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Alpha Catenin Dmel_CG17947
Protein found in Drosophila melanogaster
CG17947-PA
CG17947-PB
alpha catenin
Dalpha-Catenin
alpha-Cat-PA
CG17947 gene product from transcript CG17947-RA
D-alpha-catenin
alpha-Cat-PB
a-catenin
dalphacatenin
alphaCatenin
alpha-Cat
Dalpha-cadherin
alpha-Catenin
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P35220
part of
Alpha-catenin/vinculin-like superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P35220
Alpha-catenin
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P35220
Vinculin, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P35220
encoded by
alpha-Cat
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P35220
molecular function
actin binding
determination method
ISS
1 reference
retrieved
8 April 2019
stated in
Flying through the drosophila cytoskeletal genome.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
ISS
structural molecule activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
IEA
protein binding
determination method
IPI
3 references
retrieved
8 April 2019
stated in
Roles of Armadillo, a Drosophila catenin, during central nervous system development.
GOA
curator
UniProt
UniProt protein ID
P35220
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
IPI
retrieved
8 April 2019
stated in
BCL9-2 binds Arm/beta-catenin in a Tyr142-independent manner and requires Pygopus for its function in Wg/Wnt signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
IPI
retrieved
8 April 2019
stated in
Monomeric α-catenin links cadherin to the actin cytoskeleton
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
IPI
cytoskeletal protein binding
determination method
ISS
1 reference
retrieved
8 April 2019
stated in
Flying through the drosophila cytoskeletal genome.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
ISS
identical protein binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
Monomeric α-catenin links cadherin to the actin cytoskeleton
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
IPI
cadherin binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
IEA
actin filament binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
IEA
cell component
cytoplasm
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P35220
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
IEA
cytoskeleton
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P35220
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
IEA
plasma membrane
determination method
HDA
IDA
IEA
6 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P35220
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
IEA
retrieved
8 April 2019
stated in
The Drosophila p21-activated kinase Mbt modulates DE-cadherin-mediated cell adhesion by phosphorylation of Armadillo
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
IDA
retrieved
8 April 2019
stated in
α-Catenin stabilises Cadherin-Catenin complexes and modulates actomyosin dynamics to allow pulsatile apical contraction.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
IDA
retrieved
8 April 2019
stated in
The Arf-GEF Schizo/Loner regulates N-cadherin to induce fusion competence of Drosophila myoblasts
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
IDA
retrieved
8 April 2019
stated in
Mapping organelle proteins and protein complexes in Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
HDA
retrieved
8 April 2019
stated in
Subcellular localisations of the CPTI collection of YFP-tagged proteins in Drosophila embryos.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
HDA
adherens junction
determination method
IDA
IEA
NAS
4 references
retrieved
8 April 2019
stated in
Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
NAS
retrieved
8 April 2019
stated in
Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
NAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P35220
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
IEA
retrieved
8 April 2019
stated in
Analysis of the expression patterns, subcellular localisations and interaction partners of Drosophila proteins using a pigP protein trap library
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
IDA
spot adherens junction
determination method
NAS
1 reference
retrieved
8 April 2019
stated in
The polarising role of cell adhesion molecules in early development
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
NAS
zonula adherens
determination method
NAS
1 reference
retrieved
8 April 2019
stated in
Epithelial polarity in flies: more than just crumbs.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
NAS
actin cytoskeleton
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
IEA
membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P35220
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
IEA
catenin complex
determination method
IDA
ISS
2 references
retrieved
8 April 2019
stated in
The evolution of cell adhesion
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
ISS
retrieved
8 April 2019
stated in
The Drosophila p21-activated kinase Mbt modulates DE-cadherin-mediated cell adhesion by phosphorylation of Armadillo
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
IDA
cell junction
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P35220
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
IEA
biological process
apical constriction
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
α-Catenin stabilises Cadherin-Catenin complexes and modulates actomyosin dynamics to allow pulsatile apical contraction.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
IMP
cell adhesion
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P35220
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
IEA
establishment or maintenance of cell polarity
determination method
NAS
1 reference
retrieved
8 April 2019
stated in
Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
NAS
adherens junction organization
determination method
IMP
2 references
retrieved
8 April 2019
stated in
Mutational analysis supports a core role for Drosophila α-catenin in adherens junction function.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
IMP
retrieved
8 April 2019
stated in
Monomeric α-catenin links cadherin to the actin cytoskeleton
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
IMP
adherens junction assembly
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
α-Catenin stabilises Cadherin-Catenin complexes and modulates actomyosin dynamics to allow pulsatile apical contraction.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
IMP
dorsal closure, amnioserosa morphology change
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
α-Catenin stabilises Cadherin-Catenin complexes and modulates actomyosin dynamics to allow pulsatile apical contraction.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
IMP
head morphogenesis
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Mutational analysis supports a core role for Drosophila α-catenin in adherens junction function.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35220
determination method
IMP
has part(s)
Vinculin, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P35220
Identifiers
RefSeq protein ID
NP_001287154
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
40517
NP_524219
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
40517
UniProt protein ID
P35220
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P35220
Ensembl protein ID
FBpp0308926
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0308926
FBpp0070037
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0070037
Sitelinks
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Wikinews
(0 entries)
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Wikiquote
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Wikisource
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Wikiversity
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Wikivoyage
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Wiktionary
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Multilingual sites
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