(Q29810410)

English

Notch Dmel_CG3936

Protein found in Drosophila melanogaster

chopped
facet
N
strawberry
CG3936 gene product from transcript CG3936-RA
split
abruptex
notch
CG3936-PB
NICD
confluens
N-PB
notchoid
CG3936-PA
N-PA
dNotch

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07207

Notch-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07207

Growth factor receptor cysteine-rich domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07207

Ankyrin repeat-containing domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07207

Notch, NODP domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

based on heuristic

inferred from protein domain or family

Notch, NOD domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Domain of unknown function DUF3454, notch, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ankyrin repeat-containing domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like calcium-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like calcium-binding, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ankyrin repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

Drosophila melanogaster

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

chromatin binding

determination method

1 reference

8 April 2019

An NRSF/REST-like repressor downstream of Ebi/SMRTER/Su(H) regulates eye development in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

calcium ion binding

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

protein binding

determination method

24 references

8 April 2019

AKAP200 promotes Notch stability by protecting it from Cbl/lysosome-mediated degradation in Drosophila melanogaster.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Drosophila Nedd4 regulates endocytosis of notch and suppresses its ligand-independent activation.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Involvement of a proline-rich motif and RING-H2 finger of Deltex in the regulation of Notch signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Regulation of notch endosomal sorting and signaling by Drosophila Nedd4 family proteins.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Insensitive is a corepressor for Suppressor of Hairless and regulates Notch signalling during neural development

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Compensatory flux changes within an endocytic trafficking network maintain thermal robustness of Notch signaling

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

The suppressor of hairless protein participates in notch receptor signaling.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Structure and Notch receptor binding of the tandem WWE domain of Deltex

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H)

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

The PDZ protein Canoe/AF-6 links Ras-MAPK, Notch and Wingless/Wnt signaling pathways by directly interacting with Ras, Notch and Dishevelled

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Conformational variability of the intracellular domain of Drosophila Notch and its interaction with Suppressor of Hairless

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Glycosyltransferase activity of Fringe modulates Notch-Delta interactions.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Numb inhibits membrane localization of Sanpodo, a four-pass transmembrane protein, to promote asymmetric divisions in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Sanpodo controls sensory organ precursor fate by directing Notch trafficking and binding γ-secretase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Uninflatable and Notch control the targeting of Sara endosomes during asymmetric division.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Gene deletion screen for cardiomyopathy in adult Drosophila identifies a new notch ligand.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Involvement of a proline-rich motif and RING-H2 finger of Deltex in the regulation of Notch signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Specificity and Autoregulation of Notch Binding by Tandem WW Domains in Suppressor of Deltex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Polarized exocytosis and transcytosis of Notch during its apical localization in Drosophila epithelial cells.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Conformational variability of the intracellular domain of Drosophila Notch and its interaction with Suppressor of Hairless

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Drosophila Nedd4 regulates endocytosis of notch and suppresses its ligand-independent activation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

The adhesion force of Notch with Delta and the rate of Notch signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Cytosolic interaction between deltex and Notch ankyrin repeats implicates deltex in the Notch signaling pathway.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

transmembrane signaling receptor activity

determination method

1 reference

8 April 2019

The adhesion force of Notch with Delta and the rate of Notch signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

intracellular anatomical structure

determination method

1 reference

10 September 2018

The suppressor of hairless protein participates in notch receptor signaling.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

determination method

5 references

1 January 2018

The polarisation of the anteroposterior axis in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

1 January 2018

Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

1 January 2018

Signal-induced transcriptional activation by Dif requires the dTRAP80 mediator module

