(Q29814813)

http://www.ebi.ac.uk/interpro/protein/P10083

InterPro Release 71.0

reference URL

Helix-loop-helix DNA-binding domain superfamily

1 reference

http://www.ebi.ac.uk/interpro/protein/P10083

InterPro Release 71.0

reference URL

Myc-type, basic helix-loop-helix (bHLH) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

RNA polymerase II transcription regulatory region sequence-specific DNA binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

DNA binding

deadpan, an essential pan-neural gene encoding an HLH protein, acts as a denominator in Drosophila sex determination

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

8 April 2019

sequence-specific DNA binding

Transcriptional activation by heterodimers of the achaete-scute and daughterless gene products of Drosophila

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

8 April 2019

Regulation of scute function by extramacrochaete in vitro and in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

8 April 2019

The Drosophila extramacrochaetae protein antagonizes sequence-specific DNA binding by daughterless/achaete-scute protein complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

protein heterodimerization activity

3 references

8 April 2019

Regulation of scute function by extramacrochaete in vitro and in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

8 April 2019

The Drosophila extramacrochaetae protein antagonizes sequence-specific DNA binding by daughterless/achaete-scute protein complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

8 April 2019

Transcriptional activation by heterodimers of the achaete-scute and daughterless gene products of Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

protein dimerization activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

1 reference

8 April 2019

protein binding

transcription factor binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

cell component

nucleus

1 reference

8 April 2019

Regulation of proneural gene expression and cell fate during neuroblast segregation in the Drosophila embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

transcription regulator complex

1 reference

8 April 2019

Transcriptional activation by heterodimers of the achaete-scute and daughterless gene products of Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

RNA polymerase II transcription regulator complex

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

regulation of antimicrobial peptide biosynthetic process

biological process

1 reference

10 September 2018

Genome-wide RNA interference in Drosophila cells identifies G protein-coupled receptor kinase 2 as a conserved regulator of NF-kappaB signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10083&geneProductId=UniProtKB:P10083

multicellular organism development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

1 reference

8 April 2019

regulation of mitotic cell cycle

1 reference

8 April 2019

Regulation of Cell Cycles in Drosophila Development: Intrinsic and Extrinsic Cues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

nervous system development

deadpan, an essential pan-neural gene encoding an HLH protein, acts as a denominator in Drosophila sex determination

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

8 April 2019

The role of class I HLH genes in neural development--have they been overlooked?

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

8 April 2019

neuroblast fate determination

1 reference

8 April 2019

Genetic control of Drosophila nerve cord development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

central nervous system development

1 reference

8 April 2019

Gene duplication at the achaete-scute complex and morphological complexity of the peripheral nervous system in Diptera

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

ventral cord development

1 reference

8 April 2019

Genetic control of Drosophila nerve cord development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

sensory organ development

1 reference

5 June 2018

Proneural proteins Achaete and Scute associate with nuclear actin to promote formation of external sensory organs

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10083&geneProductId=UniProtKB:P10083

chaeta morphogenesis

How to pattern an epithelium: lessons from achaete-scute regulation on the notum of Drosophila

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

8 April 2019

Are complex behaviors specified by dedicated regulatory genes? Reasoning from Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

8 April 2019

achaete, but not scute, is dispensable for the peripheral nervous system of Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

1 reference

8 April 2019

positive regulation of transcription, DNA-templated

1 reference

1 January 2018

Antagonism of notch signaling activity by members of a novel protein family encoded by the bearded and enhancer of split gene complexes.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10083&geneProductId=UniProtKB:P10083

regulation of neurogenesis

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

epithelial cell proliferation involved in Malpighian tubule morphogenesis

1 reference

8 April 2019

A genetic hierarchy establishes mitogenic signalling and mitotic competence in the renal tubules of Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

Malpighian tubule tip cell differentiation

1 reference

8 April 2019

Sequential fates in a single cell are established by the neurogenic cascade in the Malpighian tubules of Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

neuron differentiation

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

positive regulation of transcription by RNA polymerase II

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

positive regulation of antibacterial peptide biosynthetic process

1 reference

8 April 2019

Genome-wide RNA interference in Drosophila cells identifies G protein-coupled receptor kinase 2 as a conserved regulator of NF-kappaB signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10083

Myc-type, basic helix-loop-helix (bHLH) domain

has part(s)

1 reference