(Q30656324)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11453305%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

Comparison of cancer risk estimates for vinyl chloride using animal and human data with a PBPK model (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11453305%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

5

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9 November 2019

author name string

H J Clewell

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11453305%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

P R Gentry

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11453305%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

J M Gearhart

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11453305%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

B C Allen

4

1 reference

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9 November 2019

publication date

1 July 2001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11453305%20AND%20SRC:MED&resulttype=core&format=json

Science of the Total Environment

9 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11453305%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

volume

274

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11453305%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

page(s)

37-66

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11453305%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

issue

1-3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11453305%20AND%20SRC:MED&resulttype=core&format=json

Physiologically based pharmacokinetics and the risk assessment process for methylene chloride.

9 November 2019

cites work

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7 January 2021

Quantitative evaluation of the metabolic interactions between trichloroethylene and 1,1-dichloroethylene in vivo using gas uptake methods.

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7 January 2021

Monitoring Exposures to Vinyl Chloride Vapor: Breath Analysis and Continuous Air Sampling

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7 January 2021

Chloroethylene mixtures: pharmacokinetic modeling and in vitro metabolism of vinyl chloride, trichloroethylene, and trans-1,2-dichloroethylene in rat.

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7 January 2021

Mutagenic and carcinogenic effects of vinyl chloride

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7 January 2021

Human, rat and mouse liver-mediated mutagenicity of vinyl chloride inS. typhimurium strains

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7 January 2021

Pharmacokinetics of vinyl chloride

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7 January 2021

Disposition of (1,2-14C) vinyl chloride in the rat

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7 January 2021

Pharmacokinetics of vinyl chloride in the rat

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7 January 2021

Pharmacokinetics of vinyl chloride in the Rhesus monkey

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7 January 2021

Enhancement of the hepatotoxicity of chloroform in B6C3F1 mice by corn oil: implications for chloroform carcinogenesis

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7 January 2021

Mortality and cancer morbidity in a group of Swedish VCM and PCV production workers

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7 January 2021

Incorporation of biological information in cancer risk assessment: example--vinyl chloride

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7 January 2021

The vinyl chloride DNA derivative N2,3-ethenoguanine produces G----A transitions in Escherichia coli

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7 January 2021

Incorporation of pharmacokinetics in noncancer risk assessment: example with chloropentafluorobenzene

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7 January 2021

Species and strain sensitivity to the induction of peroxisome proliferation by chloroacetic acids

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7 January 2021

All four known cyclic adducts formed in DNA by the vinyl chloride metabolite chloroacetaldehyde are released by a human DNA glycosylase

1 reference

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7 January 2021

The effect of age and exposure duration on cancer induction by a known carcinogen in rats, mice, and hamsters.

1 reference

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7 January 2021

Physiologically based pharmacokinetic model for vinylidene chloride.

1 reference

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7 January 2021

Vinyl chloride-induced DNA adducts. II: Formation and persistence of 7-(2'-oxoethyl)guanine and N2,3-ethenoguanine in rat tissue DNA.

1 reference

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7 January 2021

Lifespan oral toxicity study of vinyl chloride in rats

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7 January 2021

Pharmacokinetics of halogenated ethylenes in rats

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7 January 2021

Metabolism of inhaled brominated hydrocarbons: validation of gas uptake results by determination of a stable metabolite.

1 reference

https://api.crossref.org/works/10.1016%2FS0048-9697%2801%2900730-6

7 January 2021

Partition coefficients of low-molecular-weight volatile chemicals in various liquids and tissues.

1 reference

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7 January 2021

Gas Uptake Inhalation Techniques and the Rates of Metabolism of Chloromethanes, Chloroethanes, and Chloroethylenes in the Rat

1 reference

https://api.crossref.org/works/10.1016%2FS0048-9697%2801%2900730-6

7 January 2021

Variability of physiologically based pharmacokinetic (PBPK) model parameters and their effects on PBPK model predictions in a risk assessment for perchloroethylene (PCE)

1 reference

https://api.crossref.org/works/10.1016%2FS0048-9697%2801%2900730-6

7 January 2021

Resolution of dose-response toxicity data for chemicals requiring metabolic activation: Example?Vinyl chloride*1

1 reference

https://api.crossref.org/works/10.1016%2FS0048-9697%2801%2900730-6

7 January 2021

The biological fate in rats of vinyl chloride in relation to its oncogenicity

1 reference

https://api.crossref.org/works/10.1016%2FS0048-9697%2801%2900730-6

7 January 2021

Metabolism of [14C]- and [36Cl]-labeled vinyl chloride in vivo and in vitro

1 reference

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7 January 2021

Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects

1 reference

https://api.crossref.org/works/10.1016%2FS0048-9697%2801%2900730-6

7 January 2021

Oncogenic and mutagenic risks in communities with polyvinyl chloride production facilities