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

1 January 2018

Dynamic intracellular distribution of Notch during activation and asymmetric cell division revealed by functional fluorescent fusion proteins.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

determination method

1 reference

8 April 2019

Dynamic intracellular distribution of Notch during activation and asymmetric cell division revealed by functional fluorescent fusion proteins.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

determination method

1 reference

8 April 2019

Dynamic intracellular distribution of Notch during activation and asymmetric cell division revealed by functional fluorescent fusion proteins.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

endoplasmic reticulum lumen

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

plasma membrane

determination method

adherens junction

determination method

1 reference

8 April 2019

Polarized exocytosis and transcytosis of Notch during its apical localization in Drosophila epithelial cells.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

integral component of membrane

determination method

endocytic vesicle

determination method

1 reference

8 April 2019

Ligand-independent traffic of Notch buffers activated Armadillo in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

cytoplasmic vesicle

determination method

1 reference

8 April 2019

Sec15, a component of the exocyst, promotes notch signaling during the asymmetric division of Drosophila sensory organ precursors.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

protein-containing complex

determination method

1 reference

8 April 2019

Conformational variability of the intracellular domain of Drosophila Notch and its interaction with Suppressor of Hairless

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

subapical complex

determination method

1 reference

8 April 2019

Polarized exocytosis and transcytosis of Notch during its apical localization in Drosophila epithelial cells.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

determination method

4 references

8 April 2019

Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Dynamic intracellular distribution of Notch during activation and asymmetric cell division revealed by functional fluorescent fusion proteins.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Signal-induced transcriptional activation by Dif requires the dTRAP80 mediator module

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

integral component of membrane

determination method

4 references

14 January 2019

Cell fate specification in the Drosophila retina

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

14 January 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

14 January 2019

The adhesion force of Notch with Delta and the rate of Notch signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

CSL-Notch-Mastermind transcription factor complex

determination method

1 reference

14 January 2019

Structural and functional analysis of the repressor complex in the Notch signaling pathway of Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

determination method

1 reference

8 April 2019

Echinoid facilitates Notch pathway signalling during Drosophila neurogenesis through functional interaction with Delta.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

integral component of plasma membrane

determination method

1 reference

8 April 2019

A fluorescent tagging approach in Drosophila reveals late endosomal trafficking of Notch and Sanpodo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

zonula adherens

determination method

1 reference

8 April 2019

Echinoid synergizes with the Notch signaling pathway in Drosophila mesothorax bristle patterning.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

integral component of membrane

determination method

CSL-Notch-Mastermind transcription factor complex

determination method

3 references

8 April 2019

Structural and functional analysis of the repressor complex in the Notch signaling pathway of Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Activation of the Notch Signaling Pathway In Vivo Elicits Changes in CSL Nuclear Dynamics.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

A human protein with sequence similarity to Drosophila mastermind coordinates the nuclear form of notch and a CSL protein to build a transcriptional activator complex on target promoters

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

biological process

negative regulation of transcription by RNA polymerase II

determination method

1 reference

14 January 2019

Cell fate specification in the Drosophila retina

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

establishment of imaginal disc-derived wing hair orientation

determination method

1 reference

8 April 2019

Planar polarity: location, location, location

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

compound eye morphogenesis

determination method

3 references

8 April 2019

Cellular behavior in the developing Drosophila pupal retina

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Notch signaling controls proliferation through cell-autonomous and non-autonomous mechanisms in the Drosophila eye.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Growth and specification of the eye are controlled independently by Eyegone and Eyeless in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

positive regulation of neuroblast proliferation

determination method

4 references

8 April 2019

bHLH-O proteins are crucial for Drosophila neuroblast self-renewal and mediate Notch-induced overproliferation.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

The bHLH repressor Deadpan regulates the self-renewal and specification of Drosophila larval neural stem cells independently of Notch

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Aurora-A acts as a tumor suppressor and regulates self-renewal of Drosophila neuroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

