(Q33220737)

24 July 2017

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title

Thalidomide in human immunodeficiency virus (HIV) patients. A review of safety considerations (English)

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24 July 2017

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V Günzler

1

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24 July 2017

1 March 1992

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24 July 2017

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24 July 2017

7

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24 July 2017

116-134

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24 July 2017

2

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https://scigraph.springernature.com/pub.10.2165/00002018-199207020-00004

24 July 2017

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cites work

Cyclosporine-induced deterioration in patients with AIDS.

1 reference

12 December 2020

Thalidomide in the treatment of neuro-Behçet's syndrome

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12 December 2020

Thalidomide induces imbalances in T-lymphocyte sub-populations in the circulating blood of healthy males

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12 December 2020

Dysgnathias in the deciduous dentition in dysmelia: contribution to thalidomide embryopathy

1 reference

12 December 2020

Thalidomide in the treatment of chronic discoid lupus erythematosus

1 reference

12 December 2020

Embryotoxic effects of thalidomide derivatives on the non-human primate Callithrix jacchus; 3. Teratogenic potency of the EM 12 enantiomers

1 reference

12 December 2020

Immunological phenomena in leprosy and related diseases

1 reference

12 December 2020

Post-implantation embryo culture: validation with selected compounds for teratogenicity testing

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12 December 2020

Effect of thalidomide on the incidence of iodine-induced and spontaneous lymphocytic thyroiditis and spontaneous diabetes mellitus in the BB/Wor rat

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12 December 2020

[Current use of thalidomide]

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12 December 2020

Thalidomide a promising new treatment for rheumatoid arthritis

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12 December 2020

Thalidomide neuropathy: an electrophysiologic study

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12 December 2020

[Effectiveness of thalidomide in non specific esophageal ulcer in patients with acquired immunodeficiency syndrome]

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12 December 2020

Pyoderma gangrenosum associated with Behçet's disease: treatment with thalidomide

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12 December 2020

Thalidomide-induced peripheral neuropathy. A prospective clinical, neurophysiological and pharmacogenetic evaluation

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12 December 2020

Light and electron microscopic studies of late stages of thalidomide polyneuropathy

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12 December 2020

Cyclosporin A slows collagen triple-helix formation in vivo: indirect evidence for a physiologic role of peptidyl-prolyl cis-trans-isomerase

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12 December 2020

Thalidomide in the Treatment of Recurrent, Necrotic, and Giant Mucocutaneous Aphthae and Aphthosis

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12 December 2020

Reactional status of leprosy

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12 December 2020

Behçet's disease, palmoplantar pustulosis and HLA-B27 treatment with thalidomide

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12 December 2020

Fixed lupus erythematosus (its treatment with thalidomide)

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12 December 2020

Cold haemagglutination disease treated by thalidomide

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12 December 2020

[Thalidomide and Behçet's syndrome]

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12 December 2020

Dysplasia in the mouth, jaw and teeth in dysmelia. Contribution to the thalidomide-embryopathies

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12 December 2020

Thalidomide in hyperalgic pharyngeal ulceration of AIDS

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12 December 2020

Susceptibility to cyclophosphamide and thalidomide of fetal rat limb buds grafted in athymic (nude) mice.

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12 December 2020

The metabolism of thalidomide: the fate of thalidomide and some of its hydrolysis products in various species

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12 December 2020

Treatment of Behçet's disease with thalidomide

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12 December 2020

The neuromuscular manifestations of human immunodeficiency virus infections

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12 December 2020

PROLONGATION OF SKIN HOMOGRAFT SURVIVAL BY THALIDOMIDE.

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12 December 2020

Thalidomide in the treatment of Behçet's syndrome

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12 December 2020

Actinic prurigo (Hutchinson's summer prurigo)

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12 December 2020

Effect of thalidomide-derivatives on limb development in culture

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12 December 2020

A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin

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12 December 2020

An internally-controlled double blind trial of thalidomide in severe erythema nodosum leprosum.

