(Q33749391)

29 July 2017

title

mTOR inhibition alleviates mitochondrial disease in a mouse model of Leigh syndrome (English)

1 reference

29 July 2017

main subject

mitochondrial disease

1 reference

Lauren Uhde

7

0 references

Anthony S Castanza

object named as

Anthony Castanza

6

0 references

Albert Quintana

object named as

Albert Quintana

4

0 references

Matt Kaeberlein

18

object named as

Matt Kaeberlein

1 reference

29 July 2017

Simon C Johnson

1

1 reference

29 July 2017

Melana E Yanos

2

1 reference

29 July 2017

Ernst-Bernhard Kayser

3

1 reference

29 July 2017

Maya Sangesland

5

1 reference

29 July 2017

Jessica Hui

8

1 reference

29 July 2017

Valerie Z Wall

9

1 reference

29 July 2017

Arni Gagnidze

10

1 reference

29 July 2017

Kelly Oh

11

1 reference

29 July 2017

Brian M Wasko

12

1 reference

29 July 2017

Fresnida J Ramos

13

1 reference

29 July 2017

Richard D Palmiter

14

1 reference

29 July 2017

Peter S Rabinovitch

15

1 reference

29 July 2017

Philip G Morgan

16

1 reference

29 July 2017

Margaret M Sedensky

17

1 reference

29 July 2017

language of work or name

English

0 references

publication date

14 November 2013

1 reference

29 July 2017

1 reference

29 July 2017

volume

342

1 reference

29 July 2017

issue

6165

1 reference

29 July 2017

page(s)

1524-1528

1 reference

Molecular mechanisms underlying genotype-dependent responses to dietary restriction.

29 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055856

Cellular and animal models for mitochondrial complex I deficiency: a focus on the NDUFS4 subunit.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055856

mTOR is a key modulator of ageing and age-related disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055856

The spectrum of pyruvate dehydrogenase complex deficiency: clinical, biochemical and genetic features in 371 patients

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055856

Rapamycin reverses elevated mTORC1 signaling in lamin A/C-deficient mice, rescues cardiac and skeletal muscle function, and extends survival.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055856

mTOR signaling in growth control and disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055856

Complex I deficiency due to loss of Ndufs4 in the brain results in progressive encephalopathy resembling Leigh syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055856

Calorie restriction: decelerating mTOR-driven aging from cells to organisms (including humans).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055856

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055856

Mice with mitochondrial complex I deficiency develop a fatal encephalomyopathy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055856

Immunosuppressive agents in solid organ transplantation: Mechanisms of action and therapeutic efficacy.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055856

The incidence of mitochondrial encephalomyopathies in childhood: clinical features and morphological, biochemical, and DNA abnormalities

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055856

cAMP-dependent phosphorylation of the nuclear encoded 18-kDa (IP) subunit of respiratory complex I and activation of the complex in serum-starved mouse fibroblast cultures

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055856

Leigh syndrome, a mitochondrial encephalo(myo)pathy. A review of the literature

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055856

Leigh syndrome: serial MR imaging and clinical follow-up

21 June 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24231806

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.1244360

1 reference

release_nv2d3k6gtffslnal7iommlhvqq

29 July 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/nv2d3k6gtffslnal7iommlhvqq

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

4055856

1 reference

29 July 2017

1 reference