(Q30310839)

16 June 2017

Synergistic promotion of c-Src activation and cell migration by Cas and AND-34/BCAR3. (English)

1 reference

16 June 2017

Rebecca B Riggins

1

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author name string

Lawrence A Quilliam

series ordinal

2

1 reference

PubMed ID

12740391

16 June 2017

Amy H Bouton

series ordinal

3

1 reference

PubMed ID

12740391

16 June 2017

language of work or name

English

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publication date

11 May 2003

1 reference

Journal of Biological Chemistry

16 June 2017

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16 June 2017

278

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16 June 2017

28264-28273

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16 June 2017

30

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Integrin signalling: a new Cas(t) of characters enters the stage

16 June 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Functions of the adapter protein Cas: signal convergence and the determination of cellular responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Stable association of activated pp60src with two tyrosine-phosphorylated cellular proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Binding of Transforming Protein, P47 gag-crk , to a Broad Range of Phosphotyrosine-containing Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Identification of two focal adhesion targeting sequences in the adapter molecule p130(Cas).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

A small-molecule inhibitor of skeletal muscle myosin II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Focal adhesions - the cytoskeletal connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Integrin-mediated cell adhesion promotes tyrosine phosphorylation of p130Cas, a Src homology 3-containing molecule having multiple Src homology 2-binding motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Tyrosine phosphorylation of p130Cas and cortactin accompanies integrin-mediated cell adhesion to extracellular matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Complexes of focal adhesion kinase (FAK) and Crk-associated substrate (p130(Cas)) are elevated in cytoskeleton-associated fractions following adhesion and Src transformation. Requirements for Src kinase activity and FAK proline-rich motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

CAS/Crk coupling serves as a "molecular switch" for induction of cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Extracellular-regulated kinase activation and CAS/Crk coupling regulate cell migration and suppress apoptosis during invasion of the extracellular matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Differential regulation of cell migration, actin stress fiber organization, and cell transformation by functional domains of Crk-associated substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Direct binding of C-terminal region of p130Cas to SH2 and SH3 domains of Src kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Selected glimpses into the activation and function of Src kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Src family kinases are required for integrin but not PDGFR signal transduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

SRC catalytic but not scaffolding function is needed for integrin-regulated tyrosine phosphorylation, cell migration, and cell spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Focal adhesions require catalytic activity of Src family kinases to mediate integrin-matrix adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Src kinase plays an essential role in integrin-mediated tyrosine phosphorylation of Crk-associated substrate p130Cas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Mechanisms of CAS substrate domain tyrosine phosphorylation by FAK and Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Regulation of c-SRC activity and function by the adapter protein CAS

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

c-Src signaling induced by the adapters Sin and Cas is mediated by Rap1 GTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Processive phosphorylation of p130Cas by Src depends on SH3-polyproline interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

NSP1 defines a novel family of adaptor proteins linking integrin and tyrosine kinase receptors to the c-Jun N-terminal kinase/stress-activated protein kinase signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Novel function of Chat in controlling cell adhesion via Cas-Crk-C3G-pathway-mediated Rap1 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

p130Cas regulates the activity of AND-34, a novel Ral, Rap1, and R-Ras guanine nucleotide exchange factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

All in the family? New insights and questions regarding interconnectivity of Ras, Rap1 and Ral.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Rap1 signalling: adhering to new models

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

The Ras branch of small GTPases: Ras family members don't fall far from the tree

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Characterization of human epidermal growth factor receptor and c-Src interactions in human breast tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Bcar1/p130Cas protein and primary breast cancer: prognosis and response to tamoxifen treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Identification of BCAR3 by a random search for genes involved in antiestrogen resistance of human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Augmented mitogenic responsiveness to epidermal growth factor in murine fibroblasts that overexpress pp60c-src

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Detection of distinct pools of the adapter protein p130CAS using a panel of monoclonal antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

The role of SRC-CAS interactions in cellular transformation: ectopic expression of the carboxy terminus of CAS inhibits SRC-CAS interaction but has no effect on cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Mechanism of biological synergy between cellular Src and epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

R-Ras is regulated by activators and effectors distinct from those that control Ras function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

c-Raf-mediated inhibition of epidermal growth factor-stimulated cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Dimerization of the docking/adaptor protein HEF1 via a carboxy-terminal helix-loop-helix domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Proteolysis of the docking protein HEF1 and implications for focal adhesion dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Activation of C3G guanine nucleotide exchange factor for Rap1 by phosphorylation of tyrosine 504.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Induction of rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm) following phosphorylation by the nonreceptor tyrosine kinase Src.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

The GTPase Rap1 controls functional activation of macrophage integrin alphaMbeta2 by LPS and other inflammatory mediators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Rap1 is a potent activation signal for leukocyte function-associated antigen 1 distinct from protein kinase C and phosphatidylinositol-3-OH kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

The small GTPase, Rap1, mediates CD31-induced integrin adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Activation and function of the Rap1 GTPase in B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Src family protein tyrosine kinases: cooperating with growth factor and adhesion signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Relationships between Rap1b, affinity modulation of integrin alpha IIbbeta 3, and the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

An EGF receptor/Ral-GTPase signaling cascade regulates c-Src activity and substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

The Rap GTPases regulate B cell migration toward the chemokine stromal cell-derived factor-1 (CXCL12): potential role for Rap2 in promoting B cell migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Regulation of cell contraction and membrane ruffling by distinct signals in migratory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

CD98 induces LFA-1-mediated cell adhesion in lymphoid cells via activation of Rap1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

A growing family of guanine nucleotide exchange factors is responsible for activation of ras-family GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Crk family adaptors-signalling complex formation and biological roles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

Adhesion assembly, disassembly and turnover in migrating cells -- over and over and over again

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303535200

21 January 2018

Identifiers

DOI

10.1074/JBC.M303535200

1 reference

16 June 2017

1 reference

PubMed ID

12740391