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Herpes simplex virus ICP0 mutants are hypersensitive to interferon
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Europe PubMed Central
PMCID
111685
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10644380%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
title
Herpes simplex virus ICP0 mutants are hypersensitive to interferon
(English)
1 reference
stated in
Europe PubMed Central
PMCID
111685
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10644380%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
author
James Smiley
series ordinal
3
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Europe PubMed Central
PMCID
111685
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10644380%20AND%20SRC:MED&resulttype=core&format=json
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3 November 2019
author name string
K L Mossman
series ordinal
1
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Europe PubMed Central
PMCID
111685
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10644380%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
H A Saffran
series ordinal
2
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PMCID
111685
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10644380%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
publication date
1 February 2000
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Europe PubMed Central
PMCID
111685
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10644380%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
published in
Journal of Virology
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stated in
Europe PubMed Central
PMCID
111685
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10644380%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
volume
74
1 reference
stated in
Europe PubMed Central
PMCID
111685
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10644380%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
page(s)
2052-2056
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stated in
Europe PubMed Central
PMCID
111685
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10644380%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
issue
4
1 reference
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Europe PubMed Central
PMCID
111685
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10644380%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
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Truncation of the C-terminal acidic transcriptional activation domain of herpes simplex virus VP16 renders expression of the immediate-early genes almost entirely dependent on ICP0
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ICP22 and the UL13 protein kinase are both required for herpes simplex virus-induced modification of the large subunit of RNA polymerase II.
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Viral immediate-early proteins abrogate the modification by SUMO-1 of PML and Sp100 proteins, correlating with nuclear body disruption
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Interferons regulate the phenotype of wild-type and mutant herpes simplex viruses in vivo
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A viral activator of gene expression functions via the ubiquitin-proteasome pathway
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The ability of herpes simplex virus type 1 immediate-early protein Vmw110 to bind to a ubiquitin-specific protease contributes to its roles in the activation of gene expression and stimulation of virus replication.
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ND10 protein PML is recruited to herpes simplex virus type 1 prereplicative sites and replication compartments in the presence of viral DNA polymerase
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The herpes simplex virus US11 protein effectively compensates for the gamma1(34.5) gene if present before activation of protein kinase R by precluding its phosphorylation and that of the alpha subunit of eukaryotic translation initiation factor 2.
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The disruption of ND10 during herpes simplex virus infection correlates with the Vmw110- and proteasome-dependent loss of several PML isoforms
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Molecular mechanisms of interferon resistance mediated by viral-directed inhibition of PKR, the interferon-induced protein kinase
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4 July 2018
Truncation of the C-terminal acidic transcriptional activation domain of herpes simplex virus VP16 produces a phenotype similar to that of the in1814 linker insertion mutation
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4 July 2018
Suppression of the phenotype of gamma(1)34.5- herpes simplex virus 1: failure of activated RNA-dependent protein kinase to shut off protein synthesis is associated with a deletion in the domain of the alpha47 gene
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A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein
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4 July 2018
Wherefore interferon?
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Differentiation of the shutoff of protein synthesis by virion host shutoff and mutant gamma (1)34.5 genes of herpes simplex virus 1.
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4 July 2018
The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-
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4 July 2018
A herpesvirus genetic element which affects translation in the absence of the viral GADD34 function
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Inhibition of herpes simplex virus type 1 immediate-early gene expression by alpha interferon is not VP16 specific
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Isolation of a herpes simplex virus type 1 mutant with a deletion in the virion host shutoff gene and identification of multiple forms of the vhs (UL41) polypeptide.
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Quiescent viral genomes in human fibroblasts after infection with herpes simplex virus type 1 Vmw65 mutants
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4 July 2018
An activity specified by the osteosarcoma line U2OS can substitute functionally for ICP0, a major regulatory protein of herpes simplex virus type 1
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Inhibition of Herpes Simplex Virus Type 1 Specific Translation in Cells Treated with Poly(rI).poly(rC)
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Interferon action: inhibition of vesicular stomatitis virus RNA synthesis induced by virion-bound polymerase
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4 July 2018
Deletion mutants in the gene encoding the herpes simplex virus type 1 immediate-early protein ICP0 exhibit impaired growth in cell culture
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4 July 2018
Isolation and characterization of a herpes simplex virus type 1 mutant containing a deletion within the gene encoding the immediate early polypeptide Vmw110.
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4 July 2018
Interferon inhibits herpes simplex virus-specific translation: a reinvestigation
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4 July 2018
Interferon treatment inhibits onset of herpes simplex virus immediate-early transcription
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4 July 2018
Purification of a set of cellular polypeptides that bind to the purine-rich cis-regulatory element of herpes simplex virus immediate early genes
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4 July 2018
Herpes simplex virus type 1 ICP0 plays a critical role in the de novo synthesis of infectious virus following transfection of viral DNA.
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4 July 2018
A herpes simplex virus type 1 mutant containing a deletion within immediate early gene 1 is latency-competent in mice
1 reference
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4 July 2018
Construction and characterization of a herpes simplex virus type 1 mutant unable to transinduce immediate-early gene expression
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4 July 2018
Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency
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4 July 2018
Characterization of the early steps of herpes simplex virus replication in interferon-treated human cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111685
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4 July 2018
Specific effect of interferon on the herpes simplex virus type 1 transactivation event
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111685
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4 July 2018
Hexamethylene bisacetamide stimulates herpes simplex virus immediate early gene expression in the absence of trans-induction by Vmw65
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111685
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4 July 2018
Human cytomegalovirus inhibits IFN-alpha-stimulated antiviral and immunoregulatory responses by blocking multiple levels of IFN-alpha signal transduction.
1 reference
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PubMed Central
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retrieved
30 October 2018
Herpes virus induced proteasome-dependent degradation of the nuclear bodies-associated PML and Sp100 proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111685
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30 October 2018
The comparative anti-herpes simplex virus effects of human interferons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111685
retrieved
30 October 2018
Modification of discrete nuclear domains induced by herpes simplex virus type 1 immediate early gene 1 product (ICP0).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111685
retrieved
30 October 2018
Inhibition of transcription of herpes simplex virus immediate early genes in interferon-treated human cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111685
retrieved
30 October 2018
Identifiers
DOI
10.1128/JVI.74.4.2052-2056.2000
1 reference
stated in
Europe PubMed Central
PMCID
111685
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10644380%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
PMCID
111685
1 reference
stated in
Europe PubMed Central
PMCID
111685
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10644380%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
PubMed ID
10644380
1 reference
stated in
Europe PubMed Central
PMCID
111685
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10644380%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
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