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12 December 2020

Thalidomide in Weber-Christian disease

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12 December 2020

HIV-associated oesophageal ulcers treated with thalidomide

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12 December 2020

[Treatment of aphthosis with thalidomide and with colchicine]

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12 December 2020

Binding of thalidomide by macromolecules in the fetal and maternal rat

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12 December 2020

Clinical experience with a new sedative drug

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12 December 2020

The enantiomers of the teratogenic thalidomide analogue EM 12. 2. Chemical stability, stereoselectivity of metabolism and renal excretion in the marmoset monkey.

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12 December 2020

The effect of thalidomide on experimental autoimmune myasthenia gravis

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12 December 2020

THALIDOMIDE IN THE TREATMENT OF LEPRA REACTIONS

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12 December 2020

Treatment of reactions in leprosy

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12 December 2020

Pyoderma gangrenosum associated with Behçet's syndrome--response to thalidomide

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12 December 2020

Limb bud cell culture for in vitro teratogen screening: validation of an improved assessment method using 51 compounds.

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12 December 2020

Graft-versus-host disease: a review

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12 December 2020

Motor-conduction velocity of cubital nerves in patients with leprosy reactions. Summary of a 13-year observation series during thalidomide therapy

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12 December 2020

Overdosage with thalidomide (distaval)

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12 December 2020

B Lymphocytes in Lepromatous Leprosy

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12 December 2020

Thalidomide and congeners as anti-inflammatory agents

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12 December 2020

Pyoderma gangrenosum with severe pharyngeal ulceration.

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12 December 2020

Unsatisfactory results with thalidomide as a specific treatment for leprosy

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12 December 2020

Disturbance of the blood T:B lymphocyte ratio in lepromatous leprosy. Clinical and immunologic correlations

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12 December 2020

Relationship between teratogeny and structure in the thalidomide field

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12 December 2020

Teratogen metabolism: activation of thalidomide and thalidomide analogues to products that inhibit the attachment of cells to concanavalin A coated plastic surfaces

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12 December 2020

Treatment of refractory rheumatoid arthritis--the thalidomide experience

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12 December 2020

Motor conduction velocity studies in patients with leprosy reaction treated with thalidomide and other drugs

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12 December 2020

Thalidomide for treatment of graft-versus-host disease

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12 December 2020

Effects of thalidomide and its derivatives on human leucocytes cultured in vitro

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12 December 2020

Inefficacy of thalidomide on rat adjuvant-induced arthritis and lack of arthrogenicity of Hansen bacilli

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12 December 2020

[Treatment of prurigo nodularis Hyde with thalidomide]

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12 December 2020

Antithyroid activity of N-phthalyl glutamic acid imide (K17)

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12 December 2020

Prenatal diagnosis of thalidomide syndrome

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12 December 2020

Autoimmune diseases and thalidomide. II. Adjuvant disease, experimental allergic encephalomyelitis and experimental allergic neuritis of the rat.

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12 December 2020

Mechanisms of Mycobacterium leprae-specific T-cell deficiency in lepromatous leprosy

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12 December 2020

[Thalidomide and ulcerative colitis in Behçet's disease]

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12 December 2020

[Beneficial effect of thalidomide in a case of Hailey-Hailey pemphigus. 1 years' trial]

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12 December 2020

Thalidomide in hyperalgic pharyngeal ulceration of AIDS

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12 December 2020

Infection with human immunodeficiency virus in the Pittsburgh transplant population. A study of 583 donors and 1043 recipients, 1981-1986

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12 December 2020

Thalidomide in the treatment of aphthosis and Behçet's disease. 4 years' experience

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12 December 2020

[Treatment of Behcet's syndrome with thalidomide]

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12 December 2020

[Thalidomide in dermatology]

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12 December 2020

Peripheral neuropathy associated with acquired immunodeficiency syndrome. Prevalence and clinical features from a population-based survey

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12 December 2020

Treatment of Jessner-Kanof disease with thalidomide

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12 December 2020

Neuropathy, hypoglycaemia, and adrenal dysfunction during treatment with thalidomide

