(Q33455616)

26 July 2017

Selective killing of tumors deficient in methylthioadenosine phosphorylase: a novel strategy (English)

1 reference

26 July 2017

Martin Lubin

1

1 reference

PubMed ID

19478948

26 July 2017

Adam Lubin

series ordinal

2

1 reference

PubMed ID

19478948

26 July 2017

language of work or name

English

0 references

publication date

29 May 2009

1 reference

26 July 2017

1 reference

26 July 2017

4

1 reference

26 July 2017

e5735

1 reference

26 July 2017

5

1 reference

Creative Commons Attribution 4.0 International

26 July 2017

start time

29 May 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Novel trypanocidal analogs of 5'-(methylthio)-adenosine

21 June 2018

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A transition state analogue of 5'-methylthioadenosine phosphorylase induces apoptosis in head and neck cancers

21 June 2018

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Aminopropyltransferases: function, structure and genetics

21 June 2018

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Homozygous deletions of methylthioadenosine phosphorylase in human biliary tract cancers

21 June 2018

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PNP anticancer gene therapy

21 June 2018

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EFA (9-beta-D-erythrofuranosyladenine) is an effective salvage agent for methylthioadenosine phosphorylase-selective therapy of T-cell acute lymphoblastic leukemia with L-alanosine

21 June 2018

1 reference

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Status of methylthioadenosine phosphorylase and its impact on cellular response to L-alanosine and methylmercaptopurine riboside in human soft tissue sarcoma cells.

21 June 2018

1 reference

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Characterization of methylthioadenosin phosphorylase (MTAP) expression in malignant melanoma

21 June 2018

1 reference

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Homozygous deletion of CDKN2A and codeletion of the methylthioadenosine phosphorylase gene in the majority of pleural mesotheliomas.

21 June 2018

1 reference

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Frequent deletion in the methylthioadenosine phosphorylase gene in T-cell acute lymphoblastic leukemia: strategies for enzyme-targeted therapy

21 June 2018

1 reference

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Karnofsky memorial lecture. Ode to methotrexate

21 June 2018

1 reference

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Methylthioadenosine phosphorylase deficiency in human non-small cell lung cancers.

21 June 2018

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5'-Deoxy-5'-methylthioadenosine phosphorylase and p16INK4 deficiency in multiple tumor cell lines.

21 June 2018

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Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma

21 June 2018

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Effects of inhibitors of spermidine and spermine synthesis on polyamine concentrations and growth of transformed mouse fibroblasts

21 June 2018

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Trends in the biochemical pharmacology of 5'-deoxy-5'-methylthioadenosine

21 June 2018

1 reference

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Selective killing of human malignant cell lines deficient in methylthioadenosine phosphorylase, a purine metabolic enzyme

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684647

Methionine synthesis from 5'-methylthioadenosine by tumour cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684647

Phosphate-stimulated breakdown of 5′-methylthioadenosine by rat ventral prostate

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684647

Analogs of 5'-deoxy-5'-(methylthio)adenosine.

21 June 2018

1 reference

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5'-Deoxy-5'-methylthioadenosine phosphorylase--III. Role of the enzyme in the metabolism and action of 5'-halogenated adenosine analogs

21 June 2018

1 reference

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Biochemical basis of the prevention of 6-thiopurine toxicity by the nucleobases, hypoxanthine and adenine

21 June 2018

1 reference

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Absence of methylthioadenosine phosphorylase in human gliomas

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684647

Methylthioadenosine nucleoside phosphorylase deficiency in methylthio-dependent cancer cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684647

A long-acting suicide gene toxin, 6-methylpurine, inhibits slow growing tumors after a single administration

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0005735

5'-Methylthioadenosine administration prevents lipid peroxidation and fibrogenesis induced in rat liver by carbon-tetrachloride intoxication.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0005735

Design, synthesis, and biological evaluation of novel human 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP) substrates

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0005735

A phase II multicenter study of L-alanosine, a potent inhibitor of adenine biosynthesis, in patients with MTAP-deficient cancer

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684647

Methylthioadenosine phosphorylase gene deletions are common in osteosarcoma

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684647

In vivo potentiation of 5-fluorouracil cytotoxicity against AKR leukemia by purines, pyrimidines, and their nucleosides and deoxynucleosides

31 October 2018

1 reference

12 December 2020

Modulation of fluoropyrimidine metabolism in L1210 cells by L-alanosine

1 reference

12 December 2020

5-Methylthioribose. Its effects and function in mammalian cells

1 reference

12 December 2020

Effect of 5'-methylthioadenosine (a naturally occurring nucleoside) on murine hematopoiesis

1 reference

12 December 2020

Studies on human serum 5'-deoxy-5'-methylthioadenosine phosphorylase: molecular properties and clinical perspectives

1 reference

12 December 2020

The effects of the folic acid antagonists and 2,6-diaminopurine on neoplastic disease, with special reference to acute leukemia

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0005735

Identifiers

DOI

1 reference

26 July 2017

0 references

1 reference

26 July 2017

1 reference

PubMed ID

19478948