(Q30785663)

English

Impact of Nonspecific Binding to Microsomes and Phospholipid on the Inhibition of Cytochrome P4502D6: Implications for Relating in Vitro Inhibition Data to in Vivo Drug Interactions

scientific article published on May 1, 2003

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scholarly article

1 reference

Europe PubMed Central

26 June 2017

Impact of nonspecific binding to microsomes and phospholipid on the inhibition of cytochrome P4502D6: implications for relating in vitro inhibition data to in vivo drug interactions (English)

1 reference

Europe PubMed Central

26 June 2017

Impact of Nonspecific Binding to Microsomes and Phospholipid on the Inhibition of Cytochrome P4502D6: Implications for Relating in Vitro Inhibition Data to in Vivo Drug Interactions (English)

1 reference

10.1124/DMD.31.5.606

https://api.crossref.org/works/10.1124/DMD.31.5.606

24 December 2023

cytochrome P-450 CYP2D6 inhibitors

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12695349

24 December 2023

pharmaceutical science

1 reference

10.1124/DMD.31.5.606

https://api.crossref.org/works/10.1124/DMD.31.5.606

24 December 2023

1 reference

10.1124/DMD.31.5.606

https://api.crossref.org/works/10.1124/DMD.31.5.606

24 December 2023

author name string

Jeannine M. Margolis

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12695349

24 December 2023

R. Scott Obach

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12695349

24 December 2023

language of work or name

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12695349

24 December 2023

publication date

1 May 2003

1 reference

Europe PubMed Central

26 June 2017

full work available at URL

https://syndication.highwire.org/content/doi/10.1124/dmd.31.5.606

1 reference

10.1124/DMD.31.5.606

https://api.crossref.org/works/10.1124/DMD.31.5.606

24 December 2023

Drug Metabolism and Disposition

1 reference

Europe PubMed Central

26 June 2017

31

1 reference

Europe PubMed Central

26 June 2017

606-611

1 reference

Europe PubMed Central

26 June 2017

5

1 reference

Europe PubMed Central

26 June 2017

The use of in vitro methods to predict in vivo pharmacokinetics and drug interactions

1

1 reference

10.1124/DMD.31.5.606

https://api.crossref.org/works/10.1124/DMD.31.5.606

24 December 2023

Binding of basic and acidic drugs to rat tissue subcellular fractions

2

1 reference

10.1124/DMD.31.5.606

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24 December 2023

Membrane lipids as intracellular binders of chlorpromazine and related drugs

4

1 reference

10.1124/DMD.31.5.606

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24 December 2023

ENZYME-STRUCTURE RELATIONSHIPS IN THE ENDOPLASMIC RETICULUM OF RAT LIVER : A Morphological and Biochemical Study

5

1 reference

10.1124/DMD.31.5.606

https://api.crossref.org/works/10.1124/DMD.31.5.606

24 December 2023

Influence of microsomal concentration on apparent intrinsic clearance: implications for scaling in vitro data.

7

1 reference

10.1124/DMD.31.5.606

https://api.crossref.org/works/10.1124/DMD.31.5.606

24 December 2023

Development of a high throughput equilibrium dialysis method

8

1 reference

10.1124/DMD.31.5.606

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24 December 2023

Sense and nonsense in the prediction of drug-drug interactions

10

1 reference

10.1124/DMD.31.5.606

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24 December 2023

Nonspecific binding of drugs to human liver microsomes

11

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24 December 2023

Drug interactions with cisapride: clinical implications

12

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24 December 2023

Prediction of human clearance of twenty-nine drugs from hepatic microsomal intrinsic clearance data: An examination of in vitro half-life approach and nonspecific binding to microsomes.

14

1 reference

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24 December 2023

Effects of the antifungal agents on oxidative drug metabolism: clinical relevance

16

1 reference

10.1124/DMD.31.5.606

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24 December 2023

Human drug metabolism and the cytochromes P450: application and relevance of in vitro models

17

1 reference

10.1124/DMD.31.5.606

https://api.crossref.org/works/10.1124/DMD.31.5.606

24 December 2023

Microsomal binding of amitriptyline: effect on estimation of enzyme kinetic parameters in vitro.

18

1 reference

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Phosphatidylserine as a determinant for the tissue distribution of weakly basic drugs in rats.

20

1 reference

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24 December 2023

Identifiers

10.1124/DMD.31.5.606

1 reference

Europe PubMed Central

26 June 2017

1 reference

Europe PubMed Central

26 June 2017

ResearchGate publication ID

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