(Q33712703)

28 July 2017

Identification of small molecules enhancing autophagic function from drug network analysis (English)

1 reference

28 July 2017

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1

Francesco Iorio

1 reference

PubMed ID

20930556

28 July 2017

Nicola Brunetti-Pierri

object named as

Nicola Brunetti-Pierri

series ordinal

4

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Diego di Bernardo

object named as

Diego di Bernardo

series ordinal

3

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author name string

Antonella Isacchi

series ordinal

2

1 reference

28 July 2017

16 November 2010

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28 July 2017

1 reference

28 July 2017

6

1 reference

28 July 2017

1204-1205

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28 July 2017

8

1 reference

Target deconvolution strategies in drug discovery

28 July 2017

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Chemogenomic profiling on a genome-wide scale using reverse-engineered gene networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Network analyses in systems pharmacology

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Network pharmacology: the next paradigm in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

A systems biology approach to prediction of oncogenes and molecular perturbation targets in B-cell lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Inferring genetic networks and identifying compound mode of action via expression profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Human disease-drug network based on genomic expression profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Functional discovery via a compendium of expression profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Mistranslation of membrane proteins and two-component system activation trigger antibiotic-mediated cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

The Connectivity Map: a new tool for biomedical research

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Finding multiple target optimal intervention in disease-related molecular network.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Drug target identification using side-effect similarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Building disease-specific drug-protein connectivity maps from molecular interaction networks and PubMed abstracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Predicting new molecular targets for known drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Chemical database techniques in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Identifying network of drug mode of action by gene expression profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Space oriented rank-based data integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Clustering by passing messages between data points

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Modularity and community structure in networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Drug data coding and analysis in epidemiologic studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

DrugBank and its relevance to pharmacogenomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

ChemBank: a small-molecule screening and cheminformatics resource database

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

NVP-AUY922: a novel heat shock protein 90 inhibitor active against xenograft tumor growth, angiogenesis, and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Cardiac glycosides inhibit TNF-alpha/NF-kappaB signaling by blocking recruitment of TNF receptor-associated death domain to the TNF receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Mammalian cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Flavopiridol: the first cyclin-dependent kinase inhibitor in human clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Identification of N,1,4,4-tetramethyl-8-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide (PHA-848125), a potent, orally available cyclin dependent kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Enhanced sensitivity to irinotecan by Cdk1 inhibition in the p53-deficient HT29 human colon cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Camptothecin releases P-TEFb from the inactive 7SK snRNP complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Potential therapeutic applications of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Raised intracellular glucose concentrations reduce aggregation and cell death caused by mutant huntingtin exon 1 by decreasing mTOR phosphorylation and inducing autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Tamoxifen and AEBS ligands induced apoptosis and autophagy in breast cancer cells through the stimulation of sterol accumulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Autophagy is activated for cell survival after endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Methods for monitoring autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

The value of proteasome inhibition in cancer. Can the old drug, disulfiram, have a bright new future as a novel proteasome inhibitor?

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

The tumor proteasome is a primary target for the natural anticancer compound Withaferin A isolated from "Indian winter cherry".

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Regulation of autophagy by the inositol trisphosphate receptor

21 January 2018

1 reference

PubMed Central

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930479

The antiinflammatory sesquiterpene lactone parthenolide inhibits NF-kappa B by targeting the I kappa B kinase complex.

28 October 2018

1 reference

PubMed Central

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930479

Gossypol induces Bax/Bak-independent activation of apoptosis and cytochrome c release via a conformational change in Bcl-2

28 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1000138107

Upregulation of p21WAF1/CIP1 in human breast cancer cell lines MCF-7 and MDA-MB-468 undergoing apoptosis induced by natural product anticancer drugs 10-hydroxycamptothecin and camptothecin through p53-dependent and independent pathways

21 January 2018

1 reference

PubMed Central

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930479

18 February 2021

Identifiers

DOI

10.1073/PNAS.1000138107

1 reference

28 July 2017

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0 references

1 reference