(Q29619893)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12154370%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

review article

1 reference

title

ERM proteins and merlin: integrators at the cell cortex (English)

2 references

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30 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12154370%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference

2

1 reference

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11 November 2019

3

Richard G Fehon

1 reference

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11 November 2019

author name string

Anthony Bretscher

series ordinal

1

1 reference

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11 November 2019

language of work or name

1 reference

30 April 2017

publication date

1 August 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12154370%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Molecular Cell Biology

11 November 2019

published in

2 references

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30 April 2017

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11 November 2019

volume

3

2 references

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30 April 2017

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11 November 2019

page(s)

586-599

1 reference

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11 November 2019

issue

8

2 references

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30 April 2017

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Purification of an 80,000-dalton protein that is a component of the isolated microvillus cytoskeleton, and its localization in nonmuscle cells

11 November 2019

cites work

1 reference

Microvillus-specific Mr 75,000 plasma membrane protein of human choriocarcinoma cells

31 March 2020

1 reference

The protein-tyrosine kinase substrate, p81, is homologous to a chicken microvillar core protein

31 March 2020

1 reference

A new 82-kD barbed end-capping protein (radixin) localized in the cell-to-cell adherens junction: purification and characterization

31 March 2020

1 reference

Radixin is a component of hepatocyte microvilli in situ

31 March 2020

1 reference

A heparin-binding protein involved in inhibition of smooth-muscle cell proliferation

31 March 2020

1 reference

cDNA cloning and sequencing of the protein-tyrosine kinase substrate, ezrin, reveals homology to band 4.1

31 March 2020

1 reference

Moesin: a member of the protein 4.1-talin-ezrin family of proteins

31 March 2020

1 reference

Radixin is a novel member of the band 4.1 family

31 March 2020

1 reference

A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor.

31 March 2020

1 reference

Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2

31 March 2020

1 reference

ERM-Merlin and EBP50 protein families in plasma membrane organization and function

31 March 2020

1 reference

ERM proteins in cell adhesion and membrane dynamics

31 March 2020

1 reference

Cortical actin organization: lessons from ERM (ezrin/radixin/moesin) proteins

31 March 2020

1 reference

Normal development of mice and unimpaired cell adhesion/cell motility/actin-based cytoskeleton without compensatory up-regulation of ezrin or radixin in moesin gene knockout

31 March 2020

1 reference

Perturbation of cell adhesion and microvilli formation by antisense oligonucleotides to ERM family members

31 March 2020

1 reference

ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse

31 March 2020

1 reference

Identification of a 55-kDa ezrin-related protein that induces cytoskeletal changes and localizes to the nucleolus

31 March 2020

1 reference

Ezrin is an effector of hepatocyte growth factor-mediated migration and morphogenesis in epithelial cells

31 March 2020

1 reference

The Nf2 tumor suppressor gene product is essential for extraembryonic development immediately prior to gastrulation

31 March 2020

1 reference

Neurofibromatosis 2: loss of merlin's protective spell

31 March 2020

1 reference

Heterotypic and homotypic associations between ezrin and moesin, two putative membrane-cytoskeletal linking proteins

31 March 2020

1 reference

Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site

31 March 2020

1 reference

Ezrin oligomers are major cytoskeletal components of placental microvilli: a proposal for their involvement in cortical morphogenesis.

31 March 2020

1 reference

Soluble ezrin purified from placenta exists as stable monomers and elongated dimers with masked C-terminal ezrin-radixin-moesin association domains

31 March 2020

1 reference

Interdomain interactions of radixin in vitro

31 March 2020

1 reference

Ezrin NH2-terminal domain inhibits the cell extension activity of the COOH-terminal domain

31 March 2020

1 reference

Molecular dissection of radixin: distinct and interdependent functions of the amino- and carboxy-terminal domains

31 March 2020

1 reference

The carboxyl-terminal region of EBP50 binds to a site in the amino-terminal domain of ezrin that is masked in the dormant molecule.

