(Q30475165)

English

Helicobacter pylori cytotoxin-associated gene A (CagA) subverts the apoptosis-stimulating protein of p53 (ASPP2) tumor suppressor pathway of the host

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scholarly article

1 reference

Europe PubMed Central

16 October 2017

Helicobacter pylori cytotoxin-associated gene A (CagA) subverts the apoptosis-stimulating protein of p53 (ASPP2) tumor suppressor pathway of the host (English)

1 reference

Europe PubMed Central

16 October 2017

Helicobacter pylori

0 references

Helicobacter pylori infectious disease

1 reference

based on heuristic

inferred from title

apoptotic process

1 reference

based on heuristic

inferred from title

4

object named as

Rino Rappuoli

1 reference

Europe PubMed Central

16 October 2017

6

object named as

Hidde L Ploegh

1 reference

Europe PubMed Central

16 October 2017

2

object named as

Eric Spooner

1 reference

Europe PubMed Central

16 October 2017

Annemarthe G van der Veen

3

object named as

Annemarthe G Van der Veen

1 reference

Europe PubMed Central

16 October 2017

1

object named as

Ludovico Buti

1 reference

Europe PubMed Central

16 October 2017

author name string

Antonello Covacci

5

1 reference

Europe PubMed Central

16 October 2017

language of work or name

0 references

publication date

11 May 2011

1 reference

Europe PubMed Central

16 October 2017

number of pages

6

1 reference

based on heuristic

inferred from page(s)

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

16 October 2017

108

1 reference

Europe PubMed Central

16 October 2017

9238-9243

1 reference

Europe PubMed Central

16 October 2017

22

1 reference

Europe PubMed Central

16 October 2017

Cytoplasmic ASPP1 inhibits apoptosis through the control of YAP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

Helicobacter pylori CagA targets gastric tumor suppressor RUNX3 for proteasome-mediated degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

ASPP2 binds Par-3 and controls the polarity and proliferation of neural progenitors during CNS development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

ASPP2 regulates epithelial cell polarity through the PAR complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

Regulation of p53 tumor suppressor by Helicobacter pylori in gastric epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

The dASPP-dRASSF8 complex regulates cell-cell adhesion during Drosophila retinal morphogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

Helicobacter pylori usurps cell polarity to turn the cell surface into a replicative niche

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

The DEAD box protein Ddx42p modulates the function of ASPP2, a stimulator of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

p53 target DDA3 binds ASPP2 and inhibits its stimulation on p53-mediated BAX activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

A transgenic Drosophila model demonstrates that the Helicobacter pylori CagA protein functions as a eukaryotic Gab adaptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

Regulation of gastric carcinogenesis by Helicobacter pylori virulence factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

Helicobacter pylori dampens gut epithelial self-renewal by inhibiting apoptosis, a bacterial strategy to enhance colonization of the stomach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

Helicobacter pylori CagA interacts with E-cadherin and deregulates the beta-catenin signal that promotes intestinal transdifferentiation in gastric epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

Phosphorylation of Helicobacter pylori CagA by c-Abl leads to cell motility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

Interaction of CagA with Crk plays an important role in Helicobacter pylori-induced loss of gastric epithelial cell adhesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

Helicobacter pylori CagA induces a transition from polarized to invasive phenotypes in MDCK cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

Activation of beta-catenin by carcinogenic Helicobacter pylori

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

Helicobacter pylori CagA protein targets the c-Met receptor and enhances the motogenic response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

Attenuation of Helicobacter pylori CagA x SHP-2 signaling by interaction between CagA and C-terminal Src kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

Grb2 is a key mediator of helicobacter pylori CagA protein activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

c-Src/Lyn kinases activate Helicobacter pylori CagA through tyrosine phosphorylation of the EPIYA motifs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

ASPP proteins specifically stimulate the apoptotic function of p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

Yes-associated protein and p53-binding protein-2 interact through their WW and SH3 domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

Translocation of Helicobacter pylori CagA into gastric epithelial cells by type IV secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

Helicobacter pylori CagA protein can be tyrosine phosphorylated in gastric epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

Tyrosine phosphorylation of the Helicobacter pylori CagA antigen after cag-driven host cell translocation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

APCL, a central nervous system-specific homologue of adenomatous polyposis coli tumor suppressor, binds to p53-binding protein 2 and translocates it to the perinucleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

NF-kappaB subunit p65 binds to 53BP2 and inhibits cell death induced by 53BP2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

Protein phosphatase 1 interacts with p53BP2, a protein which binds to the tumour suppressor p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

Bcl2 inhibits apoptosis associated with terminal differentiation of HL-60 myeloid leukemia cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

SV40 large tumor antigen can regulate some cellular transcripts in a positive fashion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

Association of human papillomavirus types 16 and 18 E6 proteins with p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107298

20 June 2018

Drosophila ASPP regulates C-terminal Src kinase activity.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1106200108

21 January 2018

Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.1106200108

1 reference

Europe PubMed Central

16 October 2017

2011PNAS..108.9238B

0 references

1 reference

Europe PubMed Central

16 October 2017

1 reference

Europe PubMed Central

16 October 2017

ResearchGate publication ID

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