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DNA methylation in health and disease
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
11262868
retrieved
26 June 2017
review article
1 reference
stated in
Europe PubMed Central
title
DNA methylation in health and disease
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
11262868
retrieved
26 June 2017
main subject
DNA methylation
0 references
author name string
Robertson KD
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11262868
retrieved
26 June 2017
Wolffe AP
series ordinal
2
1 reference
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Europe PubMed Central
PubMed ID
11262868
retrieved
26 June 2017
publication date
1 October 2000
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Europe PubMed Central
PubMed ID
11262868
retrieved
26 June 2017
published in
Nature Reviews Genetics
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stated in
Europe PubMed Central
PubMed ID
11262868
retrieved
26 June 2017
volume
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11262868
retrieved
26 June 2017
page(s)
11-19
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Europe PubMed Central
PubMed ID
11262868
retrieved
26 June 2017
issue
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11262868
retrieved
26 June 2017
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Number of CpG islands and genes in human and mouse
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5-Methylcytosine as an Endogenous Mutagen in the Human LDL Receptor and p53 Genes
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Baculovirus-mediated expression and characterization of the full-length murine DNA methyltransferase
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The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors
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A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei
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Human DNA-(Cytosine-5) Methyltransferase-PCNA Complex as a Target for p21WAF1
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Role for DNA methylation in genomic imprinting
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Loss of methylation activates Xist in somatic but not in embryonic cells
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Drosophila proteins related to vertebrate DNA (5-cytosine) methyltransferases
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Vestiges of a DNA methylation system in Drosophila melanogaster?
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Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases
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Conserved plant genes with similarity to mammalian de novo DNA methyltransferases.
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Mammalian (cytosine-5) methyltransferases cause genomic DNA methylation and lethality in Drosophila.
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De novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5-)-methyltransferase
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CpG methylation is maintained in human cancer cells lacking DNMT1.
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DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters
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DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci
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Crossref
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Cytosine methylation and the ecology of intragenomic parasites
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7 January 2021
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Eukaryotic DNA methylation as an evolutionary device
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Identification of a 3 kb Alu-mediated BRCA1 gene rearrangement in two breast/ovarian cancer families
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The impact of L1 retrotransposons on the human genome
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Transcriptional silencing of human Alu sequences and inhibition of protein binding in the box B regulatory elements by 5'-CG-3' methylation
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7 January 2021
based on heuristic
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DNA hypomethylation leads to elevated mutation rates
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7 January 2021
based on heuristic
inferred from DOI database lookup
Transcription of IAP endogenous retroviruses is constrained by cytosine methylation
1 reference
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7 January 2021
based on heuristic
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Undermethylation associated with retroelement activation and chromosome remodelling in an interspecific mammalian hybrid
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2F35049533
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7 January 2021
based on heuristic
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DNA methylation and expression of LINE-1 and HERV-K provirus sequences in urothelial and renal cell carcinomas
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
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7 January 2021
based on heuristic
inferred from DOI database lookup
Metastatic rat carcinoma cells express a new retrotransposon
1 reference
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Crossref
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7 January 2021
based on heuristic
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A sex chromosome rearrangement in a human XX male caused by Alu-Alu recombination
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2F35049533
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7 January 2021
based on heuristic
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Emerin deletion reveals a common X-chromosome inversion mediated by inverted repeats.
