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Molecular mechanisms of human hypertension
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
11239411
retrieved
6 July 2017
review article
1 reference
stated in
Europe PubMed Central
title
Molecular mechanisms of human hypertension
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
11239411
retrieved
6 July 2017
main subject
hypertension
1 reference
based on heuristic
inferred from title
author name string
R P Lifton
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11239411
retrieved
6 July 2017
A G Gharavi
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
11239411
retrieved
6 July 2017
D S Geller
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
11239411
retrieved
6 July 2017
language of work or name
English
0 references
publication date
1 February 2001
1 reference
stated in
Europe PubMed Central
PubMed ID
11239411
retrieved
6 July 2017
published in
Cell
1 reference
stated in
Europe PubMed Central
PubMed ID
11239411
retrieved
6 July 2017
volume
104
1 reference
stated in
Europe PubMed Central
PubMed ID
11239411
retrieved
6 July 2017
page(s)
545-556
1 reference
stated in
Europe PubMed Central
PubMed ID
11239411
retrieved
6 July 2017
issue
4
1 reference
stated in
Europe PubMed Central
PubMed ID
11239411
retrieved
6 July 2017
cites work
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A clinical trial of the effects of dietary patterns on blood pressure. DASH Collaborative Research Group
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Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor
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Association of hypertension with T594M mutation in beta subunit of epithelial sodium channels in black people resident in London.
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Role of gammaENaC subunit in lung liquid clearance and electrolyte balance in newborn mice. Insights into perinatal adaptation and pseudohypoaldosteronism
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Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertension
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Relationship between clinical severity of disease and hemodynamic patterns in essential hypertension
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Use of calcium excretion values to distinguish two forms of primary renal tubular hypokalemic alkalosis: Bartter and Gitelman syndromes
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Brief report: Liddle's syndrome revisited--a disorder of sodium reabsorption in the distal tubule
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Crossref
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Prevalence of Hypertension in the US Adult Population : Results From the Third National Health and Nutrition Examination Survey, 1988-1991
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Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalaemic acidosis, pseudohypoaldosteronism type 1
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Seven lessons from two candidate genes in human essential hypertension: angiotensinogen and epithelial sodium channel
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Understanding hypertension through genetic manipulation in mice
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7 January 2021
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A new locus on chromosome 12p13.3 for pseudohypoaldosteronism type II, an autosomal dominant form of hypertension
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The NHLBI twin study of cardiovascular disease risk factors: methodology and summary of results
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7 January 2021
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Variation in the region of the angiotensin-converting enzyme gene influences interindividual differences in blood pressure levels in young white males.
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Crossref
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Mineralocorticoid action: target tissue specificity is enzyme, not receptor, mediated
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Salt-sensitive hypertension in endothelin-B receptor-deficient rats
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Crossref
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7 January 2021
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Mutations in the mineralocorticoid receptor gene cause autosomal dominant pseudohypoaldosteronism type I
1 reference
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Crossref
reference URL
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7 January 2021
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Activating mineralocorticoid receptor mutation in hypertension exacerbated by pregnancy
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Crossref
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7 January 2021
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High incidence of primary aldosteronism in 199 patients referred with hypertension
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
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7 January 2021
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Blood pressure control--special role of the kidneys and body fluids
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Hypertension caused by a truncated epithelial sodium channel gamma subunit: genetic heterogeneity of Liddle syndrome
1 reference
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Crossref
reference URL
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7 January 2021
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A de novo missense mutation of the beta subunit of the epithelial sodium channel causes hypertension and Liddle syndrome, identifying a proline-rich segment critical for regulation of channel activity
1 reference
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Crossref
reference URL
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7 January 2021
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Type I pseudohypoaldosteronism includes two clinically and genetically distinct entities with either renal or multiple target organ defects
1 reference
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Crossref
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Chromosomal mapping of two genetic loci associated with blood-pressure regulation in hereditary hypertensive rats
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Crossref
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7 January 2021
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QTL influencing blood pressure maps to the region of PPH1 on chromosome 2q31-34 in Old Order Amish
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
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7 January 2021
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Hypertension in mice lacking the gene for endothelial nitric oxide synthase
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Crossref
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7 January 2021
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Early death due to defective neonatal lung liquid clearance in alpha-ENaC-deficient mice.
