(Q32063493)

6 July 2017

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title

Recent progress in the biology, chemistry and structural biology of DNA glycosylases (English)

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6 July 2017

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Schärer OD

1

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PubMed ID

11223884

6 July 2017

Jiricny J

series ordinal

2

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PubMed ID

11223884

6 July 2017

language of work or name

English

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publication date

1 March 2001

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6 July 2017

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6 July 2017

23

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6 July 2017

270-281

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6 July 2017

3

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Molecular mechanism of nucleotide excision repair.

6 July 2017

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Instability and decay of the primary structure of DNA

21 January 2018

1 reference

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An N -Glycosidase from Escherichia coli That Releases Free Uracil from DNA Containing Deaminated Cytosine Residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Long patch base excision repair with purified human proteins. DNA ligase I as patch size mediator for DNA polymerases delta and epsilon

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Reconstitution of proliferating cell nuclear antigen-dependent repair of apurinic/apyrimidinic sites with purified human proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Excision of deoxyribose phosphate residues by DNA polymerase beta during DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Human thymine DNA glycosylase binds to apurinic sites in DNA but is displaced by human apurinic endonuclease 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Uracil-DNA glycosylase (UNG)-deficient mice reveal a primary role of the enzyme during DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Post-replicative base excision repair in replication foci

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Identification of a new uracil-DNA glycosylase family by expression cloning using synthetic inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Cloning and expression of human G/T mismatch-specific thymine-DNA glycosylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Mismatch-specific thymine DNA glycosylase and DNA polymerase beta mediate the correction of G.T mispairs in nuclear extracts from human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

A new class of uracil-DNA glycosylases related to human thymine-DNA glycosylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

3,N4-ethenocytosine, a highly mutagenic adduct, is a primary substrate for Escherichia coli double-stranded uracil-DNA glycosylase and human mismatch-specific thymine-DNA glycosylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

The role of the Escherichia coli mug protein in the removal of uracil and 3,N(4)-ethenocytosine from DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Retinoic acid receptors interact physically and functionally with the T:G mismatch-specific thymine-DNA glycosylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

5-methylcytosine-DNA glycosylase activity is present in a cloned G/T mismatch DNA glycosylase associated with the chicken embryo DNA demethylation complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

The human OGG1 gene: structure, functions, and its implication in the process of carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Identification of human MutY homolog (hMYH) as a repair enzyme for 2-hydroxyadenine in DNA and detection of multiple forms of hMYH located in nuclei and mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Mutagenesis by 8-oxoguanine: an enemy within

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Repair of oxidatively damaged guanine in Saccharomyces cerevisiae by an alternative pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Cloning and characterization of a functional human homolog of Escherichia coli endonuclease III

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Cloning and expression of the cDNA encoding the human homologue of the DNA repair enzyme, Escherichia coli endonuclease III

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Excision of products of oxidative DNA base damage by human NTH1 protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Saccharomyces cerevisiae Ntg1p and Ntg2p: broad specificity N-glycosylases for the repair of oxidative DNA damage in the nucleus and mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

The Saccharomyces cerevisiae homologues of endonuclease III from Escherichia coli, Ntg1 and Ntg2, are both required for efficient repair of spontaneous and induced oxidative DNA damage in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

3-methyladenine DNA glycosylases: structure, function, and biological importance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Mitochondrial targeting of human DNA glycosylases for repair of oxidative DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Mitochondrial DNA repair pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Evidence that MutY and MutM combine to prevent mutations by an oxidatively damaged form of guanine in DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

21 January 2018

Life without DNA repair

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Base excision repair deficient mice lacking the Aag alkyladenine DNA glycosylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Targeted deletion of alkylpurine-DNA-N-glycosylase in mice eliminates repair of 1,N6-ethenoadenine and hypoxanthine but not of 3,N4-ethenocytosine or 8-oxoguanine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Database of mouse strains carrying targeted mutations in genes affecting cellular responses to DNA damage. Version 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

The structural basis of specific base-excision repair by uracil-DNA glycosylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Crystal structure and mutational analysis of human uracil-DNA glycosylase: structural basis for specificity and catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Uracil-DNA glycosylase-DNA substrate and product structures: conformational strain promotes catalytic efficiency by coupled stereoelectronic effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Crystal structure of a G:T/U mismatch-specific DNA glycosylase: mismatch recognition by complementary-strand interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Crystal structure of a thwarted mismatch glycosylase DNA repair complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

MutY catalytic core, mutant and bound adenine structures define specificity for DNA repair enzyme superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Structural basis for the excision repair of alkylation-damaged DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Three-dimensional structure of a DNA repair enzyme, 3-methyladenine DNA glycosylase II, from Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

DNA bending and a flip-out mechanism for base excision by the helix–hairpin–helix DNA glycosylase, Escherichia coli AlkA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Atomic model of a pyrimidine dimer excision repair enzyme complexed with a DNA substrate: structural basis for damaged DNA recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Chemical approaches toward understanding base excision DNA repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

DNA containing a chemically reduced apurinic site is a high affinity ligand for the E. coli formamidopyrimidine-DNA glycosylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Specific binding of a designed pyrrolidine abasic site analog to multiple DNA glycosylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

AP site structural determinants for Fpg specific recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Investigation of the mechanisms of DNA binding of the human G/T glycosylase using designed inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Substrate recognition by Escherichia coli MutY using substrate analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

HhaI methyltransferase flips its target base out of the DNA helix

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

The crystal structure of HaeIII methyltransferase convalently complexed to DNA: an extrahelical cytosine and rearranged base pairing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

21 January 2018

1 reference

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Release of normal bases from intact DNA by a native DNA repair enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Generation of a strong mutator phenotype in yeast by imbalanced base excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Role of electrophilic and general base catalysis in the mechanism of Escherichia coli uracil DNA glycosylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Heteronuclear NMR and crystallographic studies of wild-type and H187Q Escherichia coli uracil DNA glycosylase: electrophilic catalysis of uracil expulsion by a neutral histidine 187

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Separating substrate recognition from base hydrolysis in human thymine DNA glycosylase by mutational analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Mechanisms of enzymatic glycoside hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Snapshots along an enzymatic reaction coordinate: analysis of a retaining beta-glycoside hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Properties of a Recombinant Human Uracil-DNA Glycosylase from the UNG Gene and Evidence that UNG Encodes the Major Uracil-DNA Glycosylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

Mutagenic deamination of cytosine residues in DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-1878%28200103%2923%3A3%3C270%3A%3AAID-BIES1037%3E3.0.CO%3B2-J

10.1002/1521-1878(200103)23:3<270::AID-BIES1037>3.0.CO;2-J

21 January 2018

Identifiers

DOI

1 reference

6 July 2017

1 reference

PubMed ID

11223884