The bantam microRNA acts through Numb to exert cell growth control and feedback regulation of Notch in tumor-forming stem cells in the Drosophila brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

defense response to insect

determination method

1 reference

8 April 2019

An unexpected link between notch signaling and ROS in restricting the differentiation of hematopoietic progenitors in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

regulation of glycolytic process

determination method

1 reference

8 April 2019

Notch stimulates growth by direct regulation of genes involved in the control of glycolysis and the tricarboxylic acid cycle.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

transcription, DNA-templated

determination method

1 reference

21 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

regulation of transcription, DNA-templated

determination method

1 reference

21 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

actin filament organization

determination method

1 reference

8 April 2019

Influence of Notch on dorsoventral compartmentalization and actin organization in the Drosophila wing.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

determination method

1 reference

14 January 2019

Cell fate specification in the Drosophila retina

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

ovarian follicle cell migration

determination method

1 reference

8 April 2019

Bunched sets a boundary for Notch signaling to pattern anterior eggshell structures during Drosophila oogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

oocyte anterior/posterior axis specification

determination method

1 reference

8 April 2019

Drosophila oogenesis: coordinating germ line and soma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

regulation of mitotic cell cycle

determination method

1 reference

8 April 2019

Regulation of Cell Cycles in Drosophila Development: Intrinsic and Extrinsic Cues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

determination method

1 reference

8 April 2019

Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

ectoderm development

determination method

1 reference

8 April 2019

A role for the Drosophila neurogenic genes in mesoderm differentiation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

nervous system development

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

glial cell fate determination

determination method

3 references

8 April 2019

Notch signaling represses the glial fate in fly PNS.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

A requirement for Notch in the genesis of a subset of glial cells in the Drosophila embryonic central nervous system which arise through asymmetric divisions.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Context-dependent utilization of Notch activity in Drosophila glial determination.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

neuroblast proliferation

determination method

1 reference

8 April 2019

The tumor suppressors Brat and Numb regulate transit-amplifying neuroblast lineages in Drosophila

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

determination method

1 reference

8 April 2019

Notch steers Drosophila ISNb motor axons by regulating the Abl signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

ventral cord development

determination method

1 reference

8 April 2019

Genetic control of Drosophila nerve cord development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

sensory organ development

determination method

1 reference

8 April 2019

Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

open tracheal system development

determination method

1 reference

21 June 2018

Cell fate choices in Drosophila tracheal morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

foregut morphogenesis

determination method

1 reference

8 April 2019

Cooperation of JAK/STAT and Notch signaling in the Drosophila foregut.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

imaginal disc growth

determination method

1 reference

8 April 2019

The genetic control of organ growth: insights from Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

imaginal disc pattern formation

determination method

1 reference

8 April 2019

The genetic control of organ growth: insights from Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

dorsal/ventral pattern formation, imaginal disc

determination method

1 reference

8 April 2019

Selector and signalling molecules cooperate in organ patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

dorsal/ventral lineage restriction, imaginal disc

determination method

1 reference

8 April 2019

Sticking together and sorting things out: adhesion as a force in development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

eye-antennal disc morphogenesis

determination method

1 reference

8 April 2019

Notch-dependent epithelial fold determines boundary formation between developmental fields in the Drosophila antenna.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

R8 cell fate commitment

determination method

1 reference

14 January 2019

Cell fate specification in the Drosophila retina

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

R3/R4 cell fate commitment

determination method

1 reference

8 April 2019

Planar cell polarization: do the same mechanisms regulate Drosophila tissue polarity and vertebrate gastrulation?

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

wing disc proximal/distal pattern formation

determination method

1 reference

8 April 2019

Pattern formation in the Drosophila wing: The development of the veins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

imaginal disc-derived wing vein specification

determination method

1 reference

8 April 2019

Regulation of Notch signaling by Drosophila heparan sulfate 3-O sulfotransferase.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

imaginal disc-derived wing morphogenesis

determination method

3 references

8 April 2019

Selector and signalling molecules cooperate in organ patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Phospholipid membrane composition affects EGF receptor and Notch signaling through effects on endocytosis during Drosophila development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Vein-positioning in the Drosophila wing in response to Hh; new roles of Notch signaling.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

leg disc morphogenesis

determination method

1 reference

8 April 2019

Subdividing cell populations in the developing limbs of Drosophila: do wing veins and leg segments define units of growth control?

