(Q29615368)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17957188%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

review article

1 reference

title

MLL translocations, histone modifications and leukaemia stem-cell development (English)

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17957188

30 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17957188%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

1

1 reference

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9 January 2020

author name string

Scott A Armstrong

series ordinal

2

1 reference

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9 January 2020

language of work or name

1 reference

30 April 2017

publication date

1 November 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17957188%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

published in

Nature Reviews Cancer

2 references

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30 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17957188%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

volume

7

2 references

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30 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17957188%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

page(s)

823-833

1 reference

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9 January 2020

issue

11

2 references

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30 April 2017

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Translating the Histone Code

9 January 2020

cites work

1 reference

Histone methylation versus histone acetylation: new insights into epigenetic regulation

31 March 2020

1 reference

Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expression

31 March 2020

1 reference

Polycomb silencers control cell fate, development and cancer

31 March 2020

1 reference

Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins

31 March 2020

1 reference

An atlas of chromosomes in hematological malignancies. Example: 11q23 and MLL partners

31 March 2020

1 reference

The MLL recombinome of acute leukemias

31 March 2020

1 reference

Attitudes of terminally ill cancer patients about euthanasia and assisted suicide: predominance of psychosocial determinants and beliefs over symptom distress and subsequent survival.

31 March 2020

1 reference

The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene

31 March 2020

1 reference

Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

31 March 2020

1 reference

Expression of HOX genes, HOX cofactors, and MLL in phenotypically and functionally defined subpopulations of leukemic and normal human hematopoietic cells

31 March 2020

1 reference

The genetic program of hematopoietic stem cells

31 March 2020

1 reference

Extending the repertoire of the mixed-lineage leukemia gene MLL in leukemogenesis

31 March 2020

1 reference

MLL: how complex does it get?

31 March 2020

1 reference

MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein

31 March 2020

1 reference

Histone H3 lysine 4 methylation is mediated by Set1 and required for cell growth and rDNA silencing in Saccharomyces cerevisiae

31 March 2020

1 reference

MLL targets SET domain methyltransferase activity to Hox gene promoters

31 March 2020

1 reference

Regulation of MLL1 H3K4 methyltransferase activity by its core components

31 March 2020

1 reference

Molecular regulation of H3K4 trimethylation by ASH2L, a shared subunit of MLL complexes

31 March 2020

1 reference

Molecular recognition of histone H3 by the WD40 protein WDR5.

31 March 2020

1 reference

MLL core components give the green light to histone methylation.

31 March 2020

1 reference

Histone H3 Lys 4 methylation: caught in a bind?

31 March 2020

1 reference

ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation

31 March 2020

1 reference

Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression

31 March 2020

1 reference

Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF

31 March 2020

1 reference

11q23 translocations split the "AT-hook" cruciform DNA-binding region and the transcriptional repression domain from the activation domain of the mixed-lineage leukemia (MLL) gene

31 March 2020

1 reference

The MT domain of the proto-oncoprotein MLL binds to CpG-containing DNA and discriminates against methylation

31 March 2020

1 reference

The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis

31 March 2020

1 reference

MLL repression domain interacts with histone deacetylases, the polycomb group proteins HPC2 and BMI-1, and the corepressor C-terminal-binding protein

31 March 2020

1 reference

Hox regulation of normal and leukemic hematopoietic stem cells.

31 March 2020

1 reference

Altered Hox expression and segmental identity in Mll-mutant mice

31 March 2020

1 reference

Histone and DNA methylation defects at Hox genes in mice expressing a SET domain-truncated form of Mll.

31 March 2020

1 reference

Mammalian Trithorax and polycomb-group homologues are antagonistic regulators of homeotic development

31 March 2020

1 reference

Global and Hox-specific roles for the MLL1 methyltransferase

31 March 2020

1 reference

Definitive hematopoiesis requires the mixed-lineage leukemia gene

31 March 2020

1 reference

Stem cell self-renewal and cancer cell proliferation are regulated by common networks that balance the activation of proto-oncogenes and tumor suppressors.

31 March 2020

1 reference

Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

31 March 2020

1 reference

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

31 March 2020

1 reference

MLL associates specifically with a subset of transcriptionally active target genes

31 March 2020

1 reference

Frequent chromosomal translocations induced by DNA double-strand breaks

31 March 2020

1 reference

Dimerization contributes to oncogenic activation of MLL chimeras in acute leukemias

31 March 2020

1 reference

Common mechanism for oncogenic activation of MLL by forkhead family proteins

31 March 2020

1 reference

The pathobiology of the septin gene family

31 March 2020

1 reference

ALL-1 partial duplication in acute leukemia

31 March 2020

1 reference

The oncogenic capacity of HRX-ENL requires the transcriptional transactivation activity of ENL and the DNA binding motifs of HRX.

31 March 2020

1 reference

Leukemogenic MLL fusion proteins bind across a broad region of the Hox a9 locus, promoting transcription and multiple histone modifications.

31 March 2020

1 reference

An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: a method to create fusion oncogenes

31 March 2020

1 reference

Inter-chromosomal recombination of Mll and Af9 genes mediated by cre-loxP in mouse development.

31 March 2020

1 reference

Engineering de novo reciprocal chromosomal translocations associated with Mll to replicate primary events of human cancer

31 March 2020

1 reference

Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease.

31 March 2020

1 reference

A murine Mll-AF4 knock-in model results in lymphoid and myeloid deregulation and hematologic malignancy

31 March 2020

1 reference

A conditional model of MLL-AF4 B-cell tumourigenesis using invertor technology

31 March 2020

1 reference

Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL.

31 March 2020

1 reference

MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice

31 March 2020

1 reference

The oncoprotein MLL-ENL disturbs hematopoietic lineage determination and transforms a biphenotypic lymphoid/myeloid cell

31 March 2020

1 reference

Modeling the initiation and progression of human acute leukemia in mice

31 March 2020

1 reference

The partial tandem duplication of ALL1 in acute myeloid leukemia with normal cytogenetics or trisomy 11 is restricted to one chromosome

31 March 2020

1 reference

Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations

31 March 2020

1 reference

Tumorigenesis in mice with a fusion of the leukaemia oncogene Mll and the bacterial lacZ gene.

31 March 2020

1 reference

Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors

31 March 2020

1 reference

When epigenetics kills: MLL fusion proteins in leukemia

31 March 2020

1 reference

An RNA polymerase II elongation factor encoded by the human ELL gene

31 March 2020

1 reference

EAF1, a novel ELL-associated factor that is delocalized by expression of the MLL-ELL fusion protein

31 March 2020

1 reference

ENL, the MLL fusion partner in t(11;19), binds to the c-Abl interactor protein 1 (ABI1) that is fused to MLL in t(10;11)+.

31 March 2020

1 reference

Domains with transcriptional regulatory activity within the ALL1 and AF4 proteins involved in acute leukemia

31 March 2020

1 reference

MLL-AFX requires the transcriptional effector domains of AFX to transform myeloid progenitors and transdominantly interfere with forkhead protein function

31 March 2020

1 reference

MLL fusion partners AF4 and AF9 interact at subnuclear foci

31 March 2020

1 reference

hDOT1L links histone methylation to leukemogenesis

31 March 2020

1 reference

A chromatin landmark and transcription initiation at most promoters in human cells

31 March 2020

1 reference

An epigenetic road map for histone lysine methylation

31 March 2020

1 reference

Dot1a-AF9 complex mediates histone H3 Lys-79 hypermethylation and repression of ENaCalpha in an aldosterone-sensitive manner

31 March 2020

1 reference

The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling

31 March 2020

1 reference

The eleven-nineteen-leukemia protein ENL connects nuclear MLL fusion partners with chromatin

31 March 2020

1 reference

The interaction between EEN and Abi-1, two MLL fusion partners, and synaptojanin and dynamin: implications for leukaemogenesis

31 March 2020

1 reference

31 March 2020

1 reference

Myeloerythroid-restricted progenitors are sufficient to confer radioprotection and provide the majority of day 8 CFU-S.

31 March 2020

1 reference

MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors.

31 March 2020

1 reference

moz regulates Hox expression and pharyngeal segmental identity in zebrafish

31 March 2020

1 reference

MOZ-TIF2-induced acute myeloid leukemia requires the MOZ nucleosome binding motif and TIF2-mediated recruitment of CBP.

31 March 2020

1 reference

Biology of normal and acute myeloid leukemia stem cells

31 March 2020

1 reference

Stem cells, cancer, and cancer stem cells

31 March 2020

1 reference

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

31 March 2020

1 reference

Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates

31 March 2020

1 reference

Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.

31 March 2020

1 reference

Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia.

31 March 2020

1 reference

Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b

31 March 2020

1 reference

Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells.

31 March 2020

1 reference

Gene expression analysis of purified hematopoietic stem cells and committed progenitors

31 March 2020

1 reference

The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors

31 March 2020

1 reference

Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

31 March 2020

1 reference

Requirement for CD44 in homing and engraftment of BCR-ABL-expressing leukemic stem cells

31 March 2020

1 reference

Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia

31 March 2020

1 reference

Targeting of CD44 eradicates human acute myeloid leukemic stem cells

31 March 2020

1 reference

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

31 March 2020

1 reference

Generation of germline-competent induced pluripotent stem cells

31 March 2020

1 reference

In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state

31 March 2020

1 reference

Epigenetic aberrations and cancer

31 March 2020

1 reference

Phenotypic plasticity and the epigenetics of human disease

31 March 2020

1 reference

Cancer epigenomics: DNA methylomes and histone-modification maps

31 March 2020

1 reference

Chromatin compaction by a polycomb group protein complex

31 March 2020

1 reference

Histone trimethylation and the maintenance of transcriptional ON and OFF states by trxG and PcG proteins

31 March 2020

1 reference

Genome regulation by polycomb and trithorax proteins

31 March 2020

1 reference

Protein interactions of the MLL PHD fingers modulate MLL target gene regulation in human cells

31 March 2020

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17957188

31 March 2020

Identifiers

3 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017

686537

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17957188%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 January 2020

1035045408

0 references

686537

1 reference

Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17957188

3 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017

686537

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17957188%20AND%20SRC:MED&resulttype=core&format=json