(Q33694286)

28 July 2017

title

Trapping of oxidized LDL in lysosomes of Kupffer cells is a trigger for hepatic inflammation (English)

1 reference

28 July 2017

0 references

Patrick J van Gorp

4

0 references

Christoph J Binder

object named as

Christoph J Binder

10

0 references

Ronit Shiri-Sverdlov

object named as

Ronit Shiri-Sverdlov

11

0 references

Steven Olde Damink

6

object named as

Steven W Olde Damink

1 reference

28 July 2017

Veerle Bieghs

1

1 reference

28 July 2017

Sofie M A Walenbergh

2

1 reference

28 July 2017

Tim Hendrikx

3

1 reference

28 July 2017

Fons Verheyen

5

1 reference

28 July 2017

Ad A Masclee

7

1 reference

28 July 2017

Ger H Koek

8

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28 July 2017

Marten H Hofker

9

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28 July 2017

publication date

25 April 2013

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28 July 2017

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28 July 2017

volume

33

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28 July 2017

issue

7

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28 July 2017

page(s)

1056-1061

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Internalization of modified lipids by CD36 and SR-A leads to hepatic inflammation and lysosomal cholesterol storage in Kupffer cells

28 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040540

Specific immunization strategies against oxidized low-density lipoprotein: a novel way to reduce nonalcoholic steatohepatitis in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040540

Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040540

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040540

Role of scavenger receptor A and CD36 in diet-induced nonalcoholic steatohepatitis in hyperlipidemic mice.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040540

Endolysosomal phospholipidosis and cytosolic lipid droplet storage and release in macrophages

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040540

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040540

Macrophage-specific expression of human lysosomal acid lipase corrects inflammation and pathogenic phenotypes in lal-/- mice.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040540

Advanced atherosclerotic foam cell formation has features of an acquired lysosomal storage disorder

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040540

The liver as an immunological organ

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040540

Uptake and trafficking of mildly oxidized LDL and acetylated LDL in THP-1 cells does not explain the differences in lysosomal metabolism of these two lipoproteins.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040540

Oxidized low-density lipoproteins: what is understood and what remains to be clarified

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040540

Nonalcoholic fatty liver disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040540

Lysosomal cholesterol derived from mildly oxidized low density lipoprotein is resistant to efflux

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040540

Uptake of oxidized LDL by macrophages differs from that of acetyl LDL and leads to expansion of an acidic endolysosomal compartment

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040540

Uptake of oxidized LDL by macrophages results in partial lysosomal enzyme inactivation and relocation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040540

Native and modified low density lipoproteins increase the functional expression of the macrophage class B scavenger receptor, CD36.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040540

Low density lipoprotein oxidation and its pathobiological significance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040540

In vivo and in vitro uptake and degradation of acetylated low density lipoprotein by rat liver endothelial, Kupffer, and parenchymal cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040540

The role of lysosomes in inflammation and disease.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040540

Presence of a modified low density lipoprotein in humans.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040540

Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040540

Different fate in vivo of oxidatively modified low density lipoprotein and acetylated low density lipoprotein in rats. Recognition by various scavenger receptors on Kupffer and endothelial liver cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040540

Role of Kupffer cells in the pathogenesis of liver disease

21 June 2018

1 reference

Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis

21 January 2018

1 reference

Minimally oxidized low-density lipoprotein increases expression of scavenger receptor A, CD36, and macrosialin in resident mouse peritoneal macrophages

21 January 2018

1 reference

Aggregated LDL and lipid dispersions induce lysosomal cholesteryl ester accumulation in macrophage foam cells

21 January 2018

1 reference

Lysosomal sequestration of free and esterified cholesterol from oxidized low density lipoprotein in macrophages of different species.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040540

The toxicity to macrophages of oxidized low-density lipoprotein is mediated through lysosomal damage

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23617943

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inflammation and atherosclerosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23617943

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Effects of oxidized low-density lipoproteins on the hepatic microvasculature

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23617943

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/LIV.12170

1 reference

28 July 2017

1 reference

28 July 2017

1 reference