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(Q29810212)
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English
Bag of marbles Dmel_CG10422
Protein found in Drosophila melanogaster
CG10422 gene product from transcript CG10422-RA
transcript alpha
bag of marble
CG10422-PA
bag-of-marbles
bam
bam-PA
bag of marbles
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P22745
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P22745
encoded by
bam
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P22745
molecular function
translation repressor activity, mRNA regulatory element binding
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
eIF4A controls germline stem cell self-renewal by directly inhibiting BAM function in the Drosophila ovary
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IDA
mRNA 3'-UTR binding
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
A self-limiting switch based on translational control regulates the transition from proliferation to differentiation in an adult stem cell lineage
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IDA
protein binding
determination method
IPI
3 references
retrieved
8 April 2019
stated in
Bam and Bgcn antagonize Nanos-dependent germ-line stem cell maintenance
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IPI
retrieved
8 April 2019
stated in
eIF4A controls germline stem cell self-renewal by directly inhibiting BAM function in the Drosophila ovary
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IPI
retrieved
8 April 2019
stated in
Protein competition switches the function of COP9 from self-renewal to differentiation.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IPI
cell component
cytoplasm
determination method
IDA
TAS
3 references
retrieved
8 April 2019
stated in
Genetic control of cell proliferation and differentiation in Drosophila spermatogenesis.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
TAS
retrieved
8 April 2019
stated in
Three RNA binding proteins form a complex to promote differentiation of germline stem cell lineage in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IDA
retrieved
8 April 2019
stated in
A role for the Drosophila bag-of-marbles protein in the differentiation of cystoblasts from germline stem cells.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IDA
fusome
determination method
IDA
TAS
2 references
retrieved
8 April 2019
stated in
Genetic control of cell proliferation and differentiation in Drosophila spermatogenesis.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
TAS
retrieved
8 April 2019
stated in
A role for the Drosophila bag-of-marbles protein in the differentiation of cystoblasts from germline stem cells.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IDA
spectrosome
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
A role for the Drosophila bag-of-marbles protein in the differentiation of cystoblasts from germline stem cells.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IDA
biological process
cell fate specification
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Genetic control of cell proliferation and differentiation in Drosophila spermatogenesis.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
TAS
cell cycle
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P22745
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IEA
male meiotic nuclear division
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Genetic control of cell proliferation and differentiation in Drosophila spermatogenesis.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
TAS
multicellular organism development
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P22745
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IEA
gamete generation
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
bag-of-marbles: a Drosophila gene required to initiate both male and female gametogenesis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IMP
germ cell development
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Genetic control of cell proliferation and differentiation in Drosophila spermatogenesis.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
TAS
cystoblast division
determination method
IMP
TAS
2 references
retrieved
8 April 2019
stated in
Germ cell development in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
TAS
retrieved
8 April 2019
stated in
A role for the Drosophila bag-of-marbles protein in the differentiation of cystoblasts from germline stem cells.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IMP
spermatogenesis
determination method
IEA
IMP
TAS
4 references
retrieved
8 April 2019
stated in
Genetic control of cell proliferation and differentiation in Drosophila spermatogenesis.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
TAS
retrieved
8 April 2019
stated in
A role for the Drosophila bag-of-marbles protein in the differentiation of cystoblasts from germline stem cells.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
TAS
retrieved
8 April 2019
stated in
Control of a Novel Spermatocyte-Promoting Factor by the Male Germline Sex Determination Factor PHF7 of Drosophila melanogaster.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IMP
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P22745
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IEA
spermatogonial cell division
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Accumulation of a differentiation regulator specifies transit amplifying division number in an adult stem cell lineage
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IMP
negative regulation of translation
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Three RNA binding proteins form a complex to promote differentiation of germline stem cell lineage in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IMP
cell differentiation
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P22745
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IEA
germ-line stem cell population maintenance
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Bam and Bgcn antagonize Nanos-dependent germ-line stem cell maintenance
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IDA
germarium-derived female germ-line cyst formation
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Pelota controls self-renewal of germline stem cells by repressing a Bam-independent differentiation pathway.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IMP
cell competition in a multicellular organism
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Differentiation-defective stem cells outcompete normal stem cells for niche occupancy in the Drosophila ovary.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IMP
germ-line stem cell division
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
The expression profile of purified Drosophila germline stem cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IMP
fusome organization
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
A role for the Drosophila bag-of-marbles protein in the differentiation of cystoblasts from germline stem cells.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IMP
female germ-line stem cell asymmetric division
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
eIF4A controls germline stem cell self-renewal by directly inhibiting BAM function in the Drosophila ovary
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IMP
female germ-line cyst formation
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Germline cysts: a conserved phase of germ cell development?
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
TAS
oogenesis
determination method
IEA
IMP
3 references
retrieved
8 April 2019
stated in
eIF4A controls germline stem cell self-renewal by directly inhibiting BAM function in the Drosophila ovary
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IMP
retrieved
8 April 2019
stated in
A role for the Drosophila bag-of-marbles protein in the differentiation of cystoblasts from germline stem cells.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IMP
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P22745
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IEA
male germline stem cell symmetric division
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Differentiation-defective stem cells outcompete normal stem cells for niche occupancy in the Drosophila ovary.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22745
determination method
IMP
Identifiers
RefSeq protein ID
NP_476800
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
43038
UniProt protein ID
P22745
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P22745
Ensembl protein ID
FBpp0084243
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0084243
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