(Q33255059)

24 July 2017

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title

Genome-scale loss-of-function screening with a lentiviral RNAi library (English)

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24 July 2017

4

Eric S Lander

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24 July 2017

2

Nir Hacohen

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William C Hahn

series ordinal

3

object named as

William C Hahn

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24 July 2017

1

David E Root

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24 July 2017

5

David M Sabatini

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PubMed ID

16929317

24 July 2017

language of work or name

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1 September 2006

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24 July 2017

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24 July 2017

3

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24 July 2017

715-719

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24 July 2017

9

1 reference

https://scigraph.springernature.com/pub.10.1038/nmeth924

24 July 2017

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cites work

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

1 reference

7 January 2021

New tools for functional mammalian cancer genetics

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7 January 2021

Unlocking the potential of the human genome with RNA interference

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7 January 2021

Building mammalian signalling pathways with RNAi screens

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7 January 2021

A large-scale RNAi screen in human cells identifies new components of the p53 pathway

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7 January 2021

An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors

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7 January 2021

A genetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity

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7 January 2021

A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen

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7 January 2021

A loss-of-function RNA interference screen for molecular targets in cancer

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7 January 2021

A resource for large-scale RNA-interference-based screens in mammals.

1 reference

7 January 2021

Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosis

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7 January 2021

A genetic screen for candidate tumor suppressors identifies REST

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7 January 2021

A third-generation lentivirus vector with a conditional packaging system

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7 January 2021

Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences

1 reference

7 January 2021

Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells

1 reference

7 January 2021

Second-generation shRNA libraries covering the mouse and human genomes

1 reference

7 January 2021

Functional siRNAs and miRNAs Exhibit Strand Bias

1 reference

7 January 2021

Asymmetry in the assembly of the RNAi enzyme complex

1 reference

7 January 2021

3' UTR seed matches, but not overall identity, are associated with RNAi off-targets

1 reference

7 January 2021

Expression profiling reveals off-target gene regulation by RNAi

1 reference

7 January 2021

Cancer-associated PP2A Aalpha subunits induce functional haploinsufficiency and tumorigenicity

1 reference

7 January 2021

The telomerase reverse transcriptase regulates chromatin state and DNA damage responses.

1 reference

7 January 2021

Identifiers

DOI

10.1038/NMETH924

1 reference

PubMed ID

16929317

Dimensions Publication ID

24 July 2017

0 references

1 reference

PubMed ID

16929317