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

mesoderm development

determination method

1 reference

8 April 2019

A role for the Drosophila neurogenic genes in mesoderm differentiation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

skeletal muscle tissue development

determination method

1 reference

8 April 2019

Drosophila SNS, a member of the immunoglobulin superfamily that is essential for myoblast fusion.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

muscle cell fate determination

determination method

1 reference

8 April 2019

Myogenic cells fates are antagonized by Notch only in asymmetric lineages of the Drosophila heart, with or without cell division.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

anesthesia-resistant memory

determination method

1 reference

8 April 2019

Notch signaling in Drosophila long-term memory formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

long-term memory

determination method

3 references

8 April 2019

Notch signaling in Drosophila long-term memory formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Notch-inducible hyperphosphorylated CREB and its ultradian oscillation in long-term memory formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

The Drosophila cell adhesion molecule klingon is required for long-term memory formation and is regulated by Notch.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

motor neuron axon guidance

determination method

1 reference

8 April 2019

Noncanonical Notch function in motor axon guidance is mediated by Rac GTPase and the GEF1 domain of Trio

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

positive regulation of cell population proliferation

determination method

1 reference

8 April 2019

Notch signaling controls proliferation through cell-autonomous and non-autonomous mechanisms in the Drosophila eye.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

determination of adult lifespan

determination method

1 reference

8 April 2019

Requirement of Notch in adulthood for neurological function and longevity.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

glial cell migration

determination method

1 reference

8 April 2019

Notch and Numb are required for normal migration of peripheral glia in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

chaeta morphogenesis

determination method

1 reference

8 April 2019

Evidence that nervy, the Drosophila homolog of ETO/MTG8, promotes mechanosensory organ development by enhancing Notch signaling.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

imaginal disc-derived wing margin morphogenesis

determination method

5 references

8 April 2019

Regulation of Notch signaling by a novel mechanism involving suppressor of hairless stability and carboxyl terminus-truncated notch

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Specific EGF repeats of Notch mediate interactions with Delta and serrate: Implications for notch as a multifunctional receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Notch down-regulation by endocytosis is essential for pigment cell determination and survival in the Drosophila retina

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Regulation of Notch signaling by Drosophila heparan sulfate 3-O sulfotransferase.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

response to symbiont

determination method

1 reference

8 April 2019

Notch signaling controls lineage specification during Drosophila larval hematopoiesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

dorsal/ventral axis specification

determination method

1 reference

8 April 2019

Notch and PKC are involved in formation of the lateral region of the dorso-ventral axis in Drosophila embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

anterior/posterior pattern specification

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

glial cell differentiation

determination method

1 reference

8 April 2019

Notch and Numb are required for normal migration of peripheral glia in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

positive regulation of gene expression

determination method

neuroblast development

determination method

3 references

8 April 2019

The tumor suppressors Brat and Numb regulate transit-amplifying neuroblast lineages in Drosophila

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

The bHLH repressor Deadpan regulates the self-renewal and specification of Drosophila larval neural stem cells independently of Notch

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Lineage-specific cell death in postembryonic brain development of Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

morphogenesis of follicular epithelium

determination method

1 reference

8 April 2019

Drosophila oogenesis: coordinating germ line and soma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

sensory organ precursor cell fate determination

determination method

1 reference

8 April 2019

Uninflatable and Notch control the targeting of Sara endosomes during asymmetric division.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

chaeta development

determination method

1 reference

8 April 2019

On the mechanism underlying the divergent retinal and bristle defects of M8* (E(spl)D) in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

cell differentiation

determination method

ovarian follicle cell development

determination method

4 references

8 April 2019

Control of mRNA stability and translation during Drosophila development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Quantitative microscopy of the Drosophila ovary shows multiple niche signals specify progenitor cell fate.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

A large-scale in vivo RNAi screen to identify genes involved in Notch-mediated follicle cell differentiation and cell cycle switches

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Bunched sets a boundary for Notch signaling to pattern anterior eggshell structures during Drosophila oogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

germarium-derived female germ-line cyst encapsulation

determination method

1 reference

8 April 2019

Drosophila oogenesis: coordinating germ line and soma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

ovarian follicle cell stalk formation

determination method

3 references

8 April 2019

Integration of epithelial patterning and morphogenesis in Drosophila ovarian follicle cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

