(Q33534707)

27 July 2017

1 reference

title

Signaling by the germinal center kinase family of protein kinases (English)

1 reference

27 July 2017

J M Kyriakis

1

1 reference

PubMed ID

10026130

27 July 2017

language of work or name

English

0 references

publication date

1 February 1999

1 reference

Journal of Biological Chemistry

27 July 2017

1 reference

27 July 2017

274

1 reference

27 July 2017

5259-5262

1 reference

27 July 2017

9

1 reference

Sounding the alarm: protein kinase cascades activated by stress and inflammation

27 July 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

MAP kinase pathways in yeast: for mating and more

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

Raf meets Ras: completing the framework of a signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

AP-1 function and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

MKK7 is a stress-activated mitogen-activated protein kinase kinase functionally related to hemipterous.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

Cloning of rat MEK kinase 1 cDNA reveals an endogenous membrane-associated 195-kDa protein with a large regulatory domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

The mixed lineage kinase SPRK phosphorylates and activates the stress-activated protein kinase activator, SEK-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

MST/MLK2, a member of the mixed lineage kinase family, directly phosphorylates and activates SEK1, an activator of c-Jun N-terminal kinase/stress-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

A human homolog of the yeast Ssk2/Ssk22 MAP kinase kinase kinases, MTK1, mediates stress-induced activation of the p38 and JNK pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

Chp, a homologue of the GTPase Cdc42Hs, activates the JNK pathway and is implicated in reorganizing the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

A new rac target POSH is an SH3-containing scaffold protein involved in the JNK and NF-kappaB signalling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

Emerging from the Pak: the p21-activated protein kinase family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

Human HPK1, a novel human hematopoietic progenitor kinase that activates the JNK/SAPK kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

NIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

TNF-mediated activation of the stress-activated protein kinase pathway: TNF receptor-associated factor 2 recruits and activates germinal center kinase related

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

The Ste20-like protein kinase, Mst1, dimerizes and contains an inhibitory domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

Newly identified stress-responsive protein kinases, Krs-1 and Krs-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

Cloning and characterization of a human STE20-like protein kinase with unusual cofactor requirements

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

LOK is a novel mouse STE20-like protein kinase that is expressed predominantly in lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

The Drosophila Ste20-related kinase misshapen is required for embryonic dorsal closure and acts through a JNK MAPK module on an evolutionarily conserved signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

Characterization and cloning of a Dictyostelium Ste20-like protein kinase that phosphorylates the actin-binding protein severin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

Mutation of the SPS1-encoded protein kinase of Saccharomyces cerevisiae leads to defects in transcription and morphology during spore formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

CDC15, an essential cell cycle gene in Saccharomyces cerevisiae, encodes a protein kinase domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

Tumor necrosis factor signaling to stress-activated protein kinase (SAPK)/Jun NH2-terminal kinase (JNK) and p38. Germinal center kinase couples TRAF2 to mitogen-activated protein kinase/ERK kinase kinase 1 and SAPK while receptor interacting [...]

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

CD30 is a CD40-inducible molecule that negatively regulates CD40-mediated immunoglobulin class switching in non-antigen-selected human B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

In its active form, the GTP-binding protein rab8 interacts with a stress-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

GTPases: multifunctional molecular switches regulating vesicular traffic

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

SH2/SH3 adaptor proteins can link tyrosine kinases to a Ste20-related protein kinase, HPK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.9.5259

21 January 2018

Identifiers

DOI

10.1074/JBC.274.9.5259

1 reference

27 July 2017

1 reference

PubMed ID

10026130