(Q33276455)

25 July 2017

Lead-like, drug-like or "Pub-like": how different are they? (English)

1 reference

25 July 2017

Cristian G Bologa

6

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Tudor I Oprea

object named as

Tudor I Oprea

1

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author name string

Tharun Kumar Allu

2

1 reference

25 July 2017

Dan C Fara

3

1 reference

25 July 2017

Ramona F Rad

4

1 reference

25 July 2017

Lili Ostopovici

5

1 reference

25 July 2017

1 January 2007

1 reference

Journal of Computer - Aided Molecular Design

25 July 2017

1 reference

25 July 2017

21

1 reference

25 July 2017

113-119

1 reference

25 July 2017

1-3

1 reference

https://scigraph.springernature.com/pub.10.1007/s10822-007-9105-3

25 July 2017

0 references

cites work

Virtual Computational Chemistry Laboratory – Design and Description

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2807375

Rapid evaluation of synthetic and molecular complexity for in silico chemistry

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2807375

NIH Molecular Libraries Initiative

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2807375

Application of ALOGPS 2.1 to predict log D distribution coefficient for Pfizer proprietary compounds

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2807375

A comparison of physiochemical property profiles of development and marketed oral drugs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2807375

Is there a difference between leads and drugs? A historical perspective

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2807375

Cheminformatics: a tool for decision-makers in drug discovery.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2807375

Molecular complexity and its impact on the probability of finding leads for drug discovery

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2807375

Property distribution of drug-related chemical databases.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2807375

Application of ALOGPS to predict 1-octanol/water distribution coefficients, logP, and logD, of AstraZeneca in-house database

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2807375

Simultaneous prediction of aqueous solubility and octanol/water partition coefficient based on descriptors derived from molecular structure

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2807375

Prediction of n-octanol/water partition coefficients from PHYSPROP database using artificial neural networks and E-state indices.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2807375

Prediction of aqueous solubility of organic compounds by the general solubility equation (GSE).

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2807375

Drugs, leads, and drug-likeness: an analysis of some recently launched drugs

31 October 2018

1 reference

12 December 2020

Innovation in the pharmaceutical industry

1 reference

12 December 2020

Current trends in lead discovery: are we looking for the appropriate properties?

1 reference

12 December 2020

A provisional biopharmaceutical classification of the top 200 oral drug products in the United States, Great Britain, Spain, and Japan

1 reference

12 December 2020

10.1007/S10822-007-9105-3

Identifiers

DOI

1 reference

journals/jcamd/OpreaAFROB07

25 July 2017

1 reference

DBLP Dataset 2021-01-02

28 January 2021

1 reference

25 July 2017

1 reference