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Recognition of microorganisms and activation of the immune response
scientific article (publication date: 18 October 2007)
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Recognition of microorganisms and activation of the immune response
(English)
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Medzhitov R
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30 April 2017
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English
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publication date
18 October 2007
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published in
Nature
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449
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30 April 2017
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819-26
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PubMed
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7164
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30 April 2017
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Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
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Pathogen recognition and innate immunity
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Induction of direct antimicrobial activity through mammalian toll-like receptors
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Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response
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Immune recognition. A new receptor for beta-glucans
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Myeloid C-type lectins in innate immunity
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Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17
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Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans
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Dectin-1 is required for beta-glucan recognition and control of fungal infection
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Dectin-1: a signalling non-TLR pattern-recognition receptor
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Nod-like proteins in immunity, inflammation and disease
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NOD-LRR proteins: role in host-microbial interactions and inflammatory disease
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Intracellular pattern recognition receptors in the host response
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CATERPILLER: a novel gene family important in immunity, cell death, and diseases
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Nod1-Mediated Innate Immune Recognition of Peptidoglycan Contributes to the Onset of Adaptive Immunity
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Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
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NOD2 and Crohn's disease: loss or gain of function?
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Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases
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The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
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DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
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Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus
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5'-Triphosphate RNA is the ligand for RIG-I
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Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
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RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates
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Antiviral innate immunity pathways.
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A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA.
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Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation
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Recognition of cytosolic DNA activates an IRF3-dependent innate immune response
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Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors
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Autoreactivity by design: innate B and T lymphocytes
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Origins and functions of B-1 cells with notes on the role of CD5
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Patterns of nonclassical MHC antigen presentation
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Specificity and function of T cells bearing gamma delta receptors
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Crossref
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7 January 2021
based on heuristic
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Pentraxins as a key component of innate immunity
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Crossref
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https://api.crossref.org/works/10.1038%2FNATURE06246
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7 January 2021
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Lectin complement system and pattern recognition
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Crossref
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7 January 2021
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Collections and ficolins: humoral lectins of the innate immune defense
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Crossref
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https://api.crossref.org/works/10.1038%2FNATURE06246
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7 January 2021
based on heuristic
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Complement and the immune response
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Crossref
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https://api.crossref.org/works/10.1038%2FNATURE06246
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7 January 2021
based on heuristic
inferred from DOI database lookup
NK cell recognition
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNATURE06246
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7 January 2021
based on heuristic
inferred from DOI database lookup
Diverse functions of IL-2, IL-15, and IL-7 in lymphoid homeostasis
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Crossref
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https://api.crossref.org/works/10.1038%2FNATURE06246
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7 January 2021
based on heuristic
inferred from DOI database lookup
Triggering the innate antiviral response through IRF-3 activation
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNATURE06246
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7 January 2021
based on heuristic
inferred from DOI database lookup
IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNATURE06246
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mast cells in the development of adaptive immune responses
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNATURE06246
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7 January 2021
based on heuristic
inferred from DOI database lookup
Chitin induces accumulation in tissue of innate immune cells associated with allergy
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNATURE06246
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7 January 2021
based on heuristic
inferred from DOI database lookup
Th2 cells: orchestrating barrier immunity
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNATURE06246
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7 January 2021
based on heuristic
inferred from DOI database lookup
Toll-dependent selection of microbial antigens for presentation by dendritic cells
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Crossref
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https://api.crossref.org/works/10.1038%2FNATURE06246
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7 January 2021
based on heuristic
inferred from DOI database lookup
Dendritic cells and the control of immunity
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Crossref
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https://api.crossref.org/works/10.1038%2FNATURE06246
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7 January 2021
based on heuristic
inferred from DOI database lookup
T helper cell effector fates--who, how and where?
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Crossref
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https://api.crossref.org/works/10.1038%2FNATURE06246
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7 January 2021
based on heuristic
inferred from DOI database lookup
Acquisition of lymphokine-producing phenotype by CD4+ T cells
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNATURE06246
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7 January 2021
based on heuristic
inferred from DOI database lookup
The IL-4 receptor: signaling mechanisms and biologic functions
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNATURE06246
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7 January 2021
based on heuristic
inferred from DOI database lookup
IL-17 family cytokines and the expanding diversity of effector T cell lineages
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNATURE06246
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7 January 2021
based on heuristic
inferred from DOI database lookup
Development in motion: helper T cells at work
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNATURE06246
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7 January 2021
based on heuristic
inferred from DOI database lookup
Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNATURE06246
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7 January 2021
based on heuristic
inferred from DOI database lookup
TSLP: an epithelial cell cytokine that regulates T cell differentiation by conditioning dendritic cell maturation
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNATURE06246
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7 January 2021
based on heuristic
inferred from DOI database lookup
Coordinated and distinct roles for IFN-alpha beta, IL-12, and IL-15 regulation of NK cell responses to viral infection
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06246
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7 January 2021
based on heuristic
inferred from DOI database lookup
Helper T cells regulate type-2 innate immunity in vivo
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNATURE06246
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7 January 2021
based on heuristic
inferred from DOI database lookup
Studies in listeriosis show the strong symbiosis between the innate cellular system and the T-cell response
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNATURE06246
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7 January 2021
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Identifiers
DOI
10.1038/NATURE06246
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17943118
retrieved
30 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
241998
Dimensions Publication ID
1004311589
0 references
OpenCitations bibliographic resource ID
241998
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
241998
PubMed ID
17943118
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17943118
retrieved
30 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
241998
ResearchGate publication ID
5902741
0 references
Springer Nature article ID
10.1038/nature06246
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