(Q33541966)

27 July 2017

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title

Interleukin-18 and interleukin-1 beta: two cytokine substrates for ICE (caspase-1). (English)

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27 July 2017

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2

Dinarello CA

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27 July 2017

Fantuzzi G

1

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27 July 2017

1 January 1999

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Journal of Clinical Immunology

27 July 2017

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27 July 2017

19

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27 July 2017

1-11

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27 July 2017

1

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https://scigraph.springernature.com/pub.10.1023/a:1020506300324

27 July 2017

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Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity

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12 December 2020

Human neutrophil elastase abolishes interleukin-8 chemotactic activity

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12 December 2020

Early colonisation of a local inflammatory lesion and its relationship to changes in systemic leucocyte availability: a study of turpentine-induced lesions in the rat

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12 December 2020

Generation of biologically active IL-1 beta by matrix metalloproteinases: a novel caspase-1-independent pathway of IL-1 beta processing.

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12 December 2020

The interleukin-1 receptor accessory protein (IL-1RAcP) is essential for IL-1-induced activation of interleukin-1 receptor-associated kinase (IRAK) and stress-activated protein kinases (SAP kinases)

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12 December 2020

IFN-gamma-inducing factor (IGIF) is a costimulatory factor on the activation of Th1 but not Th2 cells and exerts its effect independently of IL-12.

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12 December 2020

Inhibition of in vitro immunoglobulin production by IL-12 in murine chronic graft-vs.-host disease: synergism with IL-18.

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12 December 2020

The kinetics of interleukin 1 secretion from activated monocytes. Differences between interleukin 1 alpha and interleukin 1 beta

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12 December 2020

Purification and characterization of a unique human interleukin 1 from the tumor cell line U937.

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12 December 2020

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12 December 2020

Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme

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12 December 2020

Hyperosmotic stress as a stimulant for proinflammatory cytokine production

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12 December 2020

Activated neutrophils express proteinase 3 on their plasma membrane in vitro and in vivo

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12 December 2020

Regulation of IL-18 (IFN-gamma-inducing factor) gene expression

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12 December 2020

IL-18 augments perforin-dependent cytotoxicity of liver NK-T cells

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12 December 2020

Measurements of proteinase 3 and its complexes with alpha 1-proteinase inhibitor and anti-neutrophil cytoplasm antibodies (ANCA) in plasma

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12 December 2020

A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

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12 December 2020

Relation between diaphragmatic mast‐cell activity and exudate formation in acute experimental pleurisy

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12 December 2020

A novel costimulatory factor for gamma interferon induction found in the livers of mice causes endotoxic shock

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12 December 2020

Tissue and T cell distribution of precursor and mature IL-16

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12 December 2020

Cloning of cDNA for proteinase 3: a serine protease, antibiotic, and autoantigen from human neutrophils

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12 December 2020

Caspases: enemies within

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12 December 2020

Granzyme A is an interleukin 1 beta-converting enzyme

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12 December 2020

Resistance to fever induction and impaired acute-phase response in interleukin-1 beta-deficient mice

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12 December 2020

Interleukin 18 together with interleukin 12 inhibits IgE production by induction of interferon-gamma production from activated B cells.

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12 December 2020

Crystal structure of the cysteine protease interleukin-1 beta-converting enzyme: a (p20/p10)2 homodimer

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12 December 2020

Interleukin-18 regulation of interferon gamma production and cell proliferation as shown in interleukin-1beta-converting enzyme (caspase-1)-deficient mice

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12 December 2020

Mechanism by which U937 promonocytic cells inactivate human interferon-gamma

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12 December 2020

Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha

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12 December 2020

Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

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12 December 2020

Production of IL-18 (IFN-gamma-inducing factor) messenger RNA and functional protein by murine keratinocytes.

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12 December 2020

Interleukin-8 processing by neutrophil elastase, cathepsin G and proteinase-3.

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12 December 2020

Suppression of apoptosis by nitric oxide via inhibition of interleukin-1beta-converting enzyme (ICE)-like and cysteine protease protein (CPP)-32-like proteases

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12 December 2020

Release of neutrophil proteinase 4(3) and leukocyte elastase during phagocytosis and their interaction with proteinase inhibitors

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12 December 2020

Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

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12 December 2020

Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production.

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12 December 2020

Effective treatment of models of multiple sclerosis by matrix metalloproteinase inhibitors.