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2F35049533
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7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of crossing-over by DNA methylation in Ascobolus
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2F35049533
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7 January 2021
based on heuristic
inferred from DOI database lookup
Imprinted chromosomal regions of the human genome display sex-specific meiotic recombination frequencies.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abnormal methylation pattern in constitutive and facultative (X inactive chromosome) heterochromatin of ICF patients
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
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7 January 2021
based on heuristic
inferred from DOI database lookup
DNA demethylation and pericentromeric rearrangements of chromosome 1.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
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7 January 2021
based on heuristic
inferred from DOI database lookup
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of DNA methylation on DNA-binding proteins and gene expression.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
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7 January 2021
based on heuristic
inferred from DOI database lookup
The solution structure of the domain from MeCP2 that binds to methylated DNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MeCP2 driven transcriptional repression in vitro: selectivity for methylated DNA, action at a distance and contacts with the basal transcription machinery
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA methylation specifies chromosomal localization of MeCP2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The methyl-CpG binding transcriptional repressor MeCP2 stably associates with nucleosomal DNA
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chromatin structure is required to block transcription of the methylated herpes simplex virus thymidine kinase gene
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
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7 January 2021
based on heuristic
inferred from DOI database lookup
DNA methylation directs a time-dependent repression of transcription initiation.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of higher-order folding by core histone acetylation dramatically enhances transcription of nucleosomal arrays by RNA polymerase III
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Active repression of methylated genes by the chromosomal protein MBD1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methylation-mediated transcriptional silencing in euchromatin by methyl-CpG binding protein MBD1 isoforms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA methyltransferase Dnmt1 associates with histone deacetylase activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Maintenance of genomic methylation requires a SWI2/SNF2-like protein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of DNA methyltransferase gene in mature and immature neurons as well as proliferating cells in mice.
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA methyltransferase contributes to delayed ischemic brain injury.
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Variability of clinical and immunological phenotype in immunodeficiency-centromeric instability-facial anomalies syndrome. Report of two new patients and review of the literature
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https://api.crossref.org/works/10.1038%2F35049533
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7 January 2021
based on heuristic
inferred from DOI database lookup
An embryonic-like methylation pattern of classical satellite DNA is observed in ICF syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
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7 January 2021
based on heuristic
inferred from DOI database lookup
Whole-genome methylation scan in ICF syndrome: hypomethylation of non-satellite DNA repeats D4Z4 and NBL2.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
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7 January 2021
based on heuristic
inferred from DOI database lookup
Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
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7 January 2021
based on heuristic
inferred from DOI database lookup
The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning, expression and chromosome locations of the human DNMT3 gene family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Localization of the ICF syndrome to chromosome 20 by homozygosity mapping
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A progressive syndrome of autism, dementia, ataxia, and loss of purposeful hand use in girls: Rett's syndrome: report of 35 cases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
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7 January 2021
based on heuristic
inferred from DOI database lookup
Rett syndrome and beyond: recurrent spontaneous and familial MECP2 mutations at CpG hotspots
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of Rett syndrome mutations of the methyl-CpG binding domain of the transcriptional repressor MeCP2 on selectivity for association with methylated DNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The methyl-CpG binding protein MeCP2 is essential for embryonic development in the mouse.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Breaking the silence in Rett syndrome
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional noise and the evolution of gene number
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Trinucleotide repeat expansions in neurological disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mapping of DNA instability at the fragile X to a trinucleotide repeat sequence p(CCG)n
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Instability of a 550-base pair DNA segment and abnormal methylation in fragile X syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Variation of the CGG repeat at the fragile X site results in genetic instability: Resolution of the Sherman paradox
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2F35049533
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7 January 2021
based on heuristic
inferred from DOI database lookup
Hypermethylation of telomere-like foldbacks at codon 12 of the human c-Ha-ras gene and the trinucleotide repeat of the FMR-1 gene of fragile X.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification and characterization of a family of mammalian methyl-CpG binding proteins
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High resolution methylation analysis of the FMR1 gene trinucleotide repeat region in fragile X syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35049533
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/35049533
1 reference
stated in
Europe PubMed Central
PubMed ID
11262868
retrieved
26 June 2017
Dimensions Publication ID
1048797914
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PubMed ID
11262868
1 reference
stated in
Europe PubMed Central
PubMed ID
11262868
retrieved
26 June 2017
ResearchGate publication ID
12069717
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Springer Nature article ID
10.1038/35049533
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