6

2 references

https://doi.org/10.1016%2FS0955-0674%2800%2900280-5

23 March 2017

Genome maintenance mechanisms for preventing cancer

2 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Human DNA repair genes

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Cell cycle control and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

The DNA damage response: putting checkpoints in perspective

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

The many substrates and functions of ATM

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

DNA double-strand breaks: signaling, repair and the cancer connection

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

ATM and ATR: networking cellular responses to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme?

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

The Mre11 complex and ATM: collaborating to navigate S phase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Pathways governing G1/S transition and their response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Rapid destruction of human Cdc25A in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Reconstitution of an ATM-dependent checkpoint that inhibits chromosomal DNA replication following DNA damage.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

ATM-dependent phosphorylation of nibrin in response to radiation exposure

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

The retinoblastoma protein pathway and the restriction point

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Involvement of Myc activity in a G(1)/S-promoting mechanism parallel to the pRb/E2F pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

CDK inhibitors: positive and negative regulators of G1-phase progression

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

The Rb/E2F pathway: expanding roles and emerging paradigms

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Regulation of G(1) cyclin-dependent kinases in the mammalian cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Control of chromosomal DNA replication in the early Xenopus embryo

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Accumulation of cyclin E is not a prerequisite for passage through the restriction point

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

pRB plays an essential role in cell cycle arrest induced by DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Regulation and function of the p53 tumor suppressor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Caffeine inhibits the checkpoint kinase ATM

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Distinct Initiation and Maintenance Mechanisms Cooperate to Induce G1 Cell Cycle Arrest in Response to DNA Damage

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

p53 binds selectively to the 5' untranslated region of cdk4, an RNA element necessary and sufficient for transforming growth factor beta- and p53-mediated translational inhibition of cdk4.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

p53 is associated with cellular microtubules and is transported to the nucleus by dynein

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

1 reference

7 January 2021

Differential requirement for p19ARF in the p53-dependent arrest induced by DNA damage, microtubule disruption, and ribonucleotide depletion

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

DNA replication: building the perfect switch

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

p53 accumulates but is functionally impaired when DNA synthesis is blocked

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

1 reference

7 January 2021

Radiation down-regulates replication origin activity throughout the S phase in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Distinct functional domains of nibrin mediate Mre11 binding, focus formation, and nuclear localization

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

New link in a web of human genes

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Mre11 complex and DNA replication: linkage to E2F and sites of DNA synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

In search of the tumour-suppressor functions of BRCA1 and BRCA2

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Cell cycle. Piecing together the p53 puzzle.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Human Cdc25 A inactivation in response to S phase inhibition and its role in preventing premature mitosis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

CHK1 frameshift mutations in genetically unstable colorectal and endometrial cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Chk2 tumour suppressor protein in human spermatogenesis and testicular germ-cell tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Functional impact of concomitant versus alternative defects in the Chk2-p53 tumour suppressor pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Role of the Cdc25A phosphatase in human breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Specific protection against breast cancers by cyclin D1 ablation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

Cell cycle checkpoint signaling through the ATM and ATR kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900280-5

7 January 2021

10.1016/S0955-0674(00)00280-5

Identifiers

DOI

2 references

https://doi.org/10.1016%2FS0955-0674%2800%2900280-5

23 March 2017

2 August 2017

1 reference

PubMed ID

11698191