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12 December 2020

Structure and mechanism of interleukin-1 beta converting enzyme

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12 December 2020

IL-1Rrp is a novel receptor-like molecule similar to the type I interleukin-1 receptor and its homologues T1/ST2 and IL-1R AcP

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12 December 2020

Interleukins in the control of osteoclast differentiation

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12 December 2020

IL-1-converting enzyme requires aspartic acid residues for processing of the IL-1 beta precursor at two distinct sites and does not cleave 31-kDa IL-1 alpha

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12 December 2020

Interleukin-1 beta converting enzyme inhibition blocks progression of type II collagen-induced arthritis in mice

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12 December 2020

IFN-gamma-inducing factor up-regulates Fas ligand-mediated cytotoxic activity of murine natural killer cell clones.

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12 December 2020

Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex

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12 December 2020

Murine macrophages secrete interferon gamma upon combined stimulation with interleukin (IL)-12 and IL-18: A novel pathway of autocrine macrophage activation

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12 December 2020

Chymase cleavage of stem cell factor yields a bioactive, soluble product

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12 December 2020

Proteinase 3, the target antigen of anticytoplasmic antibodies circulating in Wegener's granulomatosis. Immunolocalization in normal and pathologic tissues

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12 December 2020

Biologic basis for interleukin-1 in disease

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12 December 2020

Severity and mortality of experimental pancreatitis are dependent on interleukin-1 converting enzyme (ICE)

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12 December 2020

The inflammatory response in interleukin-1 beta-deficient mice: comparison with other cytokine-related knock-out mice.

1 reference

12 December 2020

Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase

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12 December 2020

Processing of precursor interleukin 1 beta and inflammatory disease

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12 December 2020

Nitric oxide prevents IL-1beta and IFN-gamma-inducing factor (IL-18) release from macrophages by inhibiting caspase-1 (IL-1beta-converting enzyme)

1 reference

12 December 2020

Elevations of neutrophil proteinase 3 in serum of patients with Wegener's granulomatosis and polyarteritis nodosa

1 reference

12 December 2020

Generation of biologically active interleukin-1 beta by proteolytic cleavage of the inactive precursor.

1 reference

12 December 2020

The demonstration of the role of mediators in turpentine pleurisy in rats by experimental suppression of the inflammatory changes

1 reference

12 December 2020

Coagulation of whole blood stimulates interleukin-1 beta gene expression

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12 December 2020

Human ICE/CED-3 protease nomenclature

1 reference

12 December 2020

TRAF6 is a signal transducer for interleukin-1

1 reference

12 December 2020

Signal transduction pathways activated by the IL-1 receptor family: ancient signaling machinery in mammals, insects, and plants.

1 reference

12 December 2020

Purification and characterization of the human interleukin-18 receptor

1 reference

12 December 2020

Induction of interferon-gamma inducing factor in the adrenal cortex

1 reference

12 December 2020

Metalloproteinase inhibitor prevents hepatic injury in endotoxemic mice

1 reference

12 December 2020

Ultrastructural localization of proteinase 3, the target antigen of anti-cytoplasmic antibodies circulating in Wegener's granulomatosis

1 reference

12 December 2020

Interleukin-18 (IFNgamma-inducing factor) induces IL-8 and IL-1beta via TNFalpha production from non-CD14+ human blood mononuclear cells

1 reference

12 December 2020

IL-1 beta is secreted by activated murine macrophages as biologically inactive precursor.

1 reference

12 December 2020

IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: synergism with IL-18 for IFN-gamma production

1 reference

12 December 2020

Interleukin-18 activates NF-kappaB in murine T helper type 1 cells

1 reference

12 December 2020

Release of immunoreactive human neutrophil proteinase 4, normally and in peritonitis

1 reference

12 December 2020

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

1 reference

12 December 2020

Biologically active, alternatively processed interleukin-1 beta in psoriatic scales

1 reference

12 December 2020

A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells

1 reference

12 December 2020

Expression of interleukin-18 in murine contact hypersensitivity

1 reference

12 December 2020

Cloning of the cDNA for human IFN-gamma-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein

1 reference

12 December 2020

Cloning of a novel receptor subunit, AcPL, required for interleukin-18 signaling

1 reference

12 December 2020

Defective NK cell activity and Th1 response in IL-18-deficient mice

1 reference

12 December 2020

Interleukin-1 beta converting enzyme requires oligomerization for activity of processed forms in vivo

1 reference

12 December 2020

Involvement of caspase-1 and caspase-3 in the production and processing of mature human interleukin 18 in monocytic THP.1 cells