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12 December 2020

Thalidomide may inhibit proliferation of mesenchyme in human limb buds

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12 December 2020

The effect of thalidomide on skin allografts in mice: survival of the grafts

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12 December 2020

Thalidomide for the therapy of graft-versus-host disease following allogeneic bone marrow transplantation

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12 December 2020

Thalidomide--effect on T cell subsets as a possible mechanism of action

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12 December 2020

[The L-isomer as teratogenic principle of N-phthalyl-DL-glutamic acid]

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12 December 2020

Thalidomide in actinic prurigo

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12 December 2020

Teratogenic effects of proline analogue L-azetidine-2-carboxylic acid in hamster fetuses

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12 December 2020

Thalidomide treatment of prurigo nodularis

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12 December 2020

The potential use of thalidomide in the therapy of graft-versus-host disease--a review of clinical and laboratory information

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12 December 2020

Toxicity and Teratogenicity of Optical Isomers of Thalidomide

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12 December 2020

Ultrastructural changes in blood vessels of peripheral nerves in leprosy neuropathy. II. Borderline, borderline-lepromatous and lepromatous leprosy patients

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12 December 2020

[Clinical studies with a new sedative and hypnotic.]

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12 December 2020

Study with nine thalidomide derivatives in the lepra reaction

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12 December 2020

[Occurrence of a genital hemorrhage in prurigo nodularis treated with thalidomide]

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12 December 2020

Phthaloylisoglutamine, a metabolite of thalidomide

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12 December 2020

The actions of cyclosporin A and FK506 suggest a novel step in the activation of T lymphocytes.

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12 December 2020

Thalidomide and exfoliative dermatitis

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12 December 2020

Combination thalidomide and cyclosporine for cardiac allograft rejection. Comparison with combination methylprednisolone and cyclosporine

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12 December 2020

Evidence for circulating immune complexes in lepromatous leprosy

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12 December 2020

Recurrent aphthous ulcer in patient infected with human immunodeficiency virus: successful treatment with thalidomide.

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12 December 2020

[Cutaneous sarcoidosis. Treatment with thalidomide]

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12 December 2020

Toxic injuries in thalidomide medication

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12 December 2020

Presence of C1q-reactive immune complexes in patients with leprosy

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12 December 2020

Investigation and treatment of orogenital ulceration; studies on a possible mode of action of thalidomide.

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12 December 2020

Unusual cause of pharyngeal ulcerations in AIDS.

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12 December 2020

Results of a double blind study of the influence of thalidomide on the lepra reaction

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12 December 2020

Treatment of severe colitis in Behçet's syndrome with thalidomide (CG-217)

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12 December 2020

Thalidomide for chronic graft-versus-host disease in children

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12 December 2020

Thalidomide in the treatment of sixty cases of chronic discoid lupus erythematosus

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12 December 2020

Neuropathy after intake of thalidomide (distaval)

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12 December 2020

Effect of cyclosporin A on human lymphocyte responses in vitro. I. CsA allows for the expression of alloantigen-activated suppressor cells while preferentially inhibiting the induction of cytolytic effector lymphocytes in MLR

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12 December 2020

A short history of thalidomide embryopathy

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12 December 2020

Successful treatment with thalidomide of acute graft-versus-host disease after bone-marrow transplantation

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12 December 2020

Thalidomide activity in experimental Arthus and anaphylactic reactions

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12 December 2020

Proposed mechanisms of action in thalidomide embryopathy

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12 December 2020

Autoimmune diseases and thalidomide. I. Experimental allergic encephalomyelitis and experimental allergic neuritis of the guinea pig

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12 December 2020

Thalidomide Therapy for Inflammatory Dermatoses

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12 December 2020

Clinical observations in the treatment of leprosy reaction with cyclic imides

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12 December 2020

[On the quantitative determination and the qualitative demonstration of N-phthalylglutamic acid imide (thalidomide).]

