(Q30194559)

10 June 2017

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title

The GRB2/Sem-5 adaptor protein (English)

1 reference

10 June 2017

1

1 reference

PubMed ID

8307166

10 June 2017

language of work or name

English

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publication date

1 January 1994

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10 June 2017

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10 June 2017

338

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10 June 2017

113-117

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10 June 2017

2

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Regulatory mechanisms for ras proteins

10 June 2017

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

Function and regulation of ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

Nerve growth factor stimulation of the Ras-guanine nucleotide exchange factor and GAP activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

Epidermal growth factor regulates the exchange rate of guanine nucleotides on p21ras in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

Ras activation by insulin and epidermal growth factor through enhanced exchange of guanine nucleotides on p21ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

The let-23 gene necessary for Caenorhabditis elegans vulval induction encodes a tyrosine kinase of the EGF receptor subfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

let-60, a gene that specifies cell fates during C. elegans vulval induction, encodes a ras protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

A novel viral oncogene with structural similarity to phospholipase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

Identification of a ten-amino acid proline-rich SH3 binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

Cloning of ASH, a ubiquitous protein composed of one Src homology region (SH) 2 and two SH3 domains, from human and rat cDNA libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

Molecular cloning of the mouse grb2 gene: differential interaction of the Grb2 adaptor protein with epidermal growth factor and nerve growth factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

Genetic dissection of a neurodevelopmental pathway: Son of sevenless functions downstream of the sevenless and EGF receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

Signalling by the sevenless protein tyrosine kinase is mimicked by Ras1 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

An SH3-SH2-SH3 protein is required for p21Ras1 activation and binds to sevenless and Sos proteins in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

Identification of murine homologues of the Drosophila son of sevenless gene: potential activators of ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

The function of GRB2 in linking the insulin receptor to Ras signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

Binding of the Ras activator son of sevenless to insulin receptor substrate-1 signaling complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

SH3 domains direct cellular localization of signaling molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

Stimulation of p21 ras upon T-cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

The GTPase dynamin binds to and is activated by a subset of SH3 domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

Caenorhabditis elegans ras gene let-60 acts as a switch in the pathway of vulval induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2894%2980346-3

10.1016/0014-5793(94)80346-3

21 January 2018

Identifiers

DOI

1 reference

10 June 2017

1 reference

PubMed ID

8307166