(Q33560926)

28 July 2017

title

A series of 18F-labelled pyridinylphenyl amides as subtype-selective radioligands for the dopamine D3 receptor (English)

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28 July 2017

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Peter Gmeiner

7

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Olaf Prante

8

object named as

Olaf Prante

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28 July 2017

Carsten Hocke

1

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28 July 2017

Simone Maschauer

2

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28 July 2017

Harald Hübner

3

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28 July 2017

Stefan Löber

4

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28 July 2017

Wolfgang Utz

5

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28 July 2017

Torsten Kuwert

6

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28 July 2017

publication date

1 June 2010

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28 July 2017

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28 July 2017

volume

5

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28 July 2017

issue

6

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28 July 2017

page(s)

941-948

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Dopamine and the diseased brain

28 July 2017

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Structure-affinity relationship study on N-[4-(4-arylpiperazin-1-yl)butyl]arylcarboxamides as potent and selective dopamine D(3) receptor ligands.

21 January 2018

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21 January 2018

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Design and synthesis of [(2,3-dichlorophenyl)piperazin-1-yl]alkylfluorenylcarboxamides as novel ligands selective for the dopamine D3 receptor subtype

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Interactive SAR studies: rational discovery of super-potent and highly selective dopamine D3 receptor antagonists and partial agonists

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Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor

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N-(4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl, butenyl and butynyl)arylcarboxamides as novel dopamine D(3) receptor antagonists

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18F-Labeled FAUC 346 and BP 897 derivatives as subtype-selective potential PET radioligands for the dopamine D3 receptor.

21 January 2018

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Positron emission tomographic evaluation of the putative dopamine-D3 receptor ligand, [11C]RGH-1756 in the monkey brain

21 January 2018

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Brain region binding of the D2/3 agonist [11C]-(+)-PHNO and the D2/3 antagonist [11C]raclopride in healthy humans

21 January 2018

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Radiosynthesis and evaluation of [11C]-(+)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol as a potential radiotracer for in vivo imaging of the dopamine D2 high-affinity state with positron emission tomography.

21 January 2018

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Syntheses and in vitro evaluation of fluorinated naphthoxazines as dopamine D2/D3 receptor agonists: radiosynthesis, ex vivo biodistribution and autoradiography of [(18)F]F-PHNO.

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CoMFA and CoMSIA investigations revealing novel insights into the binding modes of dopamine D3 receptor agonists

21 January 2018

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Structure-selectivity investigations of D2-like receptor ligands by CoMFA and CoMSIA guiding the discovery of D3 selective PET radioligands

21 January 2018

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Synthesis and evaluation of 18F-labeled dopamine D3 receptor ligands as potential PET imaging agents

21 January 2018

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Fancy bioisosteres: metallocene-derived G-protein-coupled receptor ligands with subnanomolar binding affinity and novel selectivity profiles

21 January 2018

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Conjugated enynes as nonaromatic catechol bioisosteres: synthesis, binding experiments, and computational studies of novel dopamine receptor agonists recognizing preferentially the D(3) subtype

21 January 2018

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Pharmacology of human dopamine D3 receptor expressed in a mammalian cell line: comparison with D2 receptor

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Modulation of Intracellular Cyclic AMP Levels by Different Human Dopamine D4 Receptor Variants

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7 January 2021

Fancy bioisosteres: novel paracyclophane derivatives as super-affinity dopamine D3 receptor antagonists

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21 January 2018

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N-(4-(4-(2-Halogenophenyl)piperazin-1-yl)butyl) substituted cinnamoyl amide derivatives as dopamine D2 and D3 receptor ligands

21 January 2018

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CoMFA and CoMSIA investigations of dopamine D3 receptor ligands leading to the prediction, synthesis, and evaluation of rigidized FAUC 365 analogues

21 January 2018

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Dopamine D3 receptor antagonism inhibits cocaine-seeking and cocaine-enhanced brain reward in rats

21 January 2018

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7 January 2021

Opposing roles for dopamine D2 and D3 receptors on neurotensin mRNA expression in nucleus accumbens

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7 January 2021

NGB 2904 and NGB 2849: two highly selective dopamine D3 receptor antagonists

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7 January 2021

Aromatic substituent constants for structure-activity correlations

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7 January 2021

Identifiers

DOI

10.1002/CMDC.201000067

1 reference

release_n4anskambjgwzeqsdynbg22epy

28 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/n4anskambjgwzeqsdynbg22epy

24 November 2022

mapped directly with Wikidata item

1 reference