(Q33722837)

English

The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1.

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18234899%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1 (English)

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18234899%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Alzheimer's disease

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Isidore Rigoutsos

7

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1 January 2020

author name string

Wang-Xia Wang

1

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1 January 2020

Bernard W Rajeev

2

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1 January 2020

Arnold J Stromberg

3

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1 January 2020

Na Ren

4

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1 January 2020

Guiliang Tang

5

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1 January 2020

Qingwei Huang

6

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1 January 2020

Peter T Nelson

8

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1 January 2020

language of work or name

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publication date

1 January 2008

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1 January 2020

Journal of Neuroscience

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1 January 2020

28

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1 January 2020

1213-1223

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1 January 2020

5

1 reference

Europe PubMed Central

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1 January 2020

Clinicopathologic correlations in a large Alzheimer disease center autopsy cohort: neuritic plaques and neurofibrillary tangles "do count" when staging disease severity

1 reference

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21 June 2018

A MicroRNA feedback circuit in midbrain dopamine neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

miRNAs: from neurogeneration to neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

A simple array platform for microRNA analysis and its application in mouse tissues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Induction of specific micro RNA (miRNA) species by ROS-generating metal sulfates in primary human brain cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

MicroRNA targeting specificity in mammals: determinants beyond seed pairing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Depletion of GGA3 stabilizes BACE and enhances beta-secretase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

RNA in brain disease: no longer just "the messenger in the middle".

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

An mRNA m7G cap binding-like motif within human Ago2 represses translation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Energizing miRNA research: a review of the role of miRNAs in lipid metabolism, with a prediction that miR-103/107 regulates human metabolic pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

The proteins BACE1 and BACE2 and beta-secretase activity in normal and Alzheimer's disease brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Complex translational regulation of BACE1 involves upstream AUGs and stimulatory elements within the 5' untranslated region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

miR-181a is an intrinsic modulator of T cell sensitivity and selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Characterization of microRNA expression levels and their biological correlates in human cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

microRNA expression in the prefrontal cortex of individuals with schizophrenia and schizoaffective disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

A microRNA signature of hypoxia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Genetic and pharmacological basis for therapeutic inhibition of beta- and gamma-secretases in mouse models of Alzheimer's memory deficits.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Progress toward the discovery and development of efficacious BACE inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Disease-modifying therapies in Alzheimer's disease: how far have we come?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

A pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

miRBase: the microRNA sequence database

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

The microRNA: overview of the RNA gene that modulates gene functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

BACE1 and presenilin: two unusual aspartyl proteases involved in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Transcriptional and translational regulation of BACE1 expression--implications for Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Development of BACE1 inhibitors for Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Human beta-secretase (BACE) and BACE inhibitors: progress report

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

BACE1 gene promoter is differentially regulated: detection of a novel promoter region for its cell type-specific regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Systematic identification of microRNA functions by combining target prediction and expression profiling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Mammalian microRNAs: a small world for fine-tuning gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Control of APP processing and Abeta generation level by BACE1 enzymatic activity and transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

RAKE and LNA-ISH reveal microRNA expression and localization in archival human brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Protease inhibitors as potential disease-modifying therapeutics for Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Current perspectives in intronic micro RNAs (miRNAs).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

APOE related alterations in cerebral activation even at college age.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

The Elegance of the MicroRNAs: A Neuronal Perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Extensive modulation of a set of microRNAs in primary glioblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Coenzyme A: back in action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Combinatorial microRNA target predictions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

MicroRNA-143 regulates adipocyte differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Probing microRNAs with microarrays: tissue specificity and functional inference

1 reference

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21 June 2018

The functions of animal microRNAs

1 reference

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21 June 2018

Microarray analysis of microRNA expression in the developing mammalian brain

1 reference

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21 June 2018

A combined computational-experimental approach predicts human microRNA targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

miRNP:mRNA association in polyribosomes in a human neuronal cell line.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Prediction of mammalian microRNA targets

1 reference

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21 June 2018

The microRNA world: small is mighty

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Expression of beta-secretase mRNA in transgenic Tg2576 mouse brain with Alzheimer plaque pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Characterization of Alzheimer's beta -secretase protein BACE. A pepsin family member with unusual properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

21 June 2018

Post-transcriptional contribution of a cAMP-dependent pathway to the formation of alpha- and beta/gamma-secretases-derived products of beta APP maturation in human cells expressing wild-type and Swedish mutated beta APP.

1 reference

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21 June 2018

Pantothenic acid in health and disease.

1 reference

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21 June 2018

Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

30 October 2018

A new role for microRNA pathways: modulation of degeneration induced by pathogenic human disease proteins.

1 reference

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30 October 2018

Rational probe optimization and enhanced detection strategy for microRNAs using microarrays.

1 reference

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30 October 2018

MicroRNA responses to cellular stress.

1 reference

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30 October 2018

MicroRNA pathways modulate polyglutamine-induced neurodegeneration.

1 reference

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30 October 2018

Decreased RNA, and increased RNA oxidation, in ribosomes from early Alzheimer's disease.

1 reference

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30 October 2018

Intronic microRNAs

1 reference

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30 October 2018

Beta-secretase (BACE) and GSK-3 mRNA levels in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

30 October 2018

Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837363

30 October 2018

"Preclinical" AD revisited: neuropathology of cognitively normal older adults.

1 reference

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30 October 2018

Sequestration of RNA in Alzheimer's disease neurofibrillary tangles and senile plaques.

1 reference

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30 October 2018

MicroRNA Expression Abnormalities in Pancreatic Endocrine and Acinar Tumors Are Associated With Distinctive Pathologic Features and Clinical Behavior

1 reference

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30 October 2018

Molecular biology. miRNAs in neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/18234899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of microRNAs and assays to monitor microRNA activities in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/18234899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.5065-07.2008

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18234899%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18234899%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18234899%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

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