A Notch/Delta-dependent relay mechanism establishes anterior-posterior polarity in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

The neurogenic genes egghead and brainiac define a novel signaling pathway essential for epithelial morphogenesis during Drosophila oogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

germ-line stem cell population maintenance

determination method

1 reference

8 April 2019

Notch signaling controls germline stem cell niche formation in the Drosophila ovary.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

oocyte localization involved in germarium-derived egg chamber formation

determination method

1 reference

8 April 2019

A Notch/Delta-dependent relay mechanism establishes anterior-posterior polarity in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

epithelial cell type specification, open tracheal system

determination method

1 reference

8 April 2019

Social interactions among epithelial cells during tracheal branching morphogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

negative regulation of terminal cell fate specification, open tracheal system

determination method

1 reference

21 June 2018

Cell fate choices in Drosophila tracheal morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

negative regulation of fusion cell fate specification

determination method

1 reference

21 June 2018

Cell fate choices in Drosophila tracheal morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

embryonic hemopoiesis

determination method

1 reference

8 April 2019

A Serrate-expressing signaling center controls Drosophila hematopoiesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

embryonic crystal cell differentiation

determination method

1 reference

8 April 2019

Thicker than blood: conserved mechanisms in Drosophila and vertebrate hematopoiesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

larval lymph gland hemopoiesis

determination method

1 reference

8 April 2019

A Serrate-expressing signaling center controls Drosophila hematopoiesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

lymph gland crystal cell differentiation

determination method

1 reference

10 September 2018

Blood cells of Drosophila: cell lineages and role in host defence

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

lamellocyte differentiation

determination method

1 reference

8 April 2019

Notch signaling controls lineage specification during Drosophila larval hematopoiesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

hemocyte proliferation

determination method

1 reference

8 April 2019

A Serrate-expressing signaling center controls Drosophila hematopoiesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

negative regulation of lamellocyte differentiation

determination method

1 reference

8 April 2019

An unexpected link between notch signaling and ROS in restricting the differentiation of hematopoietic progenitors in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

eye-antennal disc development

determination method

1 reference

8 April 2019

Temporal switching of regulation and function of eye gone (eyg) in Drosophila eye development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

wing disc pattern formation

determination method

1 reference

8 April 2019

In vivo analysis of the Notch receptor S1 cleavage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

imaginal disc-derived leg segmentation

determination method

1 reference

8 April 2019

Notch-mediated segmentation and growth control of the Drosophila leg.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

female germ-line stem cell population maintenance

determination method

1 reference

8 April 2019

Notch signaling mediates the age-associated decrease in adhesion of germline stem cells to the niche

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

compound eye cone cell fate commitment

determination method

1 reference

8 April 2019

Developmental signaling: shrimp and strawberries help flies make cones

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

regulation of cardioblast cell fate specification

determination method

1 reference

8 April 2019

Myogenic cells fates are antagonized by Notch only in asymmetric lineages of the Drosophila heart, with or without cell division.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

regulation of crystal cell differentiation

determination method

1 reference

8 April 2019

Transcriptional regulation of hematopoiesis in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

positive regulation of crystal cell differentiation

determination method

1 reference

8 April 2019

An unexpected link between notch signaling and ROS in restricting the differentiation of hematopoietic progenitors in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

positive regulation of neuron apoptotic process

determination method

1 reference

8 April 2019

Lineage-specific cell death in postembryonic brain development of Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

cell dedifferentiation

determination method

1 reference

8 April 2019

dFezf/Earmuff maintains the restricted developmental potential of intermediate neural progenitors in Drosophila.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

negative regulation of compound eye photoreceptor development

determination method

1 reference

8 April 2019

Notch signaling controls proliferation through cell-autonomous and non-autonomous mechanisms in the Drosophila eye.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

