(Q29617411)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24336569%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

title

Genetic screens in human cells using the CRISPR-Cas9 system (English)

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=24336569

30 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24336569%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

0 references

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24336569%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

David M. Sabatini

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24336569%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

4

Eric S Lander

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24336569%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

author name string

Jenny J Wei

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24336569%20AND%20SRC:MED&resulttype=core&format=json

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=24336569

3 March 2020

language of work or name

1 reference

30 April 2017

publication date

12 December 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24336569%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=24336569

30 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24336569%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

volume

343

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=24336569

30 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24336569%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

page(s)

80-84

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24336569%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

issue

6166

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=24336569

30 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24336569%20AND%20SRC:MED&resulttype=core&format=json

on focus list of Wikimedia project

3 March 2020

ScienceSource

0 references

cites work

Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

DNA targeting specificity of RNA-guided Cas9 nucleases

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

Efficient genome editing in zebrafish using a CRISPR-Cas system

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

RNA-guided human genome engineering via Cas9

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

Multiplex genome engineering using CRISPR/Cas systems

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

The genetic landscape of a cell

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

Haploid genetic screens in human cells identify host factors used by pathogens

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

Topoisomerase levels determine chemotherapy responsein vitroandin vivo

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

Functional profiling of the Saccharomyces cerevisiae genome

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

A system for stable expression of short interfering RNAs in mammalian cells

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

Eukaryotic DNA mismatch repair

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

Fast gapped-read alignment with Bowtie 2

30 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1246981

Identification and characterization of a novel gene, c1orf109, encoding a CK2 substrate that is involved in cancer cell proliferation

1 May 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1246981

Codanin-1 mutations in congenital dyserythropoietic anemia type 1 affect HP1{alpha} localization in erythroblasts

1 May 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1246981

The THAP-zinc finger protein THAP1 regulates endothelial cell proliferation through modulation of pRB/E2F cell-cycle target genes

1 May 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1246981

Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans

1 May 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1246981

Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library

1 May 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1246981

Generation of an ICF syndrome model by efficient genome editing of human induced pluripotent stem cells using the CRISPR system

1 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

Complex DNA repair pathways as possible therapeutic targets to overcome temozolomide resistance in glioblastoma

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

Specialized ribosomes: a new frontier in gene regulation and organismal biology

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

False negative rates in Drosophila cell-based RNAi screens: a case study

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

Large-scale population study of human cell lines indicates that dosage compensation is virtually complete

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

A loss-of-function RNA interference screen for molecular targets in cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

Mismatch repair genes identified using genetic screens in Blm-deficient embryonic stem cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

Changes associated with the development of resistance to imatinib (STI571) in two leukemia cell lines expressing p210 Bcr/Abl protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

DNA mismatch repair (MMR) mediates 6-thioguanine genotoxicity by introducing single-strand breaks to signal a G2-M arrest in MMR-proficient RKO cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

Molecular biology. Use and abuse of RNAi to study mammalian gene function

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

Minimizing the risk of reporting false positives in large-scale RNAi screens

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3972032

26 November 2018

Identifiers

DOI

10.1126/SCIENCE.1246981

3 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=24336569

30 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24336569%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=24336569

3 references

30 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24336569%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

3 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=24336569

30 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24336569%20AND%20SRC:MED&resulttype=core&format=json