(Q31008848)

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Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits

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scholarly article

1 reference

Europe PubMed Central

28 June 2017

Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits (English)

1 reference

Europe PubMed Central

28 June 2017

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Aldons Jake Lusis

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object named as

Aldons J Lusis

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Europe PubMed Central

28 June 2017

Margarete Mehrabian

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object named as

Margarete Mehrabian

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Europe PubMed Central

28 June 2017

12

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Eric E Schadt

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28 June 2017

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Pek Yee Lum

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28 June 2017

Lawrence W Castellani

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object named as

Lawrence W Castellani

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2

object named as

Hooman Allayee

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author name string

Jirina Stockton

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28 June 2017

Thomas A Drake

5

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28 June 2017

Michael Suh

7

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Christopher Armour

8

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28 June 2017

Stephen Edwards

9

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28 June 2017

John Lamb

10

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28 June 2017

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2 October 2005

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28 June 2017

Nature Genetics

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28 June 2017

37

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28 June 2017

1224-1233

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28 June 2017

11

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28 June 2017

Development of insulin resistance and obesity in mice overexpressing cellular glutathione peroxidase

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In silico mapping of complex disease-related traits in mice.

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Genetic analysis of the mouse brain proteome.

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In silico genetics: identification of a functional element regulating H2-Ealpha gene expression

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Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease.

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The transcriptional program of sporulation in budding yeast

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Cluster analysis and display of genome-wide expression patterns

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Functional discovery via a compendium of expression profiles

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PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

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Functional genomics identifies monopolin: a kinetochore protein required for segregation of homologs during meiosis i.

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Genetic loci determining bone density in mice with diet-induced atherosclerosis

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Genetics of atherosclerosis: the search for genes acting at the level of the vessel wall

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Experimental strategies for the genetic dissection of complex traits in animal models

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The Ensembl genome database project

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A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome.

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Initial sequencing and comparative analysis of the mouse genome

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Cis-acting expression quantitative trait loci in mice

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Regulation of bone mass in mice by the lipoxygenase gene Alox15

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An integrative genomics approach to infer causal associations between gene expression and disease

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Identification of 5-lipoxygenase as a major gene contributing to atherosclerosis susceptibility in mice

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Amino acid differences in the deduced 5-lipoxygenase sequence of CAST atherosclerosis-resistance mice confer impaired activity when introduced into the human ortholog.

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5-Lipoxygenase and atherosclerosis

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Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression

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An integrative genomics approach to the reconstruction of gene networks in segregating populations.

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Osteopontin-deficient mice are resistant to ovariectomy-induced bone resorption

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Obesity and hyperleptinemia in metallothionein (-I and -II) null mice

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Fat's loss is bone's gain

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Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

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The functional landscape of mouse gene expression

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Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer

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Microarray standard data set and figures of merit for comparing data processing methods and experiment designs

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Europe PubMed Central

28 June 2017

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1 reference

Europe PubMed Central

28 June 2017

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