(Q31814817)

4 July 2017

Ligand-dependent activation of EphA4 signaling regulates the proteolysis of amyloid precursor protein through a Lyn-mediated pathway (English)

1 reference

4 July 2017

1 reference

1 reference

Presenilin 1

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Ephrin A1

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LYN proto-oncogene, Src family tyrosine kinase

1 reference

Ephrin A3

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protein tyrosine kinase binding

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Wen-Ming Hsu

4

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author name string

Wei-Bin Lai

1

1 reference

4 July 2017

Bo-Jeng Wang

2

1 reference

4 July 2017

Ming-Kuan Hu

3

1 reference

4 July 2017

Guor Mour Her

5

1 reference

4 July 2017

Yung-Feng Liao

6

1 reference

4 July 2017

12 November 2013

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4 July 2017

Molecular Neurobiology

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4 July 2017

49

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4 July 2017

1055-1068

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4 July 2017

2

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https://scigraph.springernature.com/pub.10.1007/s12035-013-8580-x

4 July 2017

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cites work

Neurofibrillary tangles and Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Senile plaque neurites in Alzheimer disease accumulate amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Effects of dasatinib on EphA2 receptor tyrosine kinase activity and downstream signalling in pancreatic cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

β- but not γ-secretase proteolysis of APP causes synaptic and memory deficits in a mouse model of dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Inhibition of γ-secretase worsens memory deficits in a genetically congruous mouse model of Danish dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

The Eph family of receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Localization of EphA4 in axon terminals and dendritic spines of adult rat hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Eph receptors and neural plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Eph-ephrin bidirectional signaling in physiology and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Ephrin-B reverse signaling promotes structural and functional synaptic maturation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Ephrin-B1 and ephrin-B2 mediate EphB-dependent presynaptic development via syntenin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

EphrinA6 on chick retinal axons is a key component for p75(NTR)-dependent axon repulsion and TrkB-dependent axon branching

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Synaptic activity prompts gamma-secretase-mediated cleavage of EphA4 and dendritic spine formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Eph receptors and ephrins in neural development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Multiple roles of EPH receptors and ephrins in neural development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

EphA4 receptor tyrosine kinase is a modulator of onset and disease severity of experimental autoimmune encephalomyelitis (EAE)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Rac1 changes the substrate specificity of gamma-secretase between amyloid precursor protein and Notch1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

The Lyn kinase C-lobe mediates Golgi export of Lyn through conformation-dependent ACSL3 association

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Interactions between Eph kinases and ephrins provide a mechanism to support platelet aggregation once cell-to-cell contact has occurred

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Tumor necrosis factor-alpha, interleukin-1beta, and interferon-gamma stimulate gamma-secretase-mediated cleavage of amyloid precursor protein through a JNK-dependent MAPK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Comparison of transfection conditions for a lentivirus vector produced in large volumes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Phosphorylation of tyrosine residues in the kinase domain and juxtamembrane region regulates the biological and catalytic activities of Eph receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Statins reduce amyloid-beta production through inhibition of protein isoprenylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

The C-terminal fragment of the Alzheimer's disease amyloid protein precursor is degraded by a proteasome-dependent mechanism distinct from gamma-secretase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Differential effects between γ-secretase inhibitors and modulators on cognitive function in amyloid precursor protein-transgenic and nontransgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

The amyloid precursor protein intracellular domain (AICD) as modulator of gene expression, apoptosis, and cytoskeletal dynamics-relevance for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

The gamma secretase-generated carboxyl-terminal domain of the amyloid precursor protein induces apoptosis via Tip60 in H4 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Nuclear signalling by membrane protein intracellular domains: the AICD enigma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Kinase-dependent and kinase-independent functions of EphA4 receptors in major axon tract formation in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Recruitment of Eph receptors into signaling clusters does not require ephrin contact

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Eph/ephrin molecules--a hub for signaling and endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

The Rab5 guanylate exchange factor Rin1 regulates endocytosis of the EphA4 receptor in mature excitatory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Inhibition of Src kinase activity attenuates amyloid associated microgliosis in a murine model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Effects of tumor necrosis factor-alpha (TNF alpha) in epidermal keratinocytes revealed using global transcriptional profiling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Pathway-specific profiling identifies the NF-kappa B-dependent tumor necrosis factor alpha-regulated genes in epidermal keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Cytokine, chemokine and growth factor gene profiling of cultured human astrocytes after exposure to proinflammatory stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Specific and shared targets of ephrin A signaling in epidermal keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

FBL2 regulates amyloid precursor protein (APP) metabolism by promoting ubiquitination-dependent APP degradation and inhibition of APP endocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

APCCdh1 mediates EphA4-dependent downregulation of AMPA receptors in homeostatic plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8580-X

Early changes in hippocampal Eph receptors precede the onset of memory decline in mouse models of Alzheimer's disease.

21 January 2018

1 reference

12 December 2020

Generation of an apoptotic intracellular peptide by gamma-secretase cleavage of Alzheimer's amyloid beta protein precursor.

1 reference

12 December 2020

Dendritic spine loss and synaptic alterations in Alzheimer's disease.

1 reference

12 December 2020

Identification of microglial signal transduction pathways mediating a neurotoxic response to amyloidogenic fragments of beta-amyloid and prion proteins

1 reference

12 December 2020

Evidence that the amyloid-β protein precursor intracellular domain, AICD, derives from β-secretase-generated C-terminal fragment

1 reference

12 December 2020

Neurotoxicity of a carboxyl-terminal fragment of the Alzheimer's amyloid precursor protein.

1 reference

12 December 2020

Amyloid fibrils activate tyrosine kinase-dependent signaling and superoxide production in microglia.

1 reference

12 December 2020

10.1007/S12035-013-8580-X

Identifiers

DOI

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Dimensions Publication ID

4 July 2017

1052023614

0 references

Fatcat ID

release_u7yftsm43jhwza26duclr7vobq

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/u7yftsm43jhwza26duclr7vobq

24 November 2022

mapped directly with Wikidata item

1 reference