31 March 2020

1 reference

Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/moesin initiates the activation of the Rho small G protein

31 March 2020

1 reference

Structural conversion between open and closed forms of radixin: low-angle shadowing electron microscopy.

31 March 2020

1 reference

Morphogenic effects of ezrin require a phosphorylation-induced transition from oligomers to monomers at the plasma membrane

31 March 2020

1 reference

Phosphorylation of threonine 558 in the carboxyl-terminal actin-binding domain of moesin by thrombin activation of human platelets

31 March 2020

1 reference

Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association

31 March 2020

1 reference

Phosphorylation of moesin by rho-associated kinase (Rho-kinase) plays a crucial role in the formation of microvilli-like structures

31 March 2020

1 reference

Ezrin function is required for ROCK-mediated fibroblast transformation by the Net and Dbl oncogenes

31 March 2020

1 reference

Ezrin is a downstream effector of trafficking PKC-integrin complexes involved in the control of cell motility

31 March 2020

1 reference

Protein kinase C-theta phosphorylation of moesin in the actin-binding sequence

31 March 2020

1 reference

C-terminal threonine phosphorylation activates ERM proteins to link the cell's cortical lipid bilayer to the cytoskeleton

31 March 2020

1 reference

Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway

31 March 2020

1 reference

Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2

31 March 2020

1 reference

Regulation of F-actin binding to platelet moesin in vitro by both phosphorylation of threonine 558 and polyphosphatidylinositides

31 March 2020

1 reference

Identification of a phosphatidylinositol-4,5-bisphosphate-binding domain in the N-terminal region of ezrin

31 March 2020

1 reference

Mutagenesis of the phosphatidylinositol 4,5-bisphosphate (PIP(2)) binding site in the NH(2)-terminal domain of ezrin correlates with its altered cellular distribution

31 March 2020

1 reference

Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain

31 March 2020

1 reference

Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain

31 March 2020

1 reference

The 2.7 A crystal structure of the activated FERM domain of moesin: an analysis of structural changes on activation

31 March 2020

1 reference

Unexpected effects of FERM domain mutations on catalytic activity of Jak3: structural implication for Janus kinases

31 March 2020

1 reference

The properties of the protein tyrosine phosphatase PTPMEG.

31 March 2020

1 reference

F-actin binding site masked by the intramolecular association of vinculin head and tail domains

31 March 2020

1 reference

Actin activates a cryptic dimerization potential of the vinculin tail domain

31 March 2020

1 reference

The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly

31 March 2020

1 reference

Identification of a carboxyl-terminal diaphanous-related formin homology protein autoregulatory domain

31 March 2020

1 reference

Rapid phosphorylation and reorganization of ezrin and spectrin accompany morphological changes induced in A-431 cells by epidermal growth factor

31 March 2020

1 reference

Ezrin has a COOH-terminal actin-binding site that is conserved in the ezrin protein family

31 March 2020

1 reference

Moesin, ezrin, and p205 are actin-binding proteins associated with neutrophil plasma membranes

31 March 2020

1 reference

Identification of a novel member of the chloride intracellular channel gene family (CLIC5) that associates with the actin cytoskeleton of placental microvilli

31 March 2020

1 reference

A dual involvement of the amino-terminal domain of ezrin in F- and G-actin binding.

31 March 2020

1 reference

Three determinants in ezrin are responsible for cell extension activity

31 March 2020

1 reference

Stabilizing infrastructure of cell membranes

31 March 2020

1 reference

ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons

31 March 2020

1 reference

Identification and functional analysis of the ezrin-binding site in the hyaluronan receptor, CD44.

