(Q29810114)

English

Cyp6g1 Dmel_CG8453

Protein found in Drosophila melanogaster

CG8453-PA
CG8453 gene product from transcript CG8453-RB
CYP6-like
resistance to DDT
CG8453-PB
resistance to insecticide on chromosome 2
Cyp6g1
cytochrome P450
resistance to Insecticide-DDT
Cyp6g1-PB
Cyp6g1-PA

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Statements

1 reference

25 May 2022

cytochrome P450 superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9V674

cytochrome P450, E-class, group I

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9V674

cytochrome P450, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

monooxygenase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V674

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V674

determination method

IEA

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V674

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V674

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V674

determination method

IEA

oxidoreductase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V674

determination method

IEA

cell component

endoplasmic reticulum

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V674

determination method

IEA

endoplasmic reticulum membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V674

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V674

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V674

determination method

IEA

intracellular membrane-bounded organelle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V674

determination method

IEA

biological process

response to insecticide

5 references

8 April 2019

DDT resistance in Drosophila correlates with Cyp6g1 over-expression and confers cross-resistance to the neonicotinoid imidacloprid

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V674

8 April 2019

A single p450 allele associated with insecticide resistance in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V674

8 April 2019

Evolutionary changes in gene expression, coding sequence and copy-number at the Cyp6g1 locus contribute to resistance to multiple insecticides in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V674

8 April 2019

Evaluating the insecticide resistance potential of eight Drosophila melanogaster cytochrome P450 genes by transgenic over-expression.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V674

8 April 2019

Microarray analysis of cytochrome P450 mediated insecticide resistance in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V674

4 references

31 January 2018

Copy number variation and transposable elements feature in recent, ongoing adaptation at the Cyp6g1 locus

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V674&geneProductId=UniProtKB:Q9V674

31 January 2018

Evaluating the insecticide resistance potential of eight Drosophila melanogaster cytochrome P450 genes by transgenic over-expression.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V674&geneProductId=UniProtKB:Q9V674

31 January 2018

A single p450 allele associated with insecticide resistance in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V674&geneProductId=UniProtKB:Q9V674

31 January 2018

Microarray analysis of cytochrome P450 mediated insecticide resistance in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V674&geneProductId=UniProtKB:Q9V674

determination method

IMP

response to organophosphorus

1 reference

8 April 2019

Microarray analysis of cytochrome P450 mediated insecticide resistance in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V674

determination method

IMP

response to mercury ion

1 reference

8 April 2019

Drosophila CYP6g1 and its human homolog CYP3A4 confer tolerance to methylmercury during development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V674

determination method

IMP

insecticide catabolic process

2 references

31 January 2018

Metabolism of methoxychlor by the P450-monooxygenase CYP6G1 involved in insecticide resistance of Drosophila melanogaster after expression in cell cultures of Nicotiana tabacum

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V674&geneProductId=UniProtKB:Q9V674

31 January 2018

Metabolism of imidacloprid and DDT by P450 CYP6G1 expressed in cell cultures of Nicotiana tabacum suggests detoxification of these insecticides in Cyp6g1-overexpressing strains of Drosophila melanogaster, leading to resistance.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V674&geneProductId=UniProtKB:Q9V674

5 references

8 April 2019

Copy number variation and transposable elements feature in recent, ongoing adaptation at the Cyp6g1 locus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V674

8 April 2019

Evaluating the insecticide resistance potential of eight Drosophila melanogaster cytochrome P450 genes by transgenic over-expression.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V674

8 April 2019

Microarray analysis of cytochrome P450 mediated insecticide resistance in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V674

8 April 2019

A single p450 allele associated with insecticide resistance in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V674

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V674

determination method

IBA

insecticide catabolic process

3 references

8 April 2019

Metabolism of methoxychlor by the P450-monooxygenase CYP6G1 involved in insecticide resistance of Drosophila melanogaster after expression in cell cultures of Nicotiana tabacum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V674

8 April 2019

Metabolism of imidacloprid and DDT by P450 CYP6G1 expressed in cell cultures of Nicotiana tabacum suggests detoxification of these insecticides in Cyp6g1-overexpressing strains of Drosophila melanogaster, leading to resistance.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V674

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V674

determination method

IBA

has part(s)

cytochrome P450, conserved site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9V674

Identifiers

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

1 reference

(Q29810114)

Cyp6g1 Dmel_CG8453

Statements

Identifiers

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