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12 December 2020

Thalidomide-induced neuropathy in rheumatoid arthritis patients

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12 December 2020

[Synthesis and teratogenic action of n-hydroxythalidomide]

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12 December 2020

Cutaneous sarcoidosis. Treatment with thalidomide

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12 December 2020

Thalidomide for graft-versus-host disease

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12 December 2020

Electrophysiologic changes in thalidomide neuropathy in the treatment of discoid lupus erythematosus

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12 December 2020

Erythema nodosum leprosum: a clinical manifestation of the arthus phenomenon

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12 December 2020

AUTORADIOGRAPHIC INVESTIGATIONS OF 14-C-LABELLED THALIDOMIDE AND GLUTETHIMIDE IN PREGNANT MICE

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12 December 2020

Thalidomide for graft-versus-host disease after bone marrow transplantation

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12 December 2020

Neurological complications of acquired immune deficiency syndrome: Analysis of 50 patients

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12 December 2020

Renal manifestations of leprosy: Glomerulonephritis, a complication of erythema nodosum leprosum *

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12 December 2020

[Speculative ameloriation of arthritis in Behcet disease with thalidomide. A case report]

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12 December 2020

Thalidomide for severe acute graft-versus-host disease

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12 December 2020

Pharmacological properties of thalidomide (alpha-phthalimido glutarimide), a new sedative hypnotic drug

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12 December 2020

Intestinal graft-versus-host disease is initiated by donor T cells distinct from classic cytotoxic T lymphocytes

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12 December 2020

Leprosy reactional states and their treatment

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12 December 2020

Treatment of resistant aphthous ulceration with thalidomide in patients positive for HIV antibody

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12 December 2020

Aberrations of suppressor T cells in human graft-versus-host disease

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12 December 2020

Development of polyneuropathy during thalidomide therapy

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12 December 2020

Treatment and prevention of acute graft-versus-host disease with thalidomide in a rat model

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12 December 2020

Substrate specificities of the peptidyl prolyl cis-trans isomerase activities of cyclophilin and FK-506 binding protein: evidence for the existence of a family of distinct enzymes

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12 December 2020

Immunological effects of thalidomide. Inactivity of the drug and several of its hydrolysis products in mononucleocyte proliferation tests

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12 December 2020

The immuno-suppressive effect of thalidomide in experimental tuberculosis in guinea-pigs.

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12 December 2020

Teratogenic effect and stereospecificity of a thalidomide metabolite

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12 December 2020

Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin

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12 December 2020

Studies on the teratogenic effect of beta-aminopropionitril in pregnant female mice

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12 December 2020

Mechanisms of reactions in leprosy

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12 December 2020

Thalidomide in the treatment of recurrent necrotic mucocutaneous aphthae

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12 December 2020

Trials with Thalidomide Derivatives in Leprosy Reactions

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12 December 2020

Thalidomide induction of bone marrow transplantation tolerance

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12 December 2020

A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase

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12 December 2020

The fate of the hydrolysis products of thalidomide in the pregnant rabbit

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12 December 2020

[Thalidomide in the treatment of chronic lupus erythematosus]

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12 December 2020

Thalidomide: use and possible mode of action in reactional lepromatous leprosy and in various other conditions

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12 December 2020

Immunosuppression by cyclic imides in the rat

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12 December 2020

Combination low-dose thalidomide and cyclosporine prophylaxis for acute graft-versus-host disease in a rat mismatched model.

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12 December 2020

Effects of cyclosporin on T-cell subsets in human immunodeficiency virus disease

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12 December 2020

Treatment of ulcerative colitis with thalidomide

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12 December 2020

TERATOGENIC ACTIVITY OF THALIDOMIDE AND RELATED COMPOUNDS

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12 December 2020

Thalidomide--a therapy for the immunological consequences of HIV infection?

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12 December 2020

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12 December 2020

Therapy of chronic graft-v-host disease in a rat model

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12 December 2020

The influence of peptidyl-prolyl cis-trans isomerase on the in vitro folding of type III collagen.