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Point mutation causing a single amino acid substitution in the hormone binding domain of the glucocorticoid receptor in familial glucocorticoid resistance
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Crossref
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A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular basis of human hypertension: role of angiotensinogen
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Absence of linkage between the angiotensin converting enzyme locus and human essential hypertension
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Structural characterization of normal and mutant human steroid 17 alpha-hydroxylase genes: molecular basis of one example of combined 17 alpha-hydroxylase/17,20 lyase deficiency
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
A novel mouse Nedd4 protein suppresses the activity of the epithelial Na+ channel
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Elevated systolic blood pressure as a cardiovascular risk factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Pulmonary epithelial sodium-channel dysfunction and excess airway liquid in pseudohypoaldosteronism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for a gene influencing blood pressure on chromosome 17. Genome scan linkage results for longitudinal blood pressure phenotypes in subjects from the framingham heart study
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular genetics of human blood pressure variation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
A chimaeric llβ-hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Hereditary hypertension caused by chimaeric gene duplications and ectopic expression of aldosterone synthase
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Environmental and genetic sources of familial aggregation of blood pressure in Tecumseh, Michigan
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular genetics of human hypertension.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multilocus linkage of familial hyperkalaemia and hypertension, pseudohypoaldosteronism type II, to chromosomes 1q31-42 and 17p11-q21
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
MRC trial of treatment of mild hypertension: principal results. Medical Research Council Working Party
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Congenitally defective aldosterone biosynthesis in humans: the involvement of point mutations of the P-450C18 gene (CYP11B2) in CMO II deficient patients
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Trends in the prevalence of hypertension, antihypertensive therapy, and left ventricular hypertrophy from 1950 to 1989.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Human hypertension caused by mutations in the kidney isozyme of 11 beta-hydroxysteroid dehydrogenase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for an unidentified steroid in a child with apparent mineralocorticoid hypertension
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Angiotensinogen gene polymorphisms M235T/T174M: no excess transmission to hypertensive Chinese
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for association and genetic linkage of the angiotensin-converting enzyme locus with hypertension and blood pressure in men but not women in the Framingham Heart Study.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the human CYP11B2 (aldosterone synthase) gene causing corticosterone methyloxidase II deficiency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
eNOS mediates L-arginine-induced inhibition of thick ascending limb chloride flux
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic analysis of inherited hypertension in the rat.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cardiovascular risk factors in a french canadian population: Resolution of genetic and familial environmental effects on blood pressure using twins, adoptees, and extensive information on environmental correlates
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glucocorticoid-remediable aldosteronism in a large kindred: clinical spectrum and diagnosis using a characteristic biochemical phenotype
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
The future of genetic studies of complex human diseases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the mouse beta1-adrenergic receptor gene: developmental and cardiovascular effects
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
A mutation in the epithelial sodium channel causing Liddle disease increases channel activity in the Xenopus laevis oocyte expression system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Severe autosomal dominant hypertension and brachydactyly in a unique Turkish kindred maps to human chromosome 12
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Elevated blood pressures in mice lacking endothelial nitric oxide synthase.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Liddle's syndrome: heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channel
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The activity of the epithelial sodium channel is regulated by clathrin-mediated endocytosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gitelman's variant of Bartter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na-Cl cotransporter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bartter's syndrome, hypokalaemic alkalosis with hypercalciuria, is caused by mutations in the Na-K-2Cl cotransporter NKCC2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic heterogeneity of Bartter's syndrome revealed by mutations in the K+ channel, ROMK
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the chloride channel gene, CLCNKB, cause Bartter's syndrome type III
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
M235T angiotensinogen gene polymorphism and cardiovascular renal risk.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel splice-site mutation in the gamma subunit of the epithelial sodium channel gene in three pseudohypoaldosteronism type 1 families
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mineralocorticoid activity of liquorice: 11-beta-hydroxysteroid dehydrogenase deficiency comes of age
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A Syndrome of Apparent Mineralocorticoid Excess Associated with Defects in the Peripheral Metabolism of Cortisol*
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mutation in CYP11B1 (Arg-448----His) associated with steroid 11 beta-hydroxylase deficiency in Jews of Moroccan origin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900241-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0092-8674(01)00241-0
1 reference
stated in
Europe PubMed Central
PubMed ID
11239411
retrieved
6 July 2017
PubMed ID
11239411
1 reference
stated in
Europe PubMed Central
PubMed ID
11239411
retrieved
6 July 2017
ResearchGate publication ID
12093425
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