(Q30448767)

20 September 2017

Overcoming cellular senescence in human cancer pathogenesis (English)

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20 September 2017

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T R Yeager

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20 September 2017

S DeVries

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20 September 2017

D F Jarrard

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20 September 2017

C Kao

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20 September 2017

S Y Nakada

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20 September 2017

T D Moon

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20 September 2017

R Bruskewitz

7

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20 September 2017

W M Stadler

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20 September 2017

L F Meisner

9

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20 September 2017

K W Gilchrist

10

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20 September 2017

M A Newton

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20 September 2017

F M Waldman

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20 September 2017

C A Reznikoff

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20 September 2017

1 January 1998

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20 September 2017

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20 September 2017

12

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20 September 2017

163-174

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20 September 2017

2

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describes a project that uses

20 September 2017

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hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316442

Overexpression of cyclin D1 correlates with early recurrence in superficial bladder cancers

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316442

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316442

20q gain associates with immortalization: 20q13.2 amplification correlates with genome instability in human papillomavirus 16 E7 transformed human uroepithelial cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316442

Therapy of superficial bladder cancer.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316442

A molecular genetic model of human bladder cancer pathogenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316442

Pathology and staging of bladder cancer.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316442

Bladder cancer epidemiology and pathogenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316442

A molecular and epidemiological study on bladder cancer: p53 mutations, tobacco smoking, and occupational exposure to asbestos

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316442

Elevated p16 at senescence and loss of p16 at immortalization in human papillomavirus 16 E6, but not E7, transformed human uroepithelial cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316442

Two molecular pathways to transitional cell carcinoma of the bladder.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316442

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316442

A cell cycle regulator potentially involved in genesis of many tumor types

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316442

Assessing the significance of chromosome-loss data: where are suppressor genes for bladder cancer?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316442

Long-term genome stability and minimal genotypic and phenotypic alterations in HPV16 E7-, but not E6-, immortalized human uroepithelial cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316442

Growth suppression by p16ink4 requires functional retinoblastoma protein

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316442

Molecular and cell biology of replicative senescence

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316442

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316442

Altered growth patterns in vitro of human papillary transitional carcinoma cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316442

The Longevity of Cultured Human Cells*

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316442

Growth kinetics and differentiation in vitro of normal human uroepithelial cells on collagen gel substrates in defined medium

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316442

p53 mutations in human cancers

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316442

5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316442

Overexpressed cyclin D1 protein related to p53 and retinoblastoma proteins in transitional cell carcinoma of the urinary tract.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316442

Frequent homozygous deletion of cyclin-dependent kinase inhibitor 2 (MTS1, p16) in superficial bladder cancer detected by fluorescence in situ hybridization.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316442

Accumulation of nuclear p53 and tumor progression in bladder cancer.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316442

Nuclear overexpression of p53 protein in transitional cell bladder carcinoma: a marker for disease progression

26 November 2018

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12 December 2020

Increased p16 levels correlate with pRb alterations in human urothelial cells

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12 December 2020

Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

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12 December 2020

Amplification, increased dosage and in situ expression of the telomerase RNA gene in human cancer

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12 December 2020

Chromosomal imbalance maps of malignant solid tumors: a cytogenetic survey of 3185 neoplasms

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12 December 2020

Infrequent somatic alteration of p16/MTS1 in human primary superficial bladder cancers

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12 December 2020

Methylation of the 5' CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing

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12 December 2020

Frequency of homozygous deletion at p16/CDKN2 in primary human tumours

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12 December 2020

Cooperative effects of p53 and pRB alterations in primary superficial bladder tumors

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12 December 2020

Rates of p16 (MTS1) mutations in primary tumors with 9p loss

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12 December 2020

P16 gene in uncultured tumours

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12 December 2020

Accumulated allelic losses in the development of invasive urothelial cancer

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12 December 2020

Loss of RB protein expression in primary bladder cancer correlates with loss of heterozygosity at the RB locus and tumor progression

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12 December 2020

Allelotype of human bladder cancer

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12 December 2020

Molecular genetic alterations in superficial and locally advanced human bladder cancer

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12 December 2020

Deletion mapping implicates two tumor suppressor genes on chromosome 8p in the development of bladder cancer

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12 December 2020

Identification of gains and losses of DNA sequences in primary bladder cancer by comparative genomic hybridization

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12 December 2020

Identifiers

DOI

10.1101/GAD.12.2.163

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20 September 2017

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20 September 2017

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