(Q30309202)

16 June 2017

1 reference

title

Adhesion assembly, disassembly and turnover in migrating cells -- over and over and over again (English)

1 reference

substrate-dependent cell migration

16 June 2017

1 reference

substrate-bound cell migration, adhesion receptor recycling

GO:0006929

1 reference

substrate-dependent cell migration, cell attachment to substrate

GO:0006934

1 reference

substrate-dependent cell migration, cell contraction

GO:0006931

1 reference

negative regulation of cell adhesion involved in substrate-bound cell migration

GO:0006932

1 reference

substrate-dependent cell migration, cell extension

GO:0006933

1 reference

Donna J Webb

1

1 reference

16 June 2017

J Thomas Parsons

series ordinal

2

1 reference

16 June 2017

Alan F Horwitz

series ordinal

3

1 reference

16 June 2017

1 April 2002

1 reference

16 June 2017

1 reference

16 June 2017

4

1 reference

16 June 2017

E97-100

1 reference

16 June 2017

4

1 reference

https://scigraph.springernature.com/pub.10.1038/ncb0402-e97

16 June 2017

0 references

cites work

Cell migration: a physically integrated molecular process

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Temporal and spatial distribution of activated Pak1 in fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Localized Rac activation dynamics visualized in living cells

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Cell migration by graded attachment to substrates and contraction

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Principles of locomotion for simple-shaped cells

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Exchange of actin subunits at the leading edge of living fibroblasts: possible role of treadmilling

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

An actin-nucleating activity in polymorphonuclear leukocytes is modulated by chemotactic peptides

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Actin machinery: pushing the envelope.

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Focal adhesions, contractility, and signaling

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function.

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Integrin transmembrane signaling and cytoskeletal control

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Integrin function: molecular hierarchies of cytoskeletal and signaling molecules

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Bidirectional signaling between the cytoskeleton and integrins

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Nascent focal adhesions are responsible for the generation of strong propulsive forces in migrating fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

A micromachined device provides a new bend on fibroblast traction forces

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Traction forces generated by locomoting keratocytes

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Separation of propulsive and adhesive traction stresses in locomoting keratocytes

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Integrin dynamics and matrix assembly: tensin-dependent translocation of alpha(5)beta(1) integrins promotes early fibronectin fibrillogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Dynamics and segregation of cell–matrix adhesions in cultured fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Interplay between Rac and Rho in the control of substrate contact dynamics

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Analysis of the actin-myosin II system in fish epidermal keratocytes: mechanism of cell body translocation

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Forces on adhesive contacts affect cell function

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Focal adhesions: a nexus for intracellular signaling and cytoskeletal dynamics

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Assembly and mechanosensory function of focal contacts

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Assembling an actin cytoskeleton for cell attachment and movement

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

A WASp-VASP complex regulates actin polymerization at the plasma membrane.

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily conserved proteins

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Zyxin is not colocalized with vasodilator-stimulated phosphoprotein (VASP) at lamellipodial tips and exhibits different dynamics to vinculin, paxillin, and VASP in focal adhesions

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Differential dynamics of alpha 5 integrin, paxillin, and alpha-actinin during formation and disassembly of adhesions in migrating cells

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Rac recruits high-affinity integrin alphavbeta3 to lamellipodia in endothelial cell migration

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Visualizing muscle cell migration in situ.

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Mutational evidence for control of cell adhesion through integrin diffusion/clustering, independent of ligand binding

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Evidence for an actin-containing cytoplasmic precursor of the focal contact and the timing of incorporation of vinculin at the focal contact.

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

A precursor of the focal contact in cultured fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Dynamics of beta 1 integrin-mediated adhesive contacts in motile fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Tyrosine phosphorylation and cytoskeletal tension regulate the release of fibroblast adhesions

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Focal adhesion motility revealed in stationary fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Marching at the front and dragging behind: differential alphaVbeta3-integrin turnover regulates focal adhesion behavior

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Differential effects of PAK1-activating mutations reveal activity-dependent and -independent effects on cytoskeletal regulation

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

A role for p21-activated kinase in endothelial cell migration.

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Inhibition of myosin light chain kinase by p21-activated kinase

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

RhoA is required for monocyte tail retraction during transendothelial migration

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Rho-kinase inhibitor retards migration and in vivo dissemination of human prostate cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

PAKa, a putative PAK family member, is required for cytokinesis and the regulation of the cytoskeleton in Dictyostelium discoideum cells during chemotaxis

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: a role for paxillin tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Induced focal adhesion kinase (FAK) expression in FAK-null cells enhances cell spreading and migration requiring both auto- and activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of Pyk2.

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Src family kinases are required for integrin but not PDGFR signal transduction.

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Ca2+- and calcineurin-dependent recycling of an integrin to the front of migrating neutrophils

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Protein tyrosine phosphatase-PEST regulates focal adhesion disassembly, migration, and cytokinesis in fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

p130(Cas), an assembling molecule of actin filaments, promotes cell movement, cell migration, and cell spreading in fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Regulation of integrin-mediated adhesion during cell migration

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Regulation of cell migration by the calcium-dependent protease calpain

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Epidermal growth factor receptor activation of calpain is required for fibroblast motility and occurs via an ERK/MAP kinase signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Reduced cell migration and disruption of the actin cytoskeleton in calpain-deficient embryonic fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Microtubule targeting of substrate contacts promotes their relaxation and dissociation

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Enforced polarisation and locomotion of fibroblasts lacking microtubules

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

An increase or a decrease in myosin II phosphorylation inhibits macrophage motility

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Relationship between receptor/ligand binding affinity and adhesion strength

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Adhesion mediated by bonds in series.

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Dynamic strength of molecular adhesion bonds

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Membrane traffic during cell locomotion

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Endocytosis: relation to capping and cell locomotion

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Targeting, capture, and stabilization of microtubules at early focal adhesions

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

p95-APP1 links membrane transport to Rac-mediated reorganization of actin.

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

ARF1 mediates paxillin recruitment to focal adhesions and potentiates Rho-stimulated stress fiber formation in intact and permeabilized Swiss 3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

A new paxillin-binding protein, PAG3/Papalpha/KIAA0400, bearing an ADP-ribosylation factor GTPase-activating protein activity, is involved in paxillin recruitment to focal adhesions and cell migration

1 reference

https://api.crossref.org/works/10.1038%2FNCB0402-E97

7 January 2021

Identifiers

DOI

10.1038/NCB0402-E97

1 reference

Dimensions Publication ID

16 June 2017

0 references

1 reference