(Q30009350)

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The small GTPase Rap1 promotes cell movement rather than stabilizes adhesion in epithelial cells responding to insulin-like growth factor I.

scientific article published in October 2014

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Europe PubMed Central

PubMed publication ID

21 May 2017

The small GTPase Rap1 promotes cell movement rather than stabilizes adhesion in epithelial cells responding to insulin-like growth factor I. (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 May 2017

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author name string

Marina A Guvakova

1

1 reference

Europe PubMed Central

PubMed publication ID

21 May 2017

William S Y Lee

2

1 reference

Europe PubMed Central

PubMed publication ID

21 May 2017

Dana K Furstenau

3

1 reference

Europe PubMed Central

PubMed publication ID

21 May 2017

Indira Prabakaran

4

1 reference

Europe PubMed Central

PubMed publication ID

21 May 2017

David C Li

5

1 reference

Europe PubMed Central

PubMed publication ID

21 May 2017

Rupert Hung

6

1 reference

Europe PubMed Central

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21 May 2017

Natasha Kushnir

7

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Europe PubMed Central

PubMed publication ID

21 May 2017

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publication date

1 October 2014

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Europe PubMed Central

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21 May 2017

number of pages

14

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Biochemical Journal

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Europe PubMed Central

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21 May 2017

463

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Europe PubMed Central

PubMed publication ID

21 May 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

21 May 2017

257-270

1 reference

Europe PubMed Central

PubMed publication ID

21 May 2017

Multiple roles of Rap1 in hematopoietic cells: complementary versus antagonistic functions

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

22 May 2017

A ras-related gene with transformation suppressor activity

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

22 May 2017

Local activation of Rap1 contributes to directional vascular endothelial cell migration accompanied by extension of microtubules on which RAPL, a Rap1-associating molecule, localizes

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

22 May 2017

Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

22 May 2017

Molecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advances

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

22 May 2017

Functional role of alpha-actinin, PI 3-kinase and MEK1/2 in insulin-like growth factor I receptor kinase regulated motility of human breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

22 May 2017

B-Raf acts via the ROCKII/LIMK/cofilin pathway to maintain actin stress fibers in fibroblasts

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

22 May 2017

Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

22 May 2017

GEFs and GAPs: critical elements in the control of small G proteins

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

22 May 2017

Dynasore, a cell-permeable inhibitor of dynamin

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

22 May 2017

Rap1-PDZ-GEF1 interacts with a neurotrophin receptor at late endosomes, leading to sustained activation of Rap1 and ERK and neurite outgrowth

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

22 May 2017

Mechanism of the spatio-temporal regulation of Ras and Rap1.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

22 May 2017

DOCK4, a GTPase activator, is disrupted during tumorigenesis

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

22 May 2017

Loss of Rap1GAP in papillary thyroid cancer

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

22 May 2017

C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

22 May 2017

Rap1 signalling: adhering to new models

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Rap1 GTPase: Functions, Regulation, and Malignancy

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Identification of tuberin, the tuberous sclerosis-2 product. Tuberin possesses specific Rap1GAP activity

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Aberrant G protein signaling in nervous system tumors.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Linking Rap to cell adhesion

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Characterization of a factor that stimulates hydrolysis of GTP bound to ras gene product p21 (GTPase-activating protein) and correlation of its activity to cell density

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Mitogenic and oncogenic properties of the small G protein Rap1b

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Microinjection of smg/rap1/Krev-1 p21 into Swiss 3T3 Cells Induces DNA Synthesis and Morphological Changes

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

The Drosophila roughened mutation: activation of a rap homolog disrupts eye development and interferes with cell determination

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

The Rap1 GTPase functions as a regulator of morphogenesis in vivo

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Rap1 GTPase regulation of adherens junction positioning and cell adhesion.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Regulation of Rap1 activity by RapGAP1 controls cell adhesion at the front of chemotaxing cells

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Cyclic AMP potentiates vascular endothelial cadherin-mediated cell-cell contact to enhance endothelial barrier function through an Epac-Rap1 signaling pathway

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

KRIT-1/CCM1 is a Rap1 effector that regulates endothelial cell cell junctions

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Rap1 regulates the formation of E-cadherin-based cell-cell contacts.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Rap1 regulates E-cadherin-mediated cell-cell adhesion

