(Q30168316)

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A motif-based profile scanning approach for genome-wide prediction of signaling pathways

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scholarly article

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Europe PubMed Central

9 June 2017

A motif-based profile scanning approach for genome-wide prediction of signaling pathways (English)

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Europe PubMed Central

9 June 2017

Stefano Volinia

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S Volinia

5

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M B Yaffe

1

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9 June 2017

G G Leparc

2

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9 June 2017

J Lai

3

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9 June 2017

T Obata

4

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9 June 2017

L C Cantley

6

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9 June 2017

publication date

1 April 2001

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9 June 2017

Nature Biotechnology

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9 June 2017

19

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9 June 2017

348-353

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9 June 2017

4

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9 June 2017

Protein modules and signalling networks

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Improving the sensitivity of the sequence profile method

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https://api.crossref.org/works/10.1038%2F86737

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Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

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SMART: identification and annotation of domains from signalling and extracellular protein sequences

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The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000.

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SH2 domains recognize specific phosphopeptide sequences

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Recognition of unique carboxyl-terminal motifs by distinct PDZ domains

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The structural basis for 14-3-3:phosphopeptide binding specificity

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Pfam 3.1: 1313 multiple alignments and profile HMMs match the majority of proteins

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Conformation of amino acid side-chains in proteins

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Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane

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Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

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The phosphotyrosine interaction domain of Shc binds an LXNPXY motif on the epidermal growth factor receptor

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Basic local alignment search tool

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Peptide and protein library screening defines optimal substrate motifs for AKT/PKB.

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PROSITE: a dictionary of sites and patterns in proteins

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

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Three-dimensional structure of the tyrosine kinase c-Src

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PhosphoBase, a database of phosphorylation sites: release 2.0.

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The use of gene clusters to infer functional coupling

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Cluster analysis and display of genome-wide expression patterns

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Protein interaction maps for complete genomes based on gene fusion events

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A combined algorithm for genome-wide prediction of protein function

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Mapping specificity determinants for protein-protein association using protein fusions and random peptide libraries

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Europe PubMed Central

9 June 2017

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Europe PubMed Central

9 June 2017

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