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12 December 2020

The spectrum of peripheral neuropathy associated with ARC and AIDS

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12 December 2020

Beneficial effect of thalidomide and ciclosporin combination in heterotopic cardiac transplantation in rats

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12 December 2020

Thalidomide in the treatment of actinic prurigo

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12 December 2020

Jessner's lymphocytic infiltration of the skin. A clinical study of 100 patients

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12 December 2020

Crossover study of thalidomide vs placebo in severe recurrent aphthous stomatitis

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12 December 2020

Thalidomide metabolite inhibits tumor cell attachment to concanavalin A coated surfaces

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12 December 2020

Polyneuropathy after neurosedyn (thalidomide) and its prognosis

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12 December 2020

The treatment of lepra reaction in lepromatous leprosy. Fifteen years' experience with thalidomide

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12 December 2020

Thalidomide therapy. An open trial

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12 December 2020

[On the behavior of thalidomide in the organism. 1.]

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12 December 2020

Neuromuscular diseases associated with human immunodeficiency virus infection

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12 December 2020

Graft-versus-host disease

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12 December 2020

Oesophageal symptoms, their causes, treatment, and prognosis in patients with the acquired immunodeficiency syndrome

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12 December 2020

Effect of Thalidomide on the Graft versus Host Reaction

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12 December 2020

Thalidomide hypersensitivity in AIDS

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12 December 2020

Thalidomide-embryopathies and their effect on dentition

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12 December 2020

Teratogen metabolism: thalidomide activation is mediated by cytochrome P-450

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12 December 2020

[Prolonged survival of homotransplantates of the skin using thalidomide]

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12 December 2020

Plasma pharmacokinetics and urinary excretion of thalidomide after oral dosing in healthy male volunteers

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12 December 2020

Effect of thalidomide on orogenital ulceration

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12 December 2020

[N-phthalyl-glutamic acid imide; experimental studies on a new synthetic product with sedative properties]

1 reference

12 December 2020

Renal allotransplantation in the baboon with chemical immunosuppression

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12 December 2020

Limb anomalies produced by 2,2'-dipyridyl in rats

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12 December 2020

Thalidomide treatment of recurrent erythema multiforme

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12 December 2020

Thalidomide. A study of biochemical teratology

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12 December 2020

Teratogen update: clinical aspects of thalidomide embryopathy--a continuing preoccupation.

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12 December 2020

Thalidomide treatment of subacute cutaneous lupus erythematosus

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12 December 2020

A note on the absorption and excretion of 14C-labelled thalidomide in pregnant mice.

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12 December 2020

The mechanism of the push and pull principle. 8. Endocrine effects of thalidomide and its analogues.

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12 December 2020

Thalidomide neuropathy in the late stage. A clinical documentation

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12 December 2020

[Pyoderma gangrenosum in a child. Treatment with thalidomide (author's transl)]

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12 December 2020

Thalidomide: disposition in rhesus monkey and studies of its hydrolysis in tissues of this and other species.

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12 December 2020

Another chance for thalidomide?

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12 December 2020

Treatment of Moderately Severe Erythema Nodosum Leprosum with Thalidomide - A Double-blind Controlled Trial

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12 December 2020

Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins

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12 December 2020

[The peripheral nervous system and HIV infection. 13 cases]

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12 December 2020

Treatment of aphthae with thalidomide

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12 December 2020

Racemates or enantiomers: regulatory approaches

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12 December 2020

The FDA perspective on the development of stereoisomers

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12 December 2020

Cytomembranous inclusions in the peripheral nerves in AIDS

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12 December 2020

Thalidomide in severe orogenital ulceration

1 reference

12 December 2020

Incidations for thalidomide therapy for leprosy

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12 December 2020

Polymorphous light eruption: Treatment with thalidomide

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12 December 2020

[Thalidomide and the treatment of Behçet's syndrome]

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12 December 2020

Chromatographic separation of racemic thalidomide and teratogenic activity of its enantiomers (author's transl)