R8 cell development

determination method

1 reference

14 January 2019

Cell fate specification in the Drosophila retina

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

R8 cell differentiation

determination method

1 reference

1 January 2018

R8 development in the Drosophila eye: a paradigm for neural selection and differentiation.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

regulation of R8 cell spacing in compound eye

determination method

1 reference

1 January 2018

R8 development in the Drosophila eye: a paradigm for neural selection and differentiation.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

regulation of cell differentiation

determination method

1 reference

8 April 2019

A transient niche regulates the specification of Drosophila intestinal stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

positive regulation of Notch signaling pathway

determination method

1 reference

1 January 2018

The adhesion force of Notch with Delta and the rate of Notch signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

positive regulation of transcription, DNA-templated

determination method

1 reference

8 April 2019

Notch stimulates growth by direct regulation of genes involved in the control of glycolysis and the tricarboxylic acid cycle.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

positive regulation of transcription by RNA polymerase II

determination method

negative regulation of JNK cascade

determination method

1 reference

8 April 2019

Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

retinal cell programmed cell death

determination method

1 reference

8 April 2019

Patterning the fly eye: the role of apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

compound eye retinal cell programmed cell death

determination method

1 reference

8 April 2019

Cell proliferation, survival, and death in the Drosophila eye.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

dorsal appendage formation

determination method

1 reference

8 April 2019

Bunched sets a boundary for Notch signaling to pattern anterior eggshell structures during Drosophila oogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

R1/R6 cell differentiation

determination method

1 reference

8 April 2019

The HLH protein Extramacrochaetae is required for R7 cell and cone cell fates in the Drosophila eye.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

wing disc dorsal/ventral pattern formation

determination method

1 reference

8 April 2019

Influence of Notch on dorsoventral compartmentalization and actin organization in the Drosophila wing.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

lymph gland development

determination method

1 reference

8 April 2019

Evidence for a fruit fly hemangioblast and similarities between lymph-gland hematopoiesis in fruit fly and mammal aorta-gonadal-mesonephros mesoderm.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

compound eye development

determination method

3 references

8 April 2019

Selector and signalling molecules cooperate in organ patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

The JAK/STAT pathway and Drosophila development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

On the mechanism underlying the divergent retinal and bristle defects of M8* (E(spl)D) in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

imaginal disc-derived male genitalia morphogenesis

determination method

1 reference

8 April 2019

UVRAG is required for organ rotation by regulating Notch endocytosis in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

stem cell differentiation

determination method

1 reference

8 April 2019

Stem cells signal to the niche through the Notch pathway in the Drosophila ovary.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

regulation of neurogenesis

determination method

1 reference

8 April 2019

Notch mRNA expression in Drosophila embryos is negatively regulated at the level of mRNA 3' processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

regulation of developmental process

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

nervous system process

determination method

1 reference

8 April 2019

Requirement of Notch in adulthood for neurological function and longevity.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

regulation of filopodium assembly

determination method

1 reference

8 April 2019

How Notch establishes longitudinal axon connections between successive segments of the Drosophila CNS.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

germ-line stem-cell niche homeostasis

determination method

1 reference

8 April 2019

Notch signaling mediates the age-associated decrease in adhesion of germline stem cells to the niche

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

formation of a compartment boundary

determination method

1 reference

8 April 2019

Notch-mediated repression of bantam miRNA contributes to boundary formation in the Drosophila wing.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

compartment boundary maintenance

determination method

1 reference

8 April 2019

Notch-dependent epithelial fold determines boundary formation between developmental fields in the Drosophila antenna.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

morphogenesis of an epithelial fold

determination method

1 reference

8 April 2019

Notch-dependent epithelial fold determines boundary formation between developmental fields in the Drosophila antenna.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

epithelial cell proliferation involved in Malpighian tubule morphogenesis

determination method

1 reference

8 April 2019

A genetic hierarchy establishes mitogenic signalling and mitotic competence in the renal tubules of Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

