(Q29817921)

English

Groucho Dmel_CG8384

Protein found in Drosophila melanogaster

CG8384-PD
gro-PF
CG8384-PF
CG8384-PJ
CG8384-PE
CG8384-PA
CG8384-PG
gro-PE
gro-PD
gro
groucho
CG8384-PH
CG8384 gene product from transcript CG8384-RH
gro-PB
CG8384-PB
gro-PA
dgroucho
gro-PJ
gro-PI
CG8384-PI
gro-PG
gro-PC
CG8384-PC
gro-PH

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

WD40/YVTN repeat-like-containing domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16371

WD40-repeat-containing domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16371

Groucho/transducin-like enhancer

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16371

Groucho/TLE, N-terminal Q-rich domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

WD40 repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

WD40 repeat, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Drosophila melanogaster

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

transcription corepressor activity

determination method

1 reference

27 February 2018

Two modes of recruitment of E(spl) repressors onto target genes.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

determination method

1 reference

5 June 2018

Transcriptional repression: the long and the short of it.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

transcription corepressor activity

determination method

5 references

27 February 2018

Runt and Lozenge function in Drosophila development

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

27 February 2018

Transcriptional repression: the long and the short of it.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

27 February 2018

Structure, function and evolution of sex-determining systems in Dipteran insects

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

27 February 2018

Transcriptional coregulators in development.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

27 February 2018

Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

protein binding

determination method

15 references

8 April 2019

Elbow and Noc define a family of zinc finger proteins controlling morphogenesis of specific tracheal branches.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

8 April 2019

Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

8 April 2019

The WRPW motif of the hairy-related basic helix-loop-helix repressor proteins acts as a 4-amino-acid transcription repression and protein-protein interaction domain

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

8 April 2019

Groucho and dCtBP mediate separate pathways of transcriptional repression in the Drosophila embryo

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

8 April 2019

Degringolade, a SUMO-targeted ubiquitin ligase, inhibits Hairy/Groucho-mediated repression

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

8 April 2019

Groucho corepressor functions as a cofactor for the Knirps short-range transcriptional repressor

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

8 April 2019

A network of interacting transcriptional regulators involved in Drosophila neural fate specification revealed by the yeast two-hybrid system

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

8 April 2019

Six3-mediated auto repression and eye development requires its interaction with members of the Groucho-related family of co-repressors

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

8 April 2019

Hedgehog restricts its expression domain in the Drosophila wing

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

8 April 2019

A Myc-Groucho complex integrates EGF and Notch signaling to regulate neural development.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

8 April 2019

Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

8 April 2019

A protein interaction map of Drosophila melanogaster

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

8 April 2019

Groucho and dCtBP mediate separate pathways of transcriptional repression in the Drosophila embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

8 April 2019

Elbow and Noc define a family of zinc finger proteins controlling morphogenesis of specific tracheal branches.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

8 April 2019

Groucho corepressor functions as a cofactor for the Knirps short-range transcriptional repressor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

transcription factor binding

determination method

6 references

8 April 2019

Dorsal-mediated repression requires the formation of a multiprotein repression complex at the ventral silencer.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

8 April 2019

Partner specificity is essential for proper function of the SIX-type homeodomain proteins Sine oculis and Optix during fly eye development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

8 April 2019

Huckebein repressor activity in Drosophila terminal patterning is mediated by Groucho.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

8 April 2019

The Drosophila Nkx6 homeodomain protein has both activation and repression domains and can activate target gene expression.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

8 April 2019

Capicua DNA-binding sites are general response elements for RTK signaling in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

8 April 2019

Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

HMG box domain binding

determination method

1 reference

8 April 2019

Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

CRD domain binding

determination method

1 reference

8 April 2019

Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

transcription corepressor activity

determination method

6 references

5 June 2018

Runt and Lozenge function in Drosophila development

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

5 June 2018

Structure, function and evolution of sex-determining systems in Dipteran insects

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

5 June 2018

Transcriptional repression: the long and the short of it.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

5 June 2018

Transcriptional coregulators in development.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

5 June 2018

Two modes of recruitment of E(spl) repressors onto target genes.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

5 June 2018

Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

transcription corepressor activity

determination method

3 references

16 July 2018

Transcriptional coregulators in development.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

16 July 2018

Two modes of recruitment of E(spl) repressors onto target genes.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

16 July 2018

Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

transcription corepressor activity

determination method

4 references

8 April 2019

Transcriptional coregulators in development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

8 April 2019

Two modes of recruitment of E(spl) repressors onto target genes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

8 April 2019

Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

protein-containing complex

determination method

1 reference

8 April 2019

A Myc-Groucho complex integrates EGF and Notch signaling to regulate neural development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

determination method

4 references

14 January 2019

Cell fate specification in the Drosophila retina

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

14 January 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

14 January 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

transcription regulator complex

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

determination method

biological process

negative regulation of transcription by RNA polymerase II

determination method

4 references

5 June 2018

Runt and Lozenge function in Drosophila development

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

5 June 2018

Structure, function and evolution of sex-determining systems in Dipteran insects

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

5 June 2018

Groucho and dCtBP mediate separate pathways of transcriptional repression in the Drosophila embryo

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

5 June 2018

Origins of context-dependent gene repression by capicua

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

transcription, DNA-templated

determination method

1 reference

16 July 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

regulation of transcription, DNA-templated

determination method

3 references

8 April 2019

Groucho corepressor functions as a cofactor for the Knirps short-range transcriptional repressor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

8 April 2019

Groucho corepressor functions as a cofactor for the Knirps short-range transcriptional repressor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

multicellular organism development

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

sex determination, primary response to X:A ratio

determination method

1 reference

8 April 2019

Structure, function and evolution of sex-determining systems in Dipteran insects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

cell differentiation

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

negative regulation of smoothened signaling pathway

determination method

1 reference

10 September 2018

Hedgehog restricts its expression domain in the Drosophila wing

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

negative regulation of transcription, DNA-templated

determination method

3 references

5 June 2018

Transcriptional repression: the long and the short of it.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

5 June 2018

A Myc-Groucho complex integrates EGF and Notch signaling to regulate neural development.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

5 June 2018

Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

negative regulation of canonical Wnt signaling pathway

determination method

1 reference

16 July 2018

Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371

determination method

epidermal growth factor receptor signaling pathway

determination method

1 reference

8 April 2019

Phosphorylation of Groucho mediates RTK feedback inhibition and prolonged pathway target gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

fibroblast growth factor receptor signaling pathway

determination method

1 reference

8 April 2019

Phosphorylation of Groucho mediates RTK feedback inhibition and prolonged pathway target gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

negative regulation of Toll signaling pathway

determination method

1 reference

8 April 2019

The SUMO-targeted ubiquitin ligase, Dgrn, is essential for Drosophila innate immunity.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371

determination method

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16371

Groucho/TLE, N-terminal Q-rich domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16371

WD40 repeat, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16371

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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