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12 December 2020

Thalidomide effects in Behçet's syndrome and pustular vasculitis

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12 December 2020

Generalized lichen planus with erosive lesions of the penis, treated with thalidomide. Report of a case and review of the literature

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12 December 2020

Comparative teratological investigation of compounds structurally and pharmacologically related to thalidomide

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12 December 2020

8-Methoxypsoralen and ultraviolet A therapy for cutaneous manifestations of graft-versus-host disease

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12 December 2020

T cell subsets and graft-versus-host disease

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12 December 2020

Bioactivation of thalidomide by a monkey liver fraction in a rat limb culture system

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12 December 2020

Cytomegalovirus polyradiculoneuropathy in acquired immune deficiency syndrome

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12 December 2020

The sensitive phase in thalidomide embryopathy

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12 December 2020

Thalidomide neurotoxicity

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12 December 2020

Sparing of suppressor cells: a critical action of cyclosporine

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12 December 2020

Treatment of prurigo nodularis with thalidomide

1 reference

12 December 2020

Treatment of prurigo nodularis Hyde using thalidomide

1 reference

12 December 2020

Thalidomide neuropathy: a clinical electrophysiological, and histological follow-up study

1 reference

12 December 2020

Autoimmune diseases: the failure of self tolerance

1 reference

12 December 2020

Embryotoxic effects of thalidomide-derivatives in the non-human primate Callithrix jacchus. I. Effects of 3-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-dioxopiperidine (EM12) on skeletal development

1 reference

12 December 2020

Teratogen metabolism: spontaneous decay products of thalidomide and thalidomide analogues are not bioactivated by liver microsomes

1 reference

12 December 2020

Progressive polyradiculopathy in acquired immune deficiency syndrome

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12 December 2020

Abnormalities of internal organs in thalidomide embryopathy. A contribution to the determination of the sensitivity phase in thalidomide administration during early pregnancy

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12 December 2020

Chronic cutaneous lupus erythematosus. Thalidomide treatment of 11 patients

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12 December 2020

The metabolism of thalidomide: the spontaneous hydrolysis of thalidomide in solution

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12 December 2020

Clinical Correlates of C1q-Precipitating Substances in the Sera of Patients with Leprosy *

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12 December 2020

Thalidomide teratogenesis: evidence for a toxic arene oxide metabolite

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12 December 2020

Evaluation of the pharmacovigilance follow-up of zidovudine

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12 December 2020

Pure cutaneous histiocytosis resembling sinus histiocytosis

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12 December 2020

Recurrent aphthous stomatitis of the Behçet's type: successful treatment with thalidomide

1 reference

12 December 2020

[Thalidomide in the treatment of discoid lupus erythematosus (D.L.E.) (author's transl)]

1 reference

12 December 2020

Thalidomide-induced peripheral neuropathy. Effect of serum factor on nerve cultures

1 reference

12 December 2020

Significant response of oral aphthosis to thalidomide treatment

1 reference

12 December 2020

The enantiomers of the teratogenic thalidomide analogue EM 12: 1. Chiral inversion and plasma pharmacokinetics in the marmoset monkey

1 reference

12 December 2020

Erythropoietin release in renal allografted baboons, with and without immunosuppression

1 reference

12 December 2020

Neuropathies caused by thalidomide

1 reference

12 December 2020

The cytosolic-binding protein for the immunosuppressant FK-506 is both a ubiquitous and highly conserved peptidyl-prolyl cis-trans isomerase

1 reference

12 December 2020

Teratogenic drugs inhibit tumour cell attachment to lectin-coated surfaces

1 reference

12 December 2020

Serum cyclosporine concentration and risk of acute graft-versus-host disease after allogeneic marrow transplantation

1 reference

12 December 2020

The fate of[14C]thalidomide in the pregnant rabbit

1 reference

12 December 2020

10.2165/00002018-199207020-00004

Identifiers

DOI

1 reference

PubMed ID

1605898

Dimensions Publication ID

24 July 2017

0 references

1 reference

PubMed ID

1605898