Malpighian tubule tip cell differentiation

determination method

1 reference

8 April 2019

Multiple signalling pathways establish cell fate and cell number in Drosophila malpighian tubules.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

positive regulation of G1/S transition of mitotic cell cycle

determination method

1 reference

8 April 2019

Extracellular signals responsible for spatially regulated proliferation in the differentiating Drosophila eye.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

regulation of neuroblast proliferation

determination method

3 references

8 April 2019

bHLH-O proteins balance the self-renewal and differentiation of Drosophila neural stem cells by regulating Earmuff expression.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Notch maintains Drosophila type II neuroblasts by suppressing expression of the Fez transcription factor Earmuff

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Notch maintains Drosophila type II neuroblasts by suppressing expression of the Fez transcription factor Earmuff

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

negative regulation of cell-cell adhesion mediated by cadherin

determination method

1 reference

8 April 2019

Notch signaling mediates the age-associated decrease in adhesion of germline stem cells to the niche

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

peripheral nervous system development

determination method

1 reference

8 April 2019

Notch signaling represses the glial fate in fly PNS.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

regulation of stem cell division

determination method

1 reference

8 April 2019

The sexual identity of adult intestinal stem cells controls organ size and plasticity.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

Notch signaling pathway

determination method

8 references

14 January 2019

Specific EGF repeats of Notch mediate interactions with Delta and serrate: Implications for notch as a multifunctional receptor

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

14 January 2019

The enhancer of split complex of Drosophila includes four Notch-regulated members of the bearded gene family

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

14 January 2019

The bHLH-PAS transcription factor dysfusion regulates tarsal joint formation in response to Notch activity during drosophila leg development

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

14 January 2019

Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

14 January 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

14 January 2019

Notch activation stimulates transient and selective binding of Su(H)/CSL to target enhancers

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

14 January 2019

The adhesion force of Notch with Delta and the rate of Notch signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07207&geneProductId=UniProtKB:P07207

determination method

neuron fate specification

determination method

1 reference

8 April 2019

Numb antagonizes Notch signaling to specify sibling neuron cell fates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

Notch signaling pathway

determination method

13 references

8 April 2019

The Notch locus and the genetic circuitry involved in early Drosophila neurogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Nicastrin controls aspects of photoreceptor neuron specification and differentiation in the Drosophila eye.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Specific EGF repeats of Notch mediate interactions with Delta and serrate: Implications for notch as a multifunctional receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

The enhancer of split complex of Drosophila includes four Notch-regulated members of the bearded gene family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

The bHLH-PAS transcription factor dysfusion regulates tarsal joint formation in response to Notch activity during drosophila leg development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Epsin-Dependent Ligand Endocytosis Activates Notch by Force.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

deltex, a locus interacting with the neurogenic genes, Notch, Delta and mastermind in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Notch activation stimulates transient and selective binding of Su(H)/CSL to target enhancers

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

The adhesion force of Notch with Delta and the rate of Notch signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Activation of the Notch Signaling Pathway In Vivo Elicits Changes in CSL Nuclear Dynamics.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

neuron fate determination

determination method

1 reference

8 April 2019

Mastermind acts downstream of notch to specify neuronal cell fates in the Drosophila central nervous system.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

positive regulation of gene expression

determination method

3 references

8 April 2019

bHLH-O proteins are crucial for Drosophila neuroblast self-renewal and mediate Notch-induced overproliferation.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

Notch maintains Drosophila type II neuroblasts by suppressing expression of the Fez transcription factor Earmuff

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

8 April 2019

A population of adult satellite-like cells in Drosophila is maintained through a switch in RNA-isoforms.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

muscle cell cellular homeostasis

determination method

1 reference

8 April 2019

A population of adult satellite-like cells in Drosophila is maintained through a switch in RNA-isoforms.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07207

determination method

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07207

Domain of unknown function DUF3454, notch

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07207

EGF-like calcium-binding, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07207

Notch, NOD domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07207

EGF-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07207

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07207

EGF-like, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07207

Notch, NODP domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07207

ankyrin repeat-containing domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07207

EGF-like calcium-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07207

EGF-type aspartate/asparagine hydroxylation site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07207

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Sitelinks

Wikipedia(0 entries)

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Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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