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An extensive network of coupling among gene expression machines
scientific article (publication date: 4 April 2002)
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An extensive network of coupling among gene expression machines
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Maniatis T
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23 April 2017
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Allosteric interactions between capping enzyme subunits and the RNA polymerase II carboxy-terminal domain
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Interaction between P-TEFb and the C-terminal domain of RNA polymerase II activates transcriptional elongation from sites upstream or downstream of target genes
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Positive transcription elongation factor B phosphorylates hSPT5 and RNA polymerase II carboxyl-terminal domain independently of cyclin-dependent kinase-activating kinase.
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Transcription elongation factor hSPT5 stimulates mRNA capping
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Stimulatory effect of splicing factors on transcriptional elongation
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NF-kappaB binds P-TEFb to stimulate transcriptional elongation by RNA polymerase II.
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Tat-SF1 protein associates with RAP30 and human SPT5 proteins
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CUS2, a yeast homolog of human Tat-SF1, rescues function of misfolded U2 through an unusual RNA recognition motif
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A human RNA polymerase II-containing complex associated with factors necessary for spliceosome assembly
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A CTD function linking transcription to splicing
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The splicing factor, Prp40, binds the phosphorylated carboxyl-terminal domain of RNA polymerase II.
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Cross-intron bridging interactions in the yeast commitment complex are conserved in mammals
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A novel transcriptional coactivator, p52, functionally interacts with the essential splicing factor ASF/SF2
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Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1
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SR proteins are 'locators' of the RNA splicing machinery
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Coupling of transcription with alternative splicing: RNA pol II promoters modulate SF2/ASF and 9G8 effects on an exonic splicing enhancer
1 reference
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7 January 2021
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inferred from DOI database lookup
Antagonistic effects of T-Ag and VP16 reveal a role for RNA pol II elongation on alternative splicing
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Crossref
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7 January 2021
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inferred from DOI database lookup
Effects of RNA secondary structure on alternative splicing of Pre-mRNA: Is folding limited to a region behind the transcribing RNA polymerase?
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7 January 2021
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inferred from DOI database lookup
Co-transcriptional commitment to alternative splice site selection.
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
A nuclear cap-binding complex facilitates association of U1 snRNP with the cap-proximal 5' splice site.
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
The yeast splicing factor Mud13p is a commitment complex component and corresponds to CBP20, the small subunit of the nuclear cap-binding complex
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
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7 January 2021
based on heuristic
inferred from DOI database lookup
SRm160 splicing coactivator promotes transcript 3'-end cleavage
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of fidelity in pre-mRNA splicing
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
How RNA polymerase II terminates transcription in higher eukaryotes
1 reference
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7 January 2021
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inferred from DOI database lookup
Coupling termination of transcription to messenger RNA maturation in yeast.
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Role of RNA polymerase II carboxy-terminal domain in coordinating transcription with RNA processing
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple transcript cleavage precedes polymerase release in termination by RNA polymerase II
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
EM visualization of transcription by RNA polymerase II: downstream termination requires a poly(A) signal but not transcript cleavage.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of poly(A) signal transduction to RNA polymerase II in vitro
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional termination factors for RNA polymerase II in yeast
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evolutionarily conserved interaction between CstF-64 and PC4 links transcription, polyadenylation, and termination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inefficient processing impairs release of RNA from the site of transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A block to mRNA nuclear export in S. cerevisiae leads to hyperadenylation of transcripts that accumulate at the site of transcription
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role for Cajal bodies in assembly of the nuclear transcription machinery
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional architecture in the cell nucleus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Newly assembled snRNPs associate with coiled bodies before speckles, suggesting a nuclear snRNP maturation pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The dynamics of a pre-mRNA splicing factor in living cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Serine phosphorylation of SR proteins is required for their recruitment to sites of transcription in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RNA polymerase II targets pre-mRNA splicing factors to transcription sites in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High mobility of proteins in the mammalian cell nucleus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The organization of replication and transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In situ transcription and splicing in the Balbiani ring 3 gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Splicing is required for rapid and efficient mRNA export in metazoans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Splicing factor Sub2p is required for nuclear mRNA export through its interaction with Yra1p
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The DExH/D box protein HEL/UAP56 is essential for mRNA nuclear export in Drosophila
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pre-mRNA splicing imprints mRNA in the nucleus with a novel RNA-binding protein that persists in the cytoplasm
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPS1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Y14 protein communicates to the cytoplasm the position of exon-exon junctions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mex67p, a novel factor for nuclear mRNA export, binds to both poly(A)+ RNA and nuclear pores
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The DECD box putative ATPase Sub2p is an early mRNA export factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A new view of mRNA export: separating the wheat from the chaff
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Splicing factors SRp20 and 9G8 promote the nucleocytoplasmic export of mRNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Quality control of mRNA 3'-end processing is linked to the nuclear exosome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Messenger RNAs are recruited for nuclear export during transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rna15 interaction with the A-rich yeast polyadenylation signal is an essential step in mRNA 3'-end formation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hrp1, a sequence-specific RNA-binding protein that shuttles between the nucleus and the cytoplasm, is required for mRNA 3'-end formation in yeast
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The yeast hnRNP-like protein Hrp1/Nab4 marks a transcript for nonsense-mediated mRNA decay
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Quality control of mRNA function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A perfect message: RNA surveillance and nonsense-mediated decay
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Precursor RNAs harboring nonsense codons accumulate near the site of transcription.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Should we kill the messenger? The role of the surveillance complex in translation termination and mRNA turnover
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F416499A
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/416499A
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11932736
retrieved
23 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1379472
Dimensions Publication ID
1030329468
0 references
OpenCitations bibliographic resource ID
1379472
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1379472
PubMed ID
11932736
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11932736
retrieved
23 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1379472
ResearchGate publication ID
11432425
0 references
Springer Nature article ID
10.1038/416499a
0 references
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