(Q30406301)

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Mass spectrometry-based proteomics of human cannabinoid receptor 2: covalent cysteine 6.47(257)-ligand interaction affording megagonist receptor activation

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

5 September 2017

Mass spectrometry-based proteomics of human cannabinoid receptor 2: covalent cysteine 6.47(257)-ligand interaction affording megagonist receptor activation (English)

1 reference

Europe PubMed Central

PMC publication ID

5 September 2017

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cannabinoid receptor

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Alexandros Makriyannis

11

object named as

Alexandros Makriyannis

1 reference

Europe PubMed Central

PMC publication ID

5 September 2017

4

object named as

Nikolai Zvonok

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Europe PubMed Central

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5 September 2017

author name string

Dennis W Szymanski

1

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Europe PubMed Central

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5 September 2017

Malvina Papanastasiou

2

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Europe PubMed Central

PMC publication ID

5 September 2017

Katja Melchior

3

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Europe PubMed Central

PMC publication ID

5 September 2017

Richard W Mercier

5

1 reference

Europe PubMed Central

PMC publication ID

5 September 2017

David R Janero

6

1 reference

Europe PubMed Central

PMC publication ID

5 September 2017

Ganesh A Thakur

7

1 reference

Europe PubMed Central

PMC publication ID

5 September 2017

Sangwon Cha

8

1 reference

Europe PubMed Central

PMC publication ID

5 September 2017

Billy Wu

9

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Europe PubMed Central

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5 September 2017

Barry Karger

10

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Europe PubMed Central

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5 September 2017

publication date

13 September 2011

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Europe PubMed Central

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5 September 2017

Journal of Proteome Research

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Europe PubMed Central

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5 September 2017

10

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Europe PubMed Central

PMC publication ID

5 September 2017

10

1 reference

Europe PubMed Central

PMC publication ID

5 September 2017

4789-4798

1 reference

Europe PubMed Central

PMC publication ID

5 September 2017

Biophysical characterization of G-protein coupled receptor-peptide ligand binding

1 reference

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20 June 2018

Pharmacological characterization of AM1710, a putative cannabinoid CB2 agonist from the cannabilactone class: antinociception without central nervous system side-effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189276

20 June 2018

hCB2 ligand-interaction landscape: cysteine residues critical to biarylpyrazole antagonist binding motif and receptor modulation

1 reference

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20 June 2018

Approaches and Applications of Quantitative LC-MS for Proteomics and Activitomics

1 reference

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Dimerization and ligand binding affect the structure network of A(2A) adenosine receptor

1 reference

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20 June 2018

Recent progress in the structure determination of GPCRs, a membrane protein family with high potential as pharmaceutical targets

1 reference

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20 June 2018

Immunoregulation of a CB2 receptor agonist in a murine model of neuroAIDS

1 reference

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20 June 2018

Protein chemical modification on endogenous amino acids.

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20 June 2018

Cannabinoid CB(2) receptors in health and disease.

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20 June 2018

Endocannabinoid binding to the cannabinoid receptors: what is known and what remains unknown

1 reference

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20 June 2018

Recent advances in the production of proteins in insect and mammalian cells for structural biology

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20 June 2018

Unraveling the structure and function of G protein-coupled receptors through NMR spectroscopy.

1 reference

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20 June 2018

A conserved aromatic lock for the tryptophan rotameric switch in TM-VI of seven-transmembrane receptors

1 reference

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20 June 2018

The impact of GPCR structures on pharmacology and structure-based drug design

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20 June 2018

Purification of recombinant G-protein-coupled receptors

1 reference

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20 June 2018

Immobilized-metal affinity chromatography (IMAC): a review

1 reference

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20 June 2018

Endocannabinoid system: An overview of its potential in current medical practice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189276

20 June 2018

The endocannabinoid system: its general strategy of action, tools for its pharmacological manipulation and potential therapeutic exploitation

1 reference

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20 June 2018

From purified GPCRs to drug discovery: the promise of protein-based methodologies

1 reference

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20 June 2018

Multiple reaction monitoring-based, multiplexed, absolute quantitation of 45 proteins in human plasma

1 reference

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20 June 2018

Structural biology of human cannabinoid receptor-2 helix 6 in membrane-mimetic environments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189276

20 June 2018

Pharmacotherapeutic modulation of the endocannabinoid signalling system in psychiatric disorders: drug-discovery strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189276

20 June 2018

Current affairs in quantitative targeted proteomics: multiple reaction monitoring-mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189276

20 June 2018

Emerging strategies for exploiting cannabinoid receptor agonists as medicines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189276

20 June 2018

Multiple reaction monitoring for quantitative biomarker analysis in proteomics and metabolomics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189276

20 June 2018

Ligand-binding architecture of human CB2 cannabinoid receptor: evidence for receptor subtype-specific binding motif and modeling GPCR activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189276

20 June 2018

Covalent inhibitors of human monoacylglycerol lipase: ligand-assisted characterization of the catalytic site by mass spectrometry and mutational analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189276

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Over-expression, solubilization, and purification of G protein-coupled receptors for structural biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189276

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A2A adenosine receptor and its modulators: overview on a druggable GPCR and on structure-activity relationship analysis and binding requirements of agonists and antagonists

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189276

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Cannabinoid CB1 and CB2 receptor ligand specificity and the development of CB2-selective agonists.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189276

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Targeting the cannabinoid CB2 receptor: modelling and structural determinants of CB2 selective ligands

1 reference

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20 June 2018

Meta-analysis of cannabinoid ligand binding affinity and receptor distribution: interspecies differences.

1 reference

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20 June 2018

AM1241, a cannabinoid CB2 receptor selective compound, delays disease progression in a mouse model of amyotrophic lateral sclerosis

1 reference

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Recombinant G protein-coupled receptors from expression to renaturation: a challenge towards structure

1 reference

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20 June 2018

Cannabinoid signalling

1 reference

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189276

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189276

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Comprehensive proteomic mass spectrometric characterization of human cannabinoid CB2 receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189276

26 November 2018

(-)-7'-Isothiocyanato-11-hydroxy-1',1'-dimethylheptylhexahydrocannabinol (AM841), a high-affinity electrophilic ligand, interacts covalently with a cysteine in helix six and activates the CB1 cannabinoid receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189276

26 November 2018

Purification and mass spectroscopic analysis of human CB2 cannabinoid receptor expressed in the baculovirus system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189276

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Cannabinoid receptor antagonists: pharmacological opportunities, clinical experience, and translational prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21861534

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Azido- and isothiocyanato-substituted aryl pyrazoles bind covalently to the CB1 cannabinoid receptor and impair signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/21861534

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/PR2005583

1 reference

Europe PubMed Central

PMC publication ID

5 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

5 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

5 September 2017

ResearchGate publication ID

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