1 reference

12 December 2020

Cardiopulmonary bypass causes release of leukocyte proteinase-3

1 reference

12 December 2020

Formation of active IL-1 beta from pro-IL-1 beta catalyzed by stratum corneum chymotryptic enzyme in vitro

1 reference

12 December 2020

Interleukin-18 (interferon-gamma-inducing factor) is produced by osteoblasts and acts via granulocyte/macrophage colony-stimulating factor and not via interferon-gamma to inhibit osteoclast formation

1 reference

12 December 2020

Processing and activation of pro-interleukin-16 by caspase-3

1 reference

12 December 2020

IGIF does not drive Th1 development but synergizes with IL-12 for interferon-gamma production and activates IRAK and NFkappaB.

1 reference

12 December 2020

Interferon-gamma-inducing factor enhances T helper 1 cytokine production by stimulated human T cells: synergism with interleukin-12 for interferon-gamma production

1 reference

12 December 2020

The interleukin-1 receptor complex and interleukin-1 signal transduction

1 reference

12 December 2020

In vitro processing of human tumor necrosis factor-alpha.

1 reference

12 December 2020

Interleukin 18 stimulates HIV type 1 in monocytic cells

1 reference

12 December 2020

IL-12 and IL-18 differentially regulate the transcriptional activity of the human IFN-gamma promoter in primary CD4+ T lymphocytes.

1 reference

12 December 2020

Multiple biological activities of human recombinant interleukin 1.

1 reference

12 December 2020

NF-kappa B activation by interleukin-1 (IL-1) requires an IL-1 receptor-associated protein kinase activity.

1 reference

12 December 2020

Interferon-gamma-inducing factor, a novel cytokine, enhances Fas ligand-mediated cytotoxicity of murine T helper 1 cells

1 reference

12 December 2020

Interleukin-18 activates the IRAK-TRAF6 pathway in mouse EL-4 cells

1 reference

12 December 2020

Response to local inflammation of IL-1 beta-converting enzyme- deficient mice

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12 December 2020

Interaction of transforming growth factor beta (TGF beta) with proteinase 3

1 reference

12 December 2020

Recruitment of IRAK to the interleukin 1 receptor complex requires interleukin 1 receptor accessory protein

1 reference

12 December 2020

Human endothelial cells express proteinase 3, the target antigen of anticytoplasmic antibodies in Wegener's granulomatosis

1 reference

12 December 2020

Leukocyte activation detected by increased plasma levels of inflammatory mediators in patients with ischemic cerebrovascular diseases.

1 reference

12 December 2020

Interleukin-18 induces activation and association of p56(lck) and MAPK in a murine TH1 clone

1 reference

12 December 2020

Alpha-globulins suppress human leukocyte tumor necrosis factor secretion.

1 reference

12 December 2020

Interleukin 18 enhances Fas ligand expression and induces apoptosis in Fas-expressing human myelomonocytic KG-1 cells

1 reference

12 December 2020

A matrix metalloproteinase inhibitor prevents processing of tumor necrosis factor alpha (TNF alpha) and abrogates endotoxin-induced lethality

1 reference

12 December 2020

Nitric oxide reversibly inhibits seven members of the caspase family via S-nitrosylation

1 reference

12 December 2020

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

1 reference

12 December 2020

Determination of proteinase 3-alpha 1-antitrypsin complexes in inflammatory fluids

1 reference

12 December 2020

In vivo evidence for protease-catalysed mechanism providing bioactive tumor necrosis factor alpha

1 reference

12 December 2020

Interleukin-18/interferon-gamma-inducing factor, a novel cytokine, up-regulates ICAM-1 (CD54) expression in KG-1 cells

1 reference

12 December 2020

Effect of endotoxin in IL-1 beta-deficient mice

1 reference

12 December 2020

Proteolysis of human tumor necrosis factor (TNF) by endo- and exopeptidases: process of proteolysis and formation of active fragments

1 reference

12 December 2020

Structure-activity relationships of interleukin-8 determined using chemically synthesized analogs. Critical role of NH2-terminal residues and evidence for uncoupling of neutrophil chemotaxis, exocytosis, and receptor binding activities

1 reference

12 December 2020

Cloning of a new cytokine that induces IFN-gamma production by T cells

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1020506300324

1 reference

PubMed ID

10080100

Dimensions Publication ID

27 July 2017

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1 reference

PubMed ID

10080100