31 March 2020

1 reference

A novel PKC-regulated mechanism controls CD44 ezrin association and directional cell motility

31 March 2020

1 reference

Association of ezrin with intercellular adhesion molecule-1 and -2 (ICAM-1 and ICAM-2). Regulation by phosphatidylinositol 4, 5-bisphosphate

31 March 2020

1 reference

ICAM-2 redistributed by ezrin as a target for killer cells

31 March 2020

1 reference

31 March 2020

FERMing up the synapse.

1 reference

Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin

31 March 2020

1 reference

The membrane-microfilament linker ezrin is involved in the formation of the immunological synapse and in T cell activation

31 March 2020

1 reference

Direct binding of the Na--H exchanger NHE1 to ERM proteins regulates the cortical cytoskeleton and cell shape independently of H(+) translocation

31 March 2020

1 reference

NHE3 kinase A regulatory protein E3KARP binds the epithelial brush border Na+/H+ exchanger NHE3 and the cytoskeletal protein ezrin

31 March 2020

1 reference

Identification of EPI64, a TBC/rabGAP domain-containing microvillar protein that binds to the first PDZ domain of EBP50 and E3KARP

31 March 2020

1 reference

Signal complex regulation of renal transport proteins: NHERF and regulation of NHE3 by PKA.

31 March 2020

1 reference

New functions for the NHERF family of proteins

31 March 2020

1 reference

Ezrin binding domain-deficient NHERF attenuates cAMP-mediated inhibition of Na(+)/H(+) exchange in OK cells

31 March 2020

1 reference

Ezrin is a cyclic AMP-dependent protein kinase anchoring protein

31 March 2020

1 reference

Peptide binding consensus of the NHE-RF-PDZ1 domain matches the C-terminal sequence of cystic fibrosis transmembrane conductance regulator (CFTR)

31 March 2020

1 reference

An apical PDZ protein anchors the cystic fibrosis transmembrane conductance regulator to the cytoskeleton

31 March 2020

1 reference

A C-terminal motif found in the beta2-adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na+/H+ exchanger regulatory factor family of PDZ proteins

31 March 2020

1 reference

The beta2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange

31 March 2020

1 reference

A kinase-regulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptor

31 March 2020

1 reference

cAMP-mediated inhibition of the epithelial brush border Na+/H+ exchanger, NHE3, requires an associated regulatory protein

31 March 2020

1 reference

Platelet-derived growth factor receptor association with Na(+)/H(+) exchanger regulatory factor potentiates receptor activity

31 March 2020

1 reference

Loss of glomerular foot processes is associated with uncoupling of podocalyxin from the actin cytoskeleton

31 March 2020

1 reference

Activation of ERM proteins in vivo by Rho involves phosphatidyl-inositol 4-phosphate 5-kinase and not ROCK kinases

31 March 2020

1 reference

Association of the myosin-binding subunit of myosin phosphatase and moesin: dual regulation of moesin phosphorylation by Rho-associated kinase and myosin phosphatase

31 March 2020

1 reference

RhoA-dependent phosphorylation and relocalization of ERM proteins into apical membrane/actin protrusions in fibroblasts

31 March 2020

1 reference

Rho regulates association of both the ERM family and vinculin with the plasma membrane in MDCK cells

31 March 2020

1 reference

Rho- and rac-dependent assembly of focal adhesion complexes and actin filaments in permeabilized fibroblasts: an essential role for ezrin/radixin/moesin proteins

31 March 2020

1 reference

The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho

31 March 2020

1 reference

Structural basis for neurofibromatosis type 2. Crystal structure of the merlin FERM domain

31 March 2020

1 reference

The structure of the FERM domain of merlin, the neurofibromatosis type 2 gene product

31 March 2020

1 reference

Distinct cellular and subcellular patterns of expression imply distinct functions for the Drosophila homologues of moesin and the neurofibromatosis 2 tumor suppressor, merlin

31 March 2020

1 reference

Merlin differentially associates with the microtubule and actin cytoskeleton

31 March 2020

1 reference

Ezrin, radixin, and moesin are components of Schwann cell microvilli

31 March 2020

1 reference

Structural analysis of Drosophila merlin reveals functional domains important for growth control and subcellular localization

31 March 2020

1 reference

Functional analysis of the neurofibromatosis type 2 protein by means of disease-causing point mutations

31 March 2020

1 reference

Interaction between two isoforms of the NF2 tumor suppressor protein, merlin, and between merlin and ezrin, suggests modulation of ERM proteins by merlin.