1 reference

https://api.crossref.org/works/10.1016%2FS0048-9697%2801%2900730-6

7 January 2021

The interaction of vinyl chloride with rat hepatic microsomal cytochrome P-450 in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0048-9697%2801%2900730-6

7 January 2021

Chemical modification of acute hepatotoxicity of vinyl chloride monomer in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0048-9697%2801%2900730-6

7 January 2021

Influence of exposure mode on vinyl chloride action

1 reference

https://api.crossref.org/works/10.1016%2FS0048-9697%2801%2900730-6

7 January 2021

A mortality study of vinyl chloride monomer workers employed in the United Kingdom in 1940-1974

1 reference

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7 January 2021

Increased alkylation of liver DNA and cell turnover in young versus old rats exposed to vinyl chloride correlates with cancer susceptibility.

1 reference

https://api.crossref.org/works/10.1016%2FS0048-9697%2801%2900730-6

7 January 2021

Mutagenicity of vinyl chloride, chloroethyleneoxide, chloroacetaldehyde and chloroethanol

1 reference

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7 January 2021

Carcinogenicity of vinyl chloride in Sprague-Dawley rats after prenatal and postnatal exposure.

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7 January 2021

Carcinogenicity bioassays of vinyl chloride monomer: a model of risk assessment on an experimental basis

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7 January 2021

Proportional mortality among vinyl-chloride workers

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7 January 2021

Cytochrome P450-related differences between rats and mice in the metabolism of benzene, toluene and trichloroethylene in liver microsomes

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7 January 2021

Effect of exposure route on potency of carcinogens.

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7 January 2021

Formation and inactivation of a chemically reactive metabolite of vinyl chloride

1 reference

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7 January 2021

Mortality from liver disease among Italian vinyl chloride monomer/polyvinyl chloride manufacturers.

1 reference

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7 January 2021

A physiologically based description of the inhalation pharmacokinetics of styrene in rats and humans.

1 reference

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7 January 2021

Predicting Cancer Risk from Vinyl Chloride Exposure with a Physiologically Based Pharmacokinetic Model

1 reference

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7 January 2021

In vitro metabolism of methylene chloride in human and animal tissues: use in physiologically based pharmacokinetic models

1 reference

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7 January 2021

Study of mortality among chemical workers in the Kanawha Valley of West Virginia

1 reference

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7 January 2021

In vivo formation and persistence of modified nucleosides resulting from alkylating agents

1 reference

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7 January 2021

The vinyl chloride-derived nucleoside, N2,3-ethenoguanosine, is a highly efficient mutagen in transcription.

1 reference

https://api.crossref.org/works/10.1016%2FS0048-9697%2801%2900730-6

7 January 2021

Etheno adducts formed in DNA of vinyl chloride-exposed rats are highly persistent in liver

1 reference

https://api.crossref.org/works/10.1016%2FS0048-9697%2801%2900730-6

7 January 2021

Mortality surveillance in a large chemical company: the Union Carbide Corporation experience, 1974-1983.

1 reference

https://api.crossref.org/works/10.1016%2FS0048-9697%2801%2900730-6

7 January 2021

Dose-dependent fate of vinyl chloride and its possible relationship to oncogenicity in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0048-9697%2801%2900730-6

7 January 2021

Fate of [14C]vinyl chloride after single oral administration in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0048-9697%2801%2900730-6

7 January 2021

Vinyl chloride-induced depression of hepatic non-protein sulfhydryl content and effects on bromosulphalein (BSP) clearance in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0048-9697%2801%2900730-6

7 January 2021

Hepatic macromolecular binding following exposure to vinyl chloride

1 reference

https://api.crossref.org/works/10.1016%2FS0048-9697%2801%2900730-6

7 January 2021

Neoplastic risk among workers exposed to vinyl chloride

1 reference

https://api.crossref.org/works/10.1016%2FS0048-9697%2801%2900730-6

7 January 2021

German investigations on morbidity and mortality of workers exposed to vinyl chloride

1 reference

https://api.crossref.org/works/10.1016%2FS0048-9697%2801%2900730-6

7 January 2021

Pharmacodynamics and uptake of vinyl chloride monomer administered by various routes to rats

1 reference

https://api.crossref.org/works/10.1016%2FS0048-9697%2801%2900730-6

7 January 2021

Cohort and case-control analyses of workers exposed to vinyl chloride: an update

1 reference

https://api.crossref.org/works/10.1016%2FS0048-9697%2801%2900730-6

7 January 2021

A collaborative study of cancer incidence and mortality among vinyl chloride workers

1 reference

https://api.crossref.org/works/10.1016%2FS0048-9697%2801%2900730-6

7 January 2021

10.1016/S0048-9697(01)00730-6

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11453305%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference