(Q30441879)

English

Transformation by pp60src or stimulation of cells with epidermal growth factor induces the stable association of tyrosine-phosphorylated cellular proteins with GTPase-activating protein

scientific article published on February 1, 1991

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scholarly article

1 reference

Europe PubMed Central

15 August 2017

Transformation by pp60src or stimulation of cells with epidermal growth factor induces the stable association of tyrosine-phosphorylated cellular proteins with GTPase-activating protein (English)

1 reference

Europe PubMed Central

15 August 2017

phosphorylation

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1 reference

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3 November 2022

1 reference

10.1128/MCB.11.2.945-953.1991

https://api.crossref.org/works/10.1128/MCB.11.2.945-953.1991

3 November 2022

author name string

A. H. Bouton

1

1 reference

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3 November 2022

S. B. Kanner

2

1 reference

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3 November 2022

R. R. Vines

3

1 reference

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3 November 2022

H. C. Wang

4

1 reference

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3 November 2022

J. B. Gibbs

5

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3 November 2022

J. T. Parsons

6

1 reference

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3 November 2022

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publication date

1 February 1991

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15 August 2017

full work available at URL

http://mcb.asm.org/cgi/content/abstract/11/2/945

online access status

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3 November 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1703633/?tool=EBI

online access status

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3 November 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1703633/pdf/?tool=EBI

Portable Document Format

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3 November 2022

https://europepmc.org/articles/PMC359756

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Europe PubMed Central

1 reference

Europe PubMed Central

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3 November 2022

https://europepmc.org/articles/PMC359756?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1703633

3 November 2022

https://journals.asm.org/doi/pdf/10.1128/mcb.11.2.945-953.1991

1 reference

10.1128/MCB.11.2.945-953.1991

https://api.crossref.org/works/10.1128/MCB.11.2.945-953.1991

3 November 2022

Molecular and Cellular Biology

1 reference

Europe PubMed Central

15 August 2017

11

1 reference

Europe PubMed Central

15 August 2017

945-953

1 reference

Europe PubMed Central

15 August 2017

2

1 reference

Europe PubMed Central

15 August 2017

Transformation of NIH 3T3 cells by microinjection of Ha-ras p21 protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

A short sequence in the p60src N terminus is required for p60src myristylation and membrane association and for cell transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Cell transformation by pp60c-src mutated in the carboxy-terminal regulatory domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Non-catalytic domains of cytoplasmic protein-tyrosine kinases: regulatory elements in signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

A noncatalytic domain conserved among cytoplasmic protein-tyrosine kinases modifies the kinase function and transforming activity of Fujinami sarcoma virus P130gag-fps

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

The absence of myristic acid decreases membrane binding of p60src but does not affect tyrosine protein kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Mutation of NH2-terminal glycine of p60src prevents both myristoylation and morphological transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Myristic acid, a rare fatty acid, is the lipid attached to the transforming protein of Rous sarcoma virus and its cellular homolog

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Requirement for c-ras proteins during viral oncogene transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Cloning of bovine GAP and its interaction with oncogenic ras p21.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Sequence similarity of phospholipase C with the non-catalytic region of src.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Activation of the oncogenic potential of the avian cellular src protein by specific structural alteration of the carboxy terminus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Linker insertion-deletion mutagenesis of the v-src gene: isolation of host- and temperature-dependent mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

ras GTPase activating protein: signal transmitter and signal terminator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Deletions and insertions within an amino-terminal domain of pp60v-src inactivate transformation and modulate membrane stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Src homology 2 domain deletion mutants of p60v-src do not phosphorylate cellular proteins of 120-150 kDa.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Genetics of src: structure and functional organization of a protein tyrosine kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

PDGF induction of tyrosine phosphorylation of GTPase activating protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Stable association of activated pp60src with two tyrosine-phosphorylated cellular proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

pp60c-src tyrosine kinase, myristylation, and modulatory domains are required for enhanced mitogenic responsiveness to epidermal growth factor seen in cells overexpressing c-src

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Deletions within the amino-terminal half of the c-src gene product that alter the functional activity of the protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Transformation-specific tyrosine phosphorylation of a novel cellular protein in chicken cells expressing oncogenic variants of the avian cellular src gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Novel tyrosine phosphorylations accompany the activation of pp60c-src during chemical carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Activation of pp60c-src transforming potential by mutations altering the structure of an amino terminal domain containing residues 90-95.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Phosphorylation of cellular proteins in Rous sarcoma virus-infected cells: analysis by use of anti-phosphotyrosine antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

A mutation in v-src that removes a single conserved residue in the SH-2 domain of pp60v-src restricts transformation in a host-dependent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Activation of pp60c-src tyrosine kinase specific activity in tumor-derived Syrian hamster embryo cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Identification of multiple novel polypeptide substrates of the v-src, v-yes, v-fps, v-ros, and v-erb-B oncogenic tyrosine protein kinases utilizing antisera against phosphotyrosine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Nonmyristoylated p60v-src fails to phosphorylate proteins of 115-120 kDa in chicken embryo fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

A novel viral oncogene with structural similarity to phospholipase C

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Augmented mitogenic responsiveness to epidermal growth factor in murine fibroblasts that overexpress pp60c-src

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Cell transformation by the viral src oncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Dephosphorylation or antibody binding to the carboxy terminus stimulates pp60c-src

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Activation of the pp60c-src kinase by middle T antigen binding or by dephosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Src homology region 2 domains direct protein-protein interactions in signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Binding of GAP to activated PDGF receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

PDGF beta-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Activation of the proto-oncogene p60c-src by point mutations in the SH2 domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Site-directed mutagenesis of the SH2- and SH3-coding domains of c-src produces varied phenotypes, including oncogenic activation of p60c-src

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Tyrosine phosphorylation of a 120-kilodalton pp60src substrate upon epidermal growth factor and platelet-derived growth factor receptor stimulation and in polyomavirus middle-T-antigen-transformed cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Phosphorylation and activation of epidermal growth factor receptors in cells transformed by the src oncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359756

20 June 2018

Oligonucleotide-Directed Mutagenesis: A Simple Method Using Two Oligonucleotide Primers and a Single-Stranded DNA Template

1 reference

https://pubmed.ncbi.nlm.nih.gov/1703633

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning of two types of GAP complementary DNA from human placenta

1 reference

https://pubmed.ncbi.nlm.nih.gov/1703633

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural features of the carboxy terminus of p60c-src that are required for the regulation of its intrinsic kinase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/1703633

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.11.2.945

1 reference

Europe PubMed Central

15 August 2017

10.1128/MCB.11.2.945-953.1991

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1703633

3 November 2022

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

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