(Q32056121)

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Sequence variations in the Plasmodium vivax dihydrofolate reductase-thymidylate synthase gene and their relationship with pyrimethamine resistance

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Europe PubMed Central

PubMed publication ID

6 July 2017

Sequence variations in the Plasmodium vivax dihydrofolate reductase-thymidylate synthase gene and their relationship with pyrimethamine resistance (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

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Plasmodium vivax

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author name string

de Pécoulas PE

1

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

Tahar R

2

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

Ouatas T

3

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

Mazabraud A

4

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

Basco LK

5

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

language of work or name

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inferred from title

publication date

1 May 1998

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

Molecular and Biochemical Parasitology

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Europe PubMed Central

PubMed publication ID

6 July 2017

92

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Europe PubMed Central

PubMed publication ID

6 July 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

265-273

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

The dynamics of drug resistance in Plasmodium falciparum

1 reference

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Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum

1 reference

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Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria

1 reference

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Point mutations in the dihydrofolate reductase-thymidylate synthase gene as the molecular basis for pyrimethamine resistance in Plasmodium falciparum

1 reference

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Chromosomal rearrangements and point mutations in the DHFR-TS gene of Plasmodium chabaudi under antifolate selection

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The dihydrofolate reductase-thymidylate synthetase gene in the drug resistance of malaria parasites

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Mechanisms of pyrimethamine resistance in two different strains of Plasmodium berghei.

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Point mutations in the dihydrofolate reductase-thymidylate synthase gene and pyrimethamine and cycloguanil resistance in Plasmodium falciparum

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Association between antifol resistance in vitro and DHFR gene point mutation in Plasmodium falciparum isolates

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Plasmodium falciparum: induction, selection, and characterization of pyrimethamine-resistant mutants

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Pyrimethamine resistant Plasmodium falciparum: overproduction of dihydrofolate reductase by a gene duplication.

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Antifolate drug selection results in duplication and rearrangement of chromosome 7 in Plasmodium chabaudi

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Dihydrofolate reductase mutations and chromosomal changes associated with pyrimethamine resistance of Plasmodium falciparum

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Mutant dihydrofolate reductase-thymidylate synthase genes in pyrimethamine-resistant Plasmodium falciparum with polymorphic chromosome duplications.

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Pyrimethamine resistant mutations in Plasmodium falciparum

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Identification of the four human malaria parasite species in field samples by the polymerase chain reaction and detection of a high prevalence of mixed infections

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Detection of Plasmodium ovale malaria parasites by species-specific 18S rRNA gene amplification.

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Diagnosis of Plasmodium malariae infection by the polymerase chain reaction.

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Molecular cloning and sequence analysis of the Plasmodium falciparum dihydrofolate reductase-thymidylate synthase gene

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Characterisation of the dihydrofolate reductase-thymidylate synthetase gene from human malaria parasites highly resistant to pyrimethamine

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The dihydrofolate reductase domain of rodent malarias: point mutations and pyrimethamine resistance

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Short-term in vitro culture of Plasmodium vivax and P. ovale for drug-susceptibility testing.

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Cultivation of Plasmodium falciparum parasites in a serum-free medium.

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Dihydrofolate Reductase: X-ray Structure of the Binary Complex with Methotrexate

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The structure of mouse L1210 dihydrofolate reductase-drug complexes and the construction of a model of human enzyme

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Point mutations and pyrimethamine resistance in Plasmodium falciparum

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Molecular basis of differential resistance to cycloguanil and pyrimethamine in Plasmodium falciparum malaria

1 reference

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Heterologous expression of active thymidylate synthase-dihydrofolate reductase from Plasmodium falciparum

1 reference

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Antifolate-resistant mutants of Plasmodium falciparum dihydrofolate reductase

1 reference

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Amino acids in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum involved in cycloguanil resistance differ from those involved in pyrimethamine resistance

1 reference

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10.1016/S0166-6851(97)00247-8

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

ResearchGate publication ID

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