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Deconstructing type 2 diabetes
scientific article
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
10199397
retrieved
28 July 2017
review article
1 reference
stated in
Europe PubMed Central
title
Deconstructing type 2 diabetes
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10199397
retrieved
28 July 2017
main subject
type 2 diabetes
0 references
author name string
Taylor SI
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10199397
retrieved
28 July 2017
language of work or name
English
0 references
publication date
1 April 1999
1 reference
stated in
Europe PubMed Central
PubMed ID
10199397
retrieved
28 July 2017
published in
Cell
1 reference
stated in
Europe PubMed Central
PubMed ID
10199397
retrieved
28 July 2017
volume
97
1 reference
stated in
Europe PubMed Central
PubMed ID
10199397
retrieved
28 July 2017
page(s)
9-12
1 reference
stated in
Europe PubMed Central
PubMed ID
10199397
retrieved
28 July 2017
issue
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10199397
retrieved
28 July 2017
cites work
Early neonatal death in mice homozygous for a null allele of the insulin receptor gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980709-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A common amino acid polymorphism in insulin receptor substrate-1 causes impaired insulin signaling. Evidence from transfection studies
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980709-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin-stimulated insulin secretion in single pancreatic beta cells.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980709-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Glucokinase mutations, insulin secretion, and diabetes mellitus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980709-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980709-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980709-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation in hepatocyte nuclear factor-1 beta gene (TCF2) associated with MODY.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980709-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980709-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Impaired glucose tolerance in mice with a targeted impairment of insulin action in muscle and adipose tissue.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980709-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Exocytosis of insulin promotes insulin gene transcription via the insulin receptor/PI-3 kinase/p70 s6 kinase and CaM kinase pathways.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980709-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Transgenic mice with muscle-specific insulin resistance develop increased adiposity, impaired glucose tolerance, and dyslipidemia.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980709-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980709-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Lessons learned from molecular biology of insulin-gene mutations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980709-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early-onset type-II diabetes mellitus (MODY4) linked to IPF1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980709-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lilly Lecture: molecular mechanisms of insulin resistance. Lessons from patients with mutations in the insulin-receptor gene
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980709-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pancreatic beta-cell-specific targeted disruption of glucokinase gene. Diabetes mellitus due to defective insulin secretion to glucose
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980709-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased insulin sensitivity and hypoglycaemia in mice lacking the p85 alpha subunit of phosphoinositide 3-kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980709-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of IRS-2 causes type 2 diabetes in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980709-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980709-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980709-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0092-8674(00)80709-6
1 reference
stated in
Europe PubMed Central
PubMed ID
10199397
retrieved
28 July 2017
PubMed ID
10199397
1 reference
stated in
Europe PubMed Central
PubMed ID
10199397
retrieved
28 July 2017
ResearchGate publication ID
13099615
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