31 March 2020

1 reference

Interdomain interaction of merlin isoforms and its influence on intermolecular binding to NHE-RF

31 March 2020

1 reference

Interdomain binding mediates tumor growth suppression by the NF2 gene product

31 March 2020

1 reference

Hierarchy of merlin and ezrin N- and C-terminal domain interactions in homo- and heterotypic associations and their relationship to binding of scaffolding proteins EBP50 and E3KARP.

31 March 2020

1 reference

The NF2 interactor, hepatocyte growth factor-regulated tyrosine kinase substrate (HRS), associates with merlin in the "open" conformation and suppresses cell growth and motility

31 March 2020

1 reference

Expression level, subcellular distribution and rho-GDI binding affinity of merlin in comparison with Ezrin/Radixin/Moesin proteins

31 March 2020

1 reference

Neurofibromatosis 2 tumour suppressor schwannomin interacts with betaII-spectrin

31 March 2020

1 reference

Merlin phosphorylation by p21-activated kinase 2 and effects of phosphorylation on merlin localization

31 March 2020

1 reference

Regulation of the neurofibromatosis type 2 tumor suppressor protein, merlin, by adhesion and growth arrest stimuli

31 March 2020

1 reference

The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling.

31 March 2020

1 reference

The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44

31 March 2020

1 reference

The FERM domain: a unique module involved in the linkage of cytoplasmic proteins to the membrane

31 March 2020

1 reference

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

31 March 2020

1 reference

Janus kinases and focal adhesion kinases play in the 4.1 band: a superfamily of band 4.1 domains important for cell structure and signal transduction

31 March 2020

1 reference

Comparative analysis of the Band 4.1/ezrin-related protein tyrosine phosphatase Pez from two Drosophila species: implications for structure and function.

31 March 2020

1 reference

Structural and evolutionary relationships among protein tyrosine phosphatase domains

31 March 2020

1 reference

Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors

31 March 2020

1 reference

Schwann cell hyperplasia and tumors in transgenic mice expressing a naturally occurring mutant NF2 protein

31 March 2020

1 reference

Nf2 gene inactivation in arachnoidal cells is rate-limiting for meningioma development in the mouse

31 March 2020

1 reference

Moesin interacts with the cytoplasmic region of intercellular adhesion molecule-3 and is redistributed to the uropod of T lymphocytes during cell polarization

31 March 2020

1 reference

Identification of EBP50: A PDZ-containing phosphoprotein that associates with members of the ezrin-radixin-moesin family

31 March 2020

1 reference

Interaction of radixin with Rho small G protein GDP/GTP exchange protein Dbl

31 March 2020

1 reference

Ezrin interacts with focal adhesion kinase and induces its activation independently of cell-matrix adhesion

31 March 2020

1 reference

Ezrin, a plasma membrane-microfilament linker, signals cell survival through the phosphatidylinositol 3-kinase/Akt pathway

31 March 2020

1 reference

CD95 (APO-1/Fas) linkage to the actin cytoskeleton through ezrin in human T lymphocytes: a novel regulatory mechanism of the CD95 apoptotic pathway

31 March 2020

1 reference

Characterization of human palladin, a microfilament-associated protein

31 March 2020

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12154370

31 March 2020

Identifiers

3 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017

957715

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12154370%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

11 November 2019

1013550011

0 references

957715

1 reference

Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12154370

3 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017

957715

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12154370%20AND%20SRC:MED&resulttype=core&format=json