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Rap1 GTPase inhibits leukocyte transmigration by promoting endothelial barrier function

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Rap1 integrates tissue polarity, lumen formation, and tumorigenic potential in human breast epithelial cells

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Sequential activation of Rap1 and Rac1 small G proteins by PDGF locally at leading edges of NIH3T3 cells.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Ras pathway signaling on endomembranes

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Breast cancer cell migration is regulated through junctional adhesion molecule-A-mediated activation of Rap1 GTPase.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Ras-related protein 1 and the insulin-like growth factor type I receptor are associated with risk of progression in patients diagnosed with carcinoma in situ

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Structure and function of the type 1 insulin-like growth factor receptor.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

New insulin-like growth factor (IGF)-precursor sequences from mammalian genomes: the molecular evolution of IGFs and associated peptides in primates

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Roles of insulinlike growth factor 1 (IGF-1) and the IGF-1 receptor in epidermal growth factor-stimulated growth of 3T3 cells

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Insulin-like growth factors control cell migration in health and disease

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

The role of the insulin-like growth factor-I receptor in malignancy: an update

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Insulin-like Growth Factors as Regulators of Cell Motility Signaling Mechanisms

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Cofilin activity during insulin-like growth factor I-stimulated neuroblastoma cell motility.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

IGF-II induces rapid beta-catenin relocation to the nucleus during epithelium to mesenchyme transition

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Regulation of the RAP1/RAF-1/extracellularly regulated kinase-1/2 cascade and prolactin release by the phosphoinositide 3-kinase/AKT pathway in pituitary cells.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Rap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factors

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Rap1 up-regulation and activation on plasma membrane regulates T cell adhesion.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Rap1 regulation of RIAM and cell adhesion.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Insulin receptor structure and its implications for the IGF-1 receptor

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Ras and Rap1: two highly related small GTPases with distinct function

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Insulin-like growth factor-I receptor internalization regulates signaling via the Shc/mitogen-activated protein kinase pathway, but not the insulin receptor substrate-1 pathway

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Amantadine and dansylcadaverine inhibit vesicular stomatitis virus uptake and receptor-mediated endocytosis of alpha 2-macroglobulin

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Protein-tyrosine phosphatase 1B associates with insulin receptor and negatively regulates insulin signaling without receptor internalization

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Insulin-like growth factor type-I receptor internalization and recycling mediate the sustained phosphorylation of Akt.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Expression and function of the insulin receptor substrate proteins in cancer

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Grb10/Nedd4-mediated multiubiquitination of the insulin-like growth factor receptor regulates receptor internalization

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

The diaphanous-related formin mDia1 controls serum response factor activity through its effects on actin polymerization

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Modulation of acto-myosin contractility in skeletal muscle myoblasts uncouples growth arrest from differentiation

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Rap1: a key regulator in cell-cell junction formation

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Cell-cell junction formation: the role of Rap1 and Rap1 guanine nucleotide exchange factors

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Activation of Rap1 promotes prostate cancer metastasis

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

EGFR-dependent pancreatic carcinoma cell metastasis through Rap1 activation

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Spatio-temporal images of growth-factor-induced activation of Ras and Rap1.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Amplification, up-regulation and over-expression of C3G (CRK SH3 domain-binding guanine nucleotide-releasing factor) in non-small cell lung cancers

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Selective Effects of Inhibitors of Hormone Processing on Insulin Action in Isolated Hepatocytes*

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Roles of fascin in human carcinoma motility and signaling: prospects for a novel biomarker?

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Stimulation of fascin spikes by thrombospondin-1 is mediated by the GTPases Rac and Cdc42

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Dual actin-bundling and protein kinase C-binding activities of fascin regulate carcinoma cell migration downstream of Rac and contribute to metastasis

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Latrunculins: novel marine toxins that disrupt microfilament organization in cultured cells

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Induction of fascin spikes in breast cancer cells by activation of the insulin-like growth factor-I receptor

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Enhancement of guanine-nucleotide exchange activity of C3G for Rap1 by the expression of Crk, CrkL, and Grb2

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Transglutaminase is essential in receptor-mediated endocytosis of α2-macroglobulin and polypeptide hormones

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131638

21 January 2018

Identifiers

10.1042/BJ20131638

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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