(Q29305058)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343901%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

title

IDH mutation impairs histone demethylation and results in a block to cell differentiation (English)

2 references

9 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343901%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343901%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Sevin Turcan

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343901%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Omar Abdel-Wahab

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343901%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Maria E Figueroa

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343901%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Donald M O'Rourke

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343901%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Shelley L. Berger

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343901%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Ingo K Mellinghoff

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343901%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

17

Craig B Thompson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343901%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

author name string

Chao Lu

1

2 references

9 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343901%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Dan Rohle

4

2 references

9 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343901%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Raya Khanin

8

2 references

9 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343901%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Ari Melnick

10

2 references

9 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343901%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Gurpreet S Kapoor

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343901%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Christopher R Edwards

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343901%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Kathryn E Wellen

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343901%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Timothy A Chan

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343901%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Ross L Levine

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343901%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

language of work or name

English

0 references

publication date

15 February 2012

2 references

9 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343901%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

2 references

9 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343901%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

volume

483

2 references

9 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343901%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

page(s)

474-478

2 references

9 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343901%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

issue

7390

2 references

9 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343901%20AND%20SRC:MED&resulttype=core&format=json

Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain

23 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

Recurring mutations found by sequencing an acute myeloid leukemia genome

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

IDH1 and IDH2 mutations in gliomas

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

An integrated genomic analysis of human glioblastoma multiforme

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

The complex language of chromatin regulation during transcription

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

A bivalent chromatin structure marks key developmental genes in embryonic stem cells

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

ATP-citrate lyase links cellular metabolism to histone acetylation

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

MLL translocations, histone modifications and leukaemia stem-cell development

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours

9 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell state

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

Genome-wide epigenetic analysis delineates a biologically distinct immature acute leukemia with myeloid/T-lymphoid features.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

Analysis of the IDH1 codon 132 mutation in brain tumors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

Histone H3 K4 demethylation during activation and attenuation of GAL1 transcription in Saccharomyces cerevisiae.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

A novel nuclear protein, 5qNCA (LOC51780) is a candidate for the myeloid leukemia tumor suppressor gene on chromosome 5 band q31.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

DNA global hypomethylation in EBV-transformed interphase nuclei

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

Transcriptional regulation of gene expression during adipocyte differentiation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

Development of hormone receptors and hormonal responsiveness in vitro. Insulin receptors and insulin sensitivity in the preadipocyte and adipocyte forms of 3T3-L1 cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

Formation of intracranial tumors by genetically modified human astrocytes defines four pathways critical in the development of human anaplastic astrocytoma

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478770

26 November 2018

Identifiers

DOI

10.1038/NATURE10860

3 references

9 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343901%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

23 January 2020

1000103968

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343901%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22343901%20AND%20SRC